European Curriculum Vitae

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1 European Curriculum Vitae Personal information First name / Surname Address Telephone(s) Mobile phone Fax Work Personal Nationality Date of birth Gender Degree Professional Medical Qualification Fellowship PhD program AIL Emergency Medical Service Claudio Cerchione Viale Augusto 140, 80125, Naples, Italy claudio.cerchione@unina.it claudiocerc@hotmail.com Italian 19/02/1984 M Degree in Medicine, University Federico II, Napoli, Italy, 110 cum laude (Final thesis in Hematology New TKI in CML) 270/270, February 2009, School of Medicine University Federico II, Naples, Italy Hematology, 50 cum laude, July 2014, University Federico II, Naples, Italy Italy (Final Thesis in Myelodysplastic Syndromes) Advanced therapies in Medicine, University Federico II, Naples, Italy (Director prof Giovanni Di Minno) Home care doctor in Hematology (since November 2014) ASL Napoli 1 (also Secondigliano Jail, Naples) since September 2011 Experience as Specialist Membership Pediatric oncohematology Santobono-Pausilipon Hospital since July 2014 AIL (Associazione Italiana contro Leucemie-Linfomi-Mielomi) since 2009 SIE (Società Italiana di Ematologia) since 2009 EHA (European Hematology Association) since 2009

2 Personal targets To perform clinical research and clinical activities in the field of Multiple Myeloma, to improve personal clinical skills and biological knowledge, to apply the most up to date diagnostic and therapeutic procedures, to finally ameliorate quality of medical care in the place I work, through foreign working experiences in international reference centers. Work experience September 2014 Today July 2014 Today July 2009 July 2014 In charge for Clinical management of Multiple Myeloma/MGUS (Supervision Prof. F. Pane), Hematology Division, University of Naples Federico II, Italy. Work as Pediatric OncoHematology Specialist, Santobono-Pausilipon Hospital, Naples, Italy Fellowship in Hematology, Hematology Division, University of Naples Federico II, Italy: - Clinical management of Chronic Myeloid Leukemia, Anemia and Myelodysplastic syndromes, Lymphoproliferalive disorders (particularly non-hodgkin and Hodgkin Disease), Pediatric oncohematology, Multiple Myeloma and Ph- Myeloproliferative neoplasm. Sep 2006 June 2009 Internal student, Hematology Division, University of Naples Federico II, Italy. Sep 2008 Oct 2008 Sep 2005 Sep 2006 Sep 2002 June 2009 Visiting Medical Student (Clinical Clerkship) Research and clinical activities in Hematology Department, Hospitais da Universidade de Coimbra (Director prof Adriana Teixeira), Portugal Visiting Medical Student (Erasmus project) Research and clinical activities in Hematology Department, Friedrich-Wilhelms Universitat Bonn (Director prof Schmidt Wolf), Germany Medical Graduation, School of Medicine Federico II, Italy September 1997 June 2002 High school Graduation, Scientific Lyceum N. Copernico, Naples, Italy

3 Clinical investigation Feb 2015 Today Sep 2011 Today Participation [PhD program] in clinical trial for Acute Leukemias performed in Hematology Division, Federico II, Naples, Italy (Front-line central vascular access devices in acute leukemias peripherally inserted catheter (PICC) versus traditional venous catether (CVC) : a phase IV randomized trial (NCT ) Partecipation in RECAMDS (Regional Myelodysplasic Syndromes Register) Mar 2012 Today Sub-investigator of following clinical trial (GCP Training : 15/06/2011, University Federico II, Naples, Italy) : MORE Revlimid/Lenalidomide in del 5q syndrome (Celgene) Denosumab in Multiple Myeloma (AMGEN) Pegilated GCSF in LNH (TEVA) GOYA (LNH, ROCHE) TOWER-AMG103 (Blinatumomab in LLA) Fields of interest and research - Clinical management and research on Multiple Myeloma, with particular interest in imaging diagnostic techniques, alternative chemotherapy regimens and transplantation procedures. - Clinical management on Chronic Myeloid Leukemia, with research interest on mechanisms of second generation TKIs. - Clinical management of Myelodysplastic Syndromes, with particular interest on role of demethylating agents. - Clinical management of Pediatric Acute Leukemias - Clinical management of Infections in Hematologic patients, with particular interest in diagnostic tools and imaging techniques, especially for invasive fungal infections Education and training 1 April 2014 Ph.D. attendant, Hematology Division, University of Naples, Italy. 30 June 2009 Residency in Hematology, University of Naples, Italy, with full marks. 22 July 2002 M.D., University of Naples, Italy, with full marks.

4 Personal skills and competences Native Speaking Italian Other language English (Certificate C1.2 British Council, Naples, Italy) Understanding Speaking Writing Excellent Excellent Excellent German (Certificate B2, Rheinische Friedrich-Wilhelms Universitat, Bonn, Germany) Understanding Speaking Writing Very Good Very Good Very Good Personal skills and competences Computer skills and competences Excellent knowledge of Office packages (Word, Excel, Power-point), Internet Explorer, Mozilla Firefox and client (Outlook express), Operating systems (Microsoft Windows and Mac OS) User of statistical program (STAT v7, SPSS). Driving licence European Driving license, type B BLSD (Basic Life Support early Defibrillation) (17/07/2010) AOU Federico II - Napoli P.T.C. (Pre-Hospital Trauma Care) (18/09/2010) AOU Federico II Napoli Awards 1) Travel Grant winner at the 8th Stem Cell Course- Collegio Ghislieri, Pavia 2) Travel Grant winner at the 9th Stem Cell Course- Collegio Ghislieri, Pavia 3) Travel Grant winner at the 10th Stem Cell Course- Collegio Ghislieri, Pavia 4) Travel Grant winner at the 11th Stem Cell Course- Collegio Ghislieri, Pavia 5) Travel Grant winner at the 12th Stem Cell Course- Collegio Ghislieri, Pavia 6) Travel Grant winner at the 13th Stem Cell Course- Collegio Ghislieri, Pavia 7) iacademy Award 2013 Napoli 8) iacademy Award 2014 Napoli 9) Winner of Progressi in Ematologia I giovani come protagonisti - SIE Giovani (Stazione Marittima, Napoli)

5 Editorial Board Member 1) Jacobs Journal of Hematology Reviewer in : 1) PlosOne 2) Annals of Clinical Cytology and Pathology 3) World Journal of Methodology 4) World Journal of Orthopedics 5) World Journal of Gastroenterology Pharmacology and Therapeutics 6) Hematology 7) World Journal of Hematology Oral presentations : 1) Successful pregnancies in Chronic Myeloid Leukaemia male patient on Imatinib therapy Annual meeting of Centri di Ematologia Meridionale ed Insulare (SIE SUD), October 2010, Castellaneta Marina (Taranto, Italy) 2) Renal failure associated to tyrosine kinase inhibitors Annual meeting of Centri di Ematologia Meridionale ed Insulare (SIE SUD), October 2010, Castellaneta Marina (Taranto, Italy) 3) Monitoraggio dei livelli plasmatici degli antimicotici azolici nei pazienti neutropenici e correlazioni con efficacia terapeutica ed effetti tossici Under40 Project in Hematology, November 2012, Napoli, Italy 4) Terapia combinata con voriconazolo e caspofungina : una nuova arma contro l Aspergillosi invasive iacademy Award November 2013, Napoli, Italy 5) Ruolo della Bendamustina nel paziente con Mieloma Multiplo Recidivato e Refrattario Policlinico AOU Federico II 3 April 2014, Napoli, Italy 6) Analisi della risposta agli agenti eritrostimolanti in una coorte di pazienti affetti da syndrome mielodisplastica low-risk afferenti al Registro Campano per le MDS Italian Red Cell Club October 2014, San Marcellino e Festo Napoli, Italy 7) Efficacia del Voriconazolo nell aspergillosi refrattaria alla terapia con amfotericina B : la nostra esperienza iacademy Award November 2014, Avellino, Italy 8) Mieloma Multiplo : Strategie a confronto : Switch : bilancio tra sostenibilità ed efficacia 23 April 2015, Hotel Royal Napoli 9) Il mielodisplastico alto rischio : ruolo degli agenti ipometilanti La gestione delle alterazioni della crasi ematica e delle tossicità da chemioterapia : confronto tra esperti II Edizione 4 Giugno 2015, Hotel Montespina, Napoli 10) Il mielodisplastico non trasfusione dipendente : ruolo dell Epoietina La gestione delle alterazioni della crasi ematica e delle tossicità da chemioterapia : confronto tra esperti II Edizione 4 Giugno 2015, Hotel Montespina, Napoli

6 PUBBLICATIONS Papers: 1) Cerchione C, Fabbricini R, Pane F, Luciano L. Vitiligo-like lesions in an adult patient treated with Imatinib Mesylate Leukemia Research : 2009 Aug; 33 (8): e Epub 2009 Feb 20. 2) Pane F, Quintarelli F, Esposito N, Izzo B, De Angelis B, Peluso A, Muccioli Casadei G, Cosenza M, Cerchione C, Camera A, Luciano L Acute and Chronic Ph+ Leukemias: differential leukemogenesis pathways translate into different clinical needs (Hematologica, Vol.94 Supplement n 4, October 2009) 3) Cerchione C, Catalano L, Cerciello G, Avilia S, Picardi M, Risitano AM, Pisano I, Alfinito F, Pane F Role of Lenalidomide in the management of myelodysplastic syndromes with del(5q) associated with pure red cell aplasia (PRCA) Ann Hematol Aug 20. 4) C. Cerchione, A. De Renzo, N. Pugliese, E. Seneca, R. Della Pepa, C. Cimmino, C. Mainolfi, M. Picardi, F. Pane Ruolo della bendamustina nel paziente con linfoma non-hodgkin di tipo follicolare in progressione in corso di chemioterapia convenzionale secondo schema R-CHOP Questioni di Clinica, Anno X n.2 (Suppl. 3)/2014 5) Cerchione C, Catalano L, Pareto AE, Picardi M, Pane F Pegfilgrastim in primary prophylaxis of febrile neutropenia during chemotherapy of relapsed and refractory multiple myeloma : a real-life experience Support Care Cancer 2015 Feb;23(2) : ) Fonti R, Pace L, Cerchione C, Catalano L, Salvatore B, De Luca S, Pane F, Salvatore M, Del Vecchio S 18-FDG PET/CT, 99mTc-MIBI, and MRI in the Prediction of Outcome of Patients With Multiple Myeloma : A Comparative Study Clin Nucl Med 2015 Apr;40(4): ) Cerchione C, Catalano L, Pareto A.E., Lucignano M, Pane F Ruolo del retreatment con bendamustina nel paziente con mieloma multiplo recidivato e refrattario Questioni di Clinica Esperienze Cliniche in ematologia sul territorio nazionale Volume 11 8) Cerchione C, Lucignano M, Pane F, Catalano L Salvage therapy with pegylated liposomial doxorubicin-based regimen in relapsed/refractory multiple myeloma : comments to the article by Romano et al. Eur J Haematol Nov 21 Abstracts : 1) Luciano L, Cerchione C, Becchimanzi C, Pane F, Rotoli B. Imatinib Mesylate and Cardiac function Haematologica Abstract Book, SIE, Vol. 92 supplement no.3, October ) V. Schiano Lomoriello, R.Esposito, R.Viceconti, C.Cerchione, L.Luciano, M.Galderisi L'Imatinib aumenta la massa ventricolare ed il diametro atriale sinistro nei pazienti affetti da leucemia mieloide cronica Giornale Italiano di Cardiologia volume 9, Suppl.2 al n.5 Maggio ) Olim P, Sousa P, Carda J, Sousa M.I., Tavares P, Cerchione C Linfoma osseo primario a experiencia de uma instituicao Abstract Congresso Nazionale Società Portoghese di Ematologia Settembre ) Luciano L, Cerchione C, Schiano Lomoriello V, Esposito R, Fabbricini R, Galderisi M, Pane F, Rotoli B Effect of Imatinib Mesylate on cardiac function Haematologica Abstract Book, SIES, Vol. 93 supplement no.2, September 2008

7 5) Caliendo I, Luciano L, Danise P, Rivellini F, De Vita B, Guerriero A, Cerchione C, Tafuri A, Clemente L, Ingenito M, D'Arco A Progression of a myelodysplastic syndrome, with nonrandom aneuploidy of chromosome 21, to acute myeloid leukemia with t(9;15) (q22;q22) as the sole cytogenetic abnormality Haematologica Abstract Book, SIES, Vol. 93 supplement no.2, September ) Luciano L, Cerchione C, Ciancia R, Pane F Renal failure associated to tyrosine kinase inhibitors Haematologica Abstract Book, EHA, Vol. 95 supplement no.2, June ) Luciano L, Cerchione C, Ciancia R, Pane F Successful pregnancies in Chronic Myeloid Leukaemia male patient on Imatinib therapy Haematologica Abstract Book, EHA, Vol. 95 supplement no.2, June ) Cerchione C, Luciano L, Ciancia R, Pane F Renal failure associated to tyrosine kinase inhibitors Abstract Book Riunione Annuale dei Centri di Ematologia Meridionale ed Insulare (SIE SUD), con Comunicazione Orale 9) Cerchione C, Luciano L, Ciancia R, Pane F Successful pregnancies in Chronic Myeloid Leukaemia male patient on Imatinib therapy Abstract Book Riunione Annuale dei Centri di Ematologia Meridionale ed Insulare (SIE SUD), con Comunicazione Orale 10) Cerchione C, Luciano L, Ciancia R, Pane F LA PATERNITA NEI PAZIENTI CON LEUCEMIA MIELOIDE CRONICA IN TERAPIA CON GLI INIBITORI DELLE TIROSINCHINASI Abstract Book Giornate Scientifiche Bruno Rotoli Federico II 11) Cerchione C, Luciano L, Ciancia R, Pane F NEFROTOSSICITA' NEI PAZIENTI CON LEUCEMIA MIELOIDE CRONICA IN TERAPIA CON GLI INIBITORI DELLE TIROSINCHINASI Abstract Book Giornate Scientifiche Bruno Rotoli Federico II 12) Della Pepa R., Cacciapuoti V., Cerciello G., Avilia S., Cerchione C., Luciano L., Alfinito F., Pane F. La tecnica FISH (Fluorescent In Situ Hybridization) è un ottimo strumento per migliorare la diagnosi delle Sindromi Mielodisplastiche Primarie (MDS) Abstract Book Giornate Scientifiche Bruno Rotoli Federico II 13) Cerchione C, Cerciello G, Della Pepa R, Ciancia R, Matarazzo M, Alfinito F, Pane F Combination of deferasirox and deferoxamine for management of iron overload in myelodysplastic syndromes in hepatopathic patient : A case report Leukemia Research, Volume 35, Supplement 1, S1-S166 (May 2011) 14) Cerciello G, Cerchione C, Cosenza M, Luciano L, Alfinito F, Pane F, Risitano AM Myelodysplastic syndromes and pure red cell aplasia with del (5q) Leukemia Research, Volume 35, Supplement 1, S1-S166 (May 2011) 15) Cerchione C, Cerciello G, Della Pepa R, Ciancia R, Matarazzo M, Alfinito F, Pane F Safety and efficacy of combination therapy with Deferasirox and Deferoxamine for management of iron overload in multitransfused hepatopatic patient with myelodysplastic syndrome : a case report Haematologica Abstract Book, EHA London, Vol. 96 supplement no.2, June ) Della Pepa R, Cerchione C, Cerciello G, Izzo B, Muccioli Casadei G, Alfinito F, Pane F Myelodysplastic syndromes with del(5q) and JAK2 V617F mutation : a case of hematologic response to Lenalidomide therapy Haematologica Abstract Book, EHA London, Vol. 96 supplement no.2, June ) Pugliese N, Gravetti A, Quintarelli C, Madonna E, Izzo B, Muccioli Casadei G, Cerchione C, Martinelli V, Pane F Hydroxyurea plus Anagrelide combined therapy is more suitable than sequence schedule of the two drugs Haematologica Abstract Book, EHA London, Vol. 96 supplement no.2, June ) Ciancia R, Cerchione C, Seneca E, Beneduce G, Pisano I, Cacciapuoti V, Luciano L, Pane F Myelodysplastic/myeloproliferative neoplasm : a future therapeutic perspective

8 Haematologica Abstract Book, SIE Napoli, Vol. 96 supplement no.3, October ) Cerchione C, Cerciello G, Della Pepa R, Avilia S, Ciancia R, Matarazzo M, Alfinito F, Pane F Management of iron overload in myelodysplastic syndromes (MDS) : combination of deferasirox and deferoxamine in a hepatopatic patient Haematologica Abstract Book, SIE Napoli, Vol. 96 supplement no.3, October ) Cerciello G, Cerchione C, Della Pepa R, Avilia S, Cosenza M, Luciano L, Alfinito F, Pane F, Risitano AM Pure red cell aplasia (PRCA) and myelodysplastic syndromes (MDS) with del (5q) Haematologica Abstract Book, SIE Napoli, Vol. 96 supplement no.3, October ) Della Pepa R, Cerchione C, Cerciello G, Avilia S, Izzo B, Muccioli Casadei G, Alfinito F, Pane F Hematologic response to Lenalidomide in JAK2 V617F-positive essential thrombocytemia (TE) associated to del (5q) myelodysplastic syndrome : a case report Haematologica Abstract Book, SIE Napoli, Vol. 96 supplement no.3, October ) Luciano L, Seneca E, Cerchione C, Ciancia R, Pisano I, Cosenza M, Peluso AL, Pane F A particular mutational status in a chronic myeloid leukemia patient treated with different tyrosin-kinase inhibitors Haematologica Abstract Book, SIE Napoli, Vol. 96 supplement no.3, October ) Pugliese N, Marano L, Gherghi M, Quintarelli C, De Angelis B, Cerchione C, Errichiello S, Muccioli Casadei G, Beneduce G, Martinelli V, Pane F Anagrelide in monotherapy or combined with hydroxyurea yields a high rate of complete response in Essential Thrombocythemia Haematologica Abstract Book, EHA Amsterdam, Vol.97 supplement no.1, June ) Pugliese N, Marano L, Picardi M, Gherghi M, Ciancia G, Cerchione C, Quintarelli C, Martinelli V, Pane F Spleen is the hidden hitch of Essential Thrombocythemia Haematologica Abstract Book, EHA Amsterdam, Vol.97 supplement no.1, June ) Cerchione C, Cerciello G, Della Pepa R, Matarazzo M, Alfinito F, Pane F Deferasirox and Deferoxamine combination therapy : a case of management of iron overload in Myelodysplastic Syndrome in an hepatopathic patient Haematologica Abstract Book, EHA Amsterdam, Vol.97 supplement no.1, June ) Cerchione C, Battipaglia G, Migliaccio I, Salvatore S, Camera A, Cerciello G, Della Pepa R, Chiurazzi F, Pane F Secondary hemophagocytic lymphohistiocytosis five years after acute myeloid leukemia : a case report Haematologica Abstract Book, Sies Roma, Vol.97 supplement no.2, October ) Claudio Cerchione, Fabrizio Pane, Marco Picardi Monitoraggio dei livelli plasmatici degli antimicotici azolici nei pazienti neutropenici e correlazioni con efficacia terapeutica ed effetti tossici Presentazione al Progetto Under40 in Hematology, Napoli ) C. Cerchione, V.Russo, F.Tucci, G.Loffredo, N.Marra, R.Parasole, F.Petruzziello, N.Crescenzio, G.Menna, V.Poggi La syndrome autoimmune linfoproliferativa (ALPS) : Esperienza del nostro centro AIEOP Librone abstract XXXVIII Congresso nazionale AIEOP, Roma, Giugno ) C. Cerchione, V.Russo, F.Tucci, G.Loffredo, N.Marra, R.Parasole, F.Petruzziello, V.Poggi Un caso di PTT in età pediatrica Librone abstract XXXVIII Congresso nazionale AIEOP, Roma, Giugno ) C. Cerchione, G. Cerciello, R. Della Pepa, N. Pugliese, L. Marano, O. Vitagliano, M. Matarazzo, F. Pane, F. Alfinito Hematology, University of Naples Federico II, Naples, Italy Combination of Deferasirox and Deferoxamine in management of iron overload in Myelodysplastic syndromes (MDS) : an update in a hepatopatic patient MDS Foundation 2013, Berlin, Abstract Book Leukemia Research, supplement May ) C. Cerchione, G. Cerciello, R. Della Pepa, N. Pugliese, L. Marano, O. Vitagliano, L. Luciano, F. Alfinito, F. Pane, A.M. Risitano Hematology, University of Naples Federico II, Naples, Italy

9 Role of Lenalidomide in management of Pure Red Cell Aplasia (PRCA) and Myelodysplastic Syndromes (MDS) with del (5q) MDS Foundation 2013, Berlin, Abstract Book Leukemia Research, supplement May ) P. Danise, O. Vitagliano, C. Cerchione, I. Soriente, A.M. D Arco, F. Pane, F. Alfinito Hematology, University of Naples Federico II, Naples, Italy Erythropoietic aspects in MDS patients responders to ESAs treatment MDS Foundation 2013, Berlin, Abstract Book Leukemia Research, supplement May ) Claudio Cerchione, Emanuela Madonna, Luana Marano, Novella Pugliese, Simona Avilia, Giuseppe Cerciello, Fabrizio Pane, Lucio Catalano BENDAMUSTINE : A NEW OPTION FOR RELAPSED/REFRACTORY MULTIPLE MYELOMA 34) Claudio Cerchione, Emanuela Madonna, Rossella Fabbricini, Luana Marano, Novella Pugliese, Fabrizio Pane, Lucio Catalano A NEW OPPORTUNITY IN RELAPLSED AND REFRACTORY MULTIPLE MYELOMA : PEGYLATED LIPOSOMAL DOXORUBICIN, CYCLOPHOSPHAMIDE AND DEXAMETHASONE (CED) 35) Claudio Cerchione, Emanuela Madonna, Rossella Fabbricini, Luana Marano, Novella Pugliese, Simona Avilia, Giuseppe Cerciello, Fabrizio Pane, Lucio Catalano TWENTY-FIVE MG LENALIDOMIDE EVERY OTHER DAY IN PATIENTS AFFECTED BY MULTIPLE MYELOMA AND RENAL FAILURE 36) Claudio Cerchione, Novella Pugliese, Luana Marano, Giuseppe Cerciello, Simona Avilia, Fabrizio Pane, Lucio Catalano PEGFILGRASTIM AS PROPHYLAXIS OF FEBRILE NEUTROPENIA DURING CHEMOTHERAPY OF RELAPSED AND REFRACTORY MULTIPLE MYELOMA 37) Claudio Cerchione, Emanuela Madonna, Rossella Fabbricini, Luana Marano, Novella Pugliese, Simona Avilia, Giuseppe Cerciello, Fabrizio Pane, Lucio Catalano DOMESTIC SUBCUTANEOUS SELF-INJECTION OF BORTEZOMIB IN MULTIPLE MYELOMA 38) Paolo Danise, Claudio Cerchione, Orsola Vitagliano, Ilaria Soriente, Alfonso Maria D'Arco, Fabrizio Pane, Fiorella Alfinito ERYTHROPOIETIC ASPECTS IN MDS PATIENTS RESPONDERS TO ESAS TREATMENT 39) Fiorella Alfinito, Orsola Vitagliano, Claudio Cerchione, Giovanna Giagnuolo, Ilaria Soriente, Alfonso Maria D'Arco, Paolo Danise, Fabrizio Pane ANALYSIS OF RESPONSE TO ERYTHROPOYESIS STIMULATING AGENTS (ESAS) IN 114 MYELODYSPLASTIC SYNDROME (MDS) PATIENTS FROM REGISTRO CAMPANO DELLE MIELODISPLASIE 40) Novella Pugliese, Claudio Cerchione, Francesco Grimaldi, Marta Raimondo, Maria Di Perna, Simona Pagliuca, Fabrizio Pane, Marco Picardi BENDAMUSTINE-BASED THERAPY IS EFFECTIVE AND HAS A FAVOURABLE TOXICITY PROFILE IN THE TREATMENT OF REFRACTORY AND RELAPSED HODGKIN LYMPHOMA. 41) Novella Pugliese, Concetta Quintarelli, Biagio De Angelis, Luana Marano, Santa Errichiello, Claudio Cerchione, Marco Picardi, Vincenzo Martinelli, Fabrizio Pane THE INTERFERON SCORE TOWARDS PREDICTION OF RESPONSIVNESS TO INTERFERON ALPHA IN ESSENTIAL THROMBOCYTHEMIA 42) Novella Pugliese, Concetta Quintarelli, Biagio De Angelis, Santa Errichiello, Luana Marano, Maddalena Raia, Claudio Cerchione, Luigi Del Vecchio, Marco Picardi, Vincenzo Martinelli, Fabrizio Pane

10 ALL-TRANS RETINOIC ACID POTENTIATES THE INHIBITORY EFFECTS OF INTERFERON ALPHA (IFN) ON CHRONIC MYELOPROLIFERATIVE NEOPLASMS (MPN) PROGENITORS IN VITRO. 43) Giovanna Giagnuolo, Claudio Cerchione, Piera Angelillo, Orsola Vitagliano, Novella Pugliese, Luana Marano, Giorgia Battipaglia, Simona Avilia, Fiorella Alfinito, Giuseppe Cerciello, Fabrizio Pane BENEFITS OF THE USE OF AZACITIDINE IN PATIENTS WITH AML REFRACTORY OR RELAPSED AFTER INTENSIVE CHEMOTHERAPY 44) Claudio Cerchione, Giuseppe Cerciello, Roberta Della Pepa, Novella Pugliese, Luana Marano, Orsola Vitagliano, Luigia Luciano, Fiorella Alfinito, Fabrizio Pane, Antonio Maria Risitano ROLE OF LENALIDOMIDE IN MANAGEMENT OF MYELODYSPLASTIC SYNDROMES (MDS) WITH DEL(5Q) ASSOCIATED WITH PURE RED CELL APLASIA (PRCA) 45) Claudio Cerchione, Giuseppe Cerciello, Roberta Della Pepa, Novella Pugliese, Luana Marano, Orsola Vitagliano, Margherita Matarazzo, Fabrizio Pane, Fiorella Alfinito COMBINATION OF DEFERASIROX AND DEFEROXAMINE IN MANAGEMENT OF IRON OVERLOAD IN MYELODYSPLASTIC SYNDROMES (MDS): AN UPDATE IN A HEPATOPATIC PATIENT 46) Giusi Barra, Claudio Cerchione, Emanuela Madonna, G.Pasquale, A.Sementa, Fabrizio Pane, Lucio Catalano, Raffaele De Palma SPHINGOSINE KINASE 2 IS OVEREXPRESSED IN PATIENTS AFFECTED BY MULTIPLE MYELOMA 47) Claudio Cerchione, Giovanna Giagnuolo, Piera Angelillo, Simona Avilia, Orsola Vitagliano, Novella Pugliese, Luana Marano, Anna Pareto, Fiorella Alfinito, Fabrizio Pane, Giuseppe Cerciello BENEFITS OF THE USE OF AZACITIDINE IN PATIENTS WITH AML REFRACTORY OR RELAPSED AFTER INTENSIVE CHEMOTHERAPY XXVI Symposium IACRLRD (International Association for Comparative Research on Leukemia and Related Diseases), Torino 2013, Abstract Book 48) Novella Pugliese, Concetta Quintarelli, Biagio De Angelis, Santa Errichiello, Luana Marano, Nicola Esposito, Claudio Cerchione, Marco Picardi, Vincenzo Martinelli, Fabrizio Pane INTERFERON SIGNATURE PREDICTS RESPONSIVENESS IN ESSENTIAL THROMBOCYTHEMIA XXVI Symposium IACRLRD (International Association for Comparative Research on Leukemia and Related Diseases), Torino 2013, Abstract Book 49) Novella Pugliese, Concetta Quintarelli, Biagio De Angelis, Santa Errichiello, Luana Marano, Maddalena Raia, Claudio Cerchione, Luigi Del Vecchio, Marco Picardi, Vincenzo Martinelli, Fabrizio Pane IN VITRO SINERGISTIC INHIBITORY EFFECTS USING COMBINATION OF INTERFERON ALPHA AND ALL-TRANS RETINOIC ACID IN CHRONIC MYELOPROLIFERATIVE NEOPLASMS (MPN) XXVI Symposium IACRLRD (International Association for Comparative Research on Leukemia and Related Diseases), Torino 2013, Abstract Book 50) Claudio Cerchione, Emanuela Madonna, Luana Marano, Novella Pugliese, Elisa Seneca, Simona Avilia, Giuseppe Cerciello, Fabrizio Pane, Lucio Catalano MANAGEMENT OF MULTIPLE MYELOMA WITH BENDAMUSTINE : A FURTHER OPTION FOR RELAPSED AND REFRACTORY PATIENTS XXVI Symposium IACRLRD (International Association for Comparative Research on Leukemia and Related Diseases), Torino 2013, Abstract Book 51) Claudio Cerchione, Novella Pugliese, Luana Marano, Giuseppe Cerciello, Simona Avilia, Elisa Seneca, Fabrizio Pane, Lucio Catalano PEGFILGRASTIM IN THE MANAGEMENT OF POSTCHEMOTHERAPY FEBRILE NEUTROPENIA IN RELAPSED AND REFRACTORY MULTIPLE MYELOMA XXVI Symposium IACRLRD (International Association for Comparative Research on Leukemia and Related Diseases), Torino 2013, Abstract Book 52) Claudio Cerchione, Paolo Danise, Orsola Vitagliano, Giuseppe Cerciello, Anna Pareto, Ilaria Soriente, Alfonso Maria

11 D Arco, Fabrizio Pane, Fiorella Alfinito EVALUATION OF ERYTHROPOIETIC ASPECTS IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES RESPONDERS TO ERYTRHOPOIESIS STIMULATING AGENTS (ESAs) XXVI Symposium IACRLRD (International Association for Comparative Research on Leukemia and Related Diseases), Torino 2013, Abstract Book 53) Claudio Cerchione, Emanuela Madonna, Luana Marano, Novella Pugliese, Simona Avilia, Giuseppe Cerciello, Fabrizio Pane, Lucio Catalano MANAGEMENT OF MULTIPLE MYELOMA WITH BENDAMUSTINE : A FURTHER OPTION FOR RELAPSED AND REFRACTORY PATIENTS 54) Claudio Cerchione, Novella Pugliese, Luana Marano, Giuseppe Cerciello, Simona Avilia, Elisa Seneca, Fabrizio Pane, Lucio Catalano PEGFILGRASTIM IN THE MANAGEMENT OF POST-CHEMOTHERAPY FEBRILE NEUTROPENIA IN RELAPSED AND REFRACTORY MULTIPLE MYELOMA 55) Paolo Danise, Claudio Cerchione, Orsola Vitagliano, Giuseppe Cerciello, Ilaria Soriente, Alfonso Maria D'Arco, Fabrizio Pane, Fiorella Alfinito EVALUATION OF ERYTHROPOIETIC ASPECTS IN PATIENTS WITH MYELODISPLASTIC SYNDROMES RESPONDERS TO ERYTHROPOIESIS STIMULATING AGENTS 56) Fiorella Alfinito, Claudio Cerchione, Orsola Vitagliano, Giovanna Giagnuolo, Giuseppe Cerciello, Ilaria Soriente, Alfonso Maria D'Arco, Paolo Danise, Fabrizio Pane ERYTHROPOYESIS STIMULATING AGENTS (ESAS) IN THE MANAGEMENT OF MYELODYSPLASTIC SYNDROMES 57) Novella Pugliese, Claudio Cerchione, Francesco Grimaldi, Marta Raimondo, Maria Di Perna, Simona Pagliuca, Fabrizio Pane, Marco Picardi EFFICACY AND SAFETY OF BENDAMUSTINE-BASED REGIMEN IN THE TREATMENT OF REFRACTORY AND RELAPSED HODGKIN LYMPHOMA. 58) Novella Pugliese, Concetta Quintarelli, Biagio De Angelis, Luana Marano, Santa Errichiello, Nicola Esposito, Claudio Cerchione, Marco Picardi, Vincenzo Martinelli, Fabrizio Pane GENE EXPRESSION DRIVES INTERFERON TAILORED THERAPY IN ESSENTIAL THROMBOCYTHEMIA 59) Novella Pugliese, Concetta Quintarelli, Biagio De Angelis, Santa Errichiello, Luana Marano, Maddalena Raia, Claudio Cerchione, Luigi Del Vecchio, Marco Picardi, Vincenzo Martinelli, Fabrizio Pane SINERGISTIC INTERACTION BETWEEN ALL-TRANS RETINOIC ACID AND INTERFERON ALPHA IN VITRO MODEL OF CHRONIC MYELOPROLIFERATIVE NEOPLASMS (MPN) 60) Claudio Cerchione, Giuseppe Cerciello, Roberta Della Pepa, Novella Pugliese, Luana Marano, Orsola Vitagliano, Luigia Luciano, Fiorella Alfinito, Fabrizio Pane, Antonio Maria Risitano MANAGEMENT OF MYELODYSPLASTIC SYNDROMES (MDS) WITH DEL(5Q) ASSOCIATED WITH PURE RED CELL APLASIA (PRCA) : ROLE OF LENALIDOMIDE 61) Claudio Cerchione, Vincenzo Russo, Francesca Tucci, Giuseppe Loffredo, Giuseppe Menna, Rosanna Parasole, Fara Petruzziello, Nicoletta Marra, Francesco Menna, Nicoletta Crescenzio, Vincenzo Poggi AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME (ALPS) : EXPERIENCE OF OUR AIEOP DEPARTMENT 62) Giovanna Giagnuolo, Claudio Cerchione, Piera Angelillo, Simona Avilia, Orsola Vitagliano, Novella Pugliese, Luana Marano, Fiorella Alfinito, Fabrizio Pane, Giuseppe Cerciello

12 BENEFITS OF THE USE OF AZACITIDINE IN PATIENTS WITH AML REFRACTORY OR RELAPSED AFTER INTENSIVE CHEMOTHERAPY 63) Fonti R, Pace L, Cerchione C, Catalano L, Seneca E, Madonna E, De Luca S, Pane F, Salvatore M, Del Vecchio S. ROLE OF 18-FDG-PET/CT, 99MTC-MIBI AND MRI IN THE PREDICTION OF OUTCOME OF MULTIPLE MYELOMA 64) Barra G, Cerchione C, Madonna E, Pasquale G, Sementa A, Pane F, Catalano L, De Palma R. OVEREXPRESSION OF SPHINGOSINE KINASE 2 IN MULTIPLE MYELOMA 65) Luana Marano, Novella Pugliese, Claudio Cerchione, Giuliana Beneduce, Concetta Quintarelli, Biagio De Angelis, Vincenzo Martinelli, Fabrizio Pane MUCOCUTANEOUS TOXICITY INDUCED BY HYDROXYUREA IN CHRONIC MYELOPROLIFERATIVE NEOPLASMS 66) Novella Pugliese, Luana Marano, Concetta Quintarelli, Biagio De Angelis, Santa Errichiello, Nicola Esposito, Claudio Cerchione, Marco Picardi, Vincenzo Martinelli, Fabrizio Pane INTERFERON ALPHA IS EFFECTIVE AND HAS A FAVOURABLE TOXICITY PROFILE IN THE TREATMENT OF ESSENTIAL THROMBOCYTHEMIA 67) Novella Pugliese, Concetta Quintarelli, Biagio De Angelis, Luana Marano, Santa Errichiello, Nicola Esposito, Maddalena Raia, Claudio Cerchione, Luigi Del Vecchio, Marco Picardi, Vincenzo Martinelli, Fabrizio Pane THE INTERFERON SCORE TOWARDS INTERFERON ALPHA TAILORED THERAPY IN ESSENTIAL THROMBOCYTHEMIA ASH Abstract Book, December ) Claudio Cerchione, Mario Masarone, Marcello Persico, Giuliana Beneduce, Clementina Cimmino, Roberta Della Pepa, Serena Luponio, Ilaria Peluso, Novella Pugliese, Elisa Seneca, Marianna Notarangelo, Ciro Mainolfi, Marco Picardi, Fabrizio Pane, Amalia De Renzo ROLE OF PROPHYLAXIS WITH LAMIVUDINE IN MAINTENANCE TREATMENT WITH RITUXIMAB IN NON HODGKIN LYMPHOMA CD20+ Haematologica Abstract Book, EHA Milano, Vol.99 supplement no.1, June ) Emanuela Madonna, Luigia Simeone, Marta Raimondo, Claudio Cerchione, Amalia De Renzo, Federico Chiurazzi, Fabrizio Pane SECONDARY MALIGNANCIES IN CHRONIC LYMPHOCYTIC LEUKEMIA : OUR EXPERIENCE Haematologica Abstract Book, EHA Milano, Vol.99 supplement no.1, June ) Claudio Cerchione, Emanuela Madonna, Anna Emanuele Pareto, Luana Marano, Novella Pugliese, Ilaria Peluso, Elisa Seneca, Giuseppe Cerciello, Simona Avilia, Santina Basile, Fabrizio Pane, Lucio Catalano MANAGEMENT OF RELAPSED AND REFRACTORY MULTIPLE MYELOMA WITH BENDAMUSTINE Haematologica Abstract Book, EHA Milano, Vol.99 supplement no.1, June ) Amalia De Renzo, Roberta Della Pepa, Serena Luponio, Claudio Cerchione, Giuliana Beneduce, Ilaria Migliaccio, Novella Pugliese, Clementina Cimmino, Elisa Seneca, Anna Emanuele Pareto, Orsola Vitgliano, Luigia Simeone, Fabrizio Pane, Giuseppe Spadaro RITUXIMAB-INDUCED HYPOGAMMAGLOBUINEMIA AND SUPPORTIVE INTRAVENOUS IG (IVIG) TREATMENT IN PATIENTS WITH NON HODGKIN LYMPHOMA Haematologica Abstract Book, EHA Milano, Vol.99 supplement no.1, June ) Amalia De Renzo, Claudio Cerchione, Fabiana Perna, Mario Masarone, Marcello Persico, Roberta Della Pepa, Clemetina Cimmino, Serena Luponio, Ilaria Peluso, Novella Pugliese, Elisa Seneca, Ciro Mainolfi, Ilario De Sio, Giuseppe Ciancia, Marco Picardi, Fabrizio Pane MANAGEMENT OF PRIMARY HEPATIC NON-HODGKIN S LYMPHOMA AND CORRELATION WITH HCV INFECTION : EXCELLENT RESULTS WITH CONVENTIONAL CHEMOTHERAPY Haematologica Abstract Book, EHA Milano, Vol.99 supplement no.1, June ) Novella Pugliese, Elisa Seneca, Lucio Catalano, Marco Picardi, Clementina Cimmino, Claudio Cerchione, Maria Di Perna, Fabrizio Pane, Amalia De Renzo

13 RISK OF SECOND MULTIPLE MYELOMA AFTER NON-HODGKIN AND HODGKIN LYMPHOMA Haematologica Abstract Book, EHA Milano, Vol.99 supplement no.1, June ) Claudio Cerchione, Clementina Cimmino, Novella Pugliese, Elisa Seneca, Roberta Della Pepa, Serena Luponio, Ciro Mainolfi, Fabrizio Pane, Amalia De Renzo MANAGEMENT OF RELAPSED/REFRACTORY LYMPHOMA WITH BRENTUXIMAB VEDOTIN : OUR EXPERIENCE IN THE TREATMENT OF YOUNG PATIENTS Haematologica Abstract Book, EHA Milano, Vol.99 supplement no.1, June ) Claudio Cerchione, Santina Basile, Vincenzo Russo, Elisa Seneca, Fabrizio Pane, Lucio Catalano PEGFILGRASTIM VERSUS FILGRASTIM IN THE MANAGEMENT OF POST-CHEMOTHERAPY NEUTROPENIA IN RELAPSED AND REFRACTORY MULTIPLE MYELOMA Haematologica Abstract Book, EHA Milano, Vol.99 supplement no.1, June ) Claudio Cerchione, Serena Luponio, Roberta Della Pepa, Ilaria Migliaccio, Giuliana Beneduce, Novella Pugliese, Elisa Seneca, Ernesto Cimino, Antonio Coppola, Anna Maria Cerbone, Antonella Tufano, Marianna Notarangelo, Ilaria Peluso, Giovanni Di Minno, Fabrizio Pane, Amalia De Renzo ACQUIRED HEMOPHILIA IN ELDERLY PATIENTS WITH NON HODGKIN S LYMPHOMA Haematologica Abstract Book, EHA Milano, Vol.99 supplement no.1, June ) Claudio Cerchione, Mario Masarone, Marcello Persico, Giuseppe Signoriello, Fabiana Perna, Clementina Cimmino, Novella Pugliese, Elisa Seneca, Ilaria Peluso, Marianna Notarangelo, Fabrizio Pane, Amalia De Renzo PROPHYLAXIS WITH LAMIVUDINE FOR THE PREVENTION OF REACTIVATION IN OCCULT HEPATITIS B (OBI) IN NHL : A COST-EFFECTIVE ANALYSIS Haematologica Abstract Book, EHA Milano, Vol.99 supplement no.1, June ) Claudio Cerchione, Orsola Vitagliano, Anna Emanuele Pareto, Ilaria Soriente, Paolo Danise, Fiorella Alfinito, Fabrizio Pane Analisi della risposta agli agenti eritrostimolanti in una coorte di pazienti affetti da syndrome mielodisplastica lowrisk afferenti al Registro Campano per le MDS Libro dei lavori - Italian Red Cell Club 2014 San Marcellino e Festo - Napoli 79) Cerchione C, Basile S, Russo V, Seneca E, Pane F, Catalano L MANAGEMENT OF POST-CHEMOTHERAPY NEUTROPENIA IN RELAPSED AND REFRACTORY MULTIPLE MYELOMA : ROLE OF PEGFILGRASTIM Haematologica Abstract Book, SIES Rimini, Vol.99 supplement no.2, October ) Alfinito F, Cerchione C, Vitagliano O, Pareto AE, Barca R, Cerciello G, Soriente I, D Arco AM, Pane F, Danise P MANAGEMENT OF MYELODYSPLASTIC SYNDROMES WITH ERYTHROPOIESIS STIMULATING AGENTS : EVALUATION OF ERYTHROPOIETIC ASPECTS AND ANALYSIS OF RESPONSE Haematologica Abstract Book, SIES Rimini, Vol.99 supplement no.2, October ) Pugliese N, Seneca E, Catalano L, Picardi M, Cimmino C, Luponio S, Cerchione C, Di Perna M, Pane F, De Renzo A INCIDENCE OF MULTIPLE MYELOMA FOLLOWING THERAPY FOR NON-HODGKIN AND HODGKIN LYMPHOMA Haematologica Abstract Book, SIES Rimini, Vol.99 supplement no.2, October ) Cerchione C, Masarone M, Persico M, Beneduce G, Cimmino C, Luponio S, Pugliese N, Seneca E, Notarangelo M, Mainolfi C, Picardi M, Pane F PROPHYLAXIS WITH LAMIVUDINE IN MAINTENANCE TREATMENT WITH RITUXIMAB IN NON HODGKIN LYMPHOMA CD20+ Haematologica Abstract Book, SIES Rimini, Vol.99 supplement no.2, October ) Cerchione C, De Renzo A, Perna F, Masarone M, Persico M, Della Pepa R, Cimmino C, Luponio S, Pugliese N, Seneca E, Peluso I, Ciancia G, Mainolfi C, De Sio I, Picardi M, Pane F PRIMARY HEPATIC NON-HODGKIN S LYMPHOMA AND CORRELATION WITH HCV INFECTION : EXCELLENT RESULTS WITH CONVENTIONAL CHEMOTHERAPY Haematologica Abstract Book, SIES Rimini, Vol.99 supplement no.2, October ) Cerchione C, Madonna E, Pareto AE, Basile S, Peluso I, Vitagliano O, Cimmino C, Simeone L, Seneca E, Pugliese N, Marano L, Pane F, Catalano L ROLE OF BENDAMUSTINE IN RELAPSED AND REFRACTORY MULTIPLE MYELOMA Haematologica Abstract Book, SIES Rimini, Vol.99 supplement no.2, October 2014

14 85) Cerchione C, Cimmino C, Luponio S, Della Pepa R, Migliaccio I, Beneduce G, Pugliese N, Seneca E, Cimmino E, Coppola A, Cerbone AM, Tufano A, Notarangelo M, Peluso I, Di Minno G, Pane F, De Renzo A MANAGEMENT OF ACQUIRED HEMOPHILIA IN ELDERLY PATIENTS WITH NON HODGKIN S LYMPHOMA Haematologica Abstract Book, SIES Rimini, Vol.99 supplement no.2, October ) Cerchione C, Masarone M, Persico M, Perna F, Cimmino C, Peluso I, Notarangelo M, Pane F, De Renzo A COST-EFFECTIVE ANALYSIS OF PROPHYLAXIS WITH LAMIVUDINE FOR THE PREVENTION OF REACTIVATION IN OCCULT HEPATITIS B (OBI) IN PATIENTS WITH NON HODGKIN LYMPHOMA CD20+ UNDERGOING CHEMOTHERAPY WITH AND WITHOUT RITUXIMAB Haematologica Abstract Book, SIES Rimini, Vol.99 supplement no.2, October ) Cerchione C, Cimmino C, Pugliese N, Seneca E, Mainolfi C, Pane F, De Renzo A BRENTUXIMAB VEDOTIN IN RELAPSED/REFRACTORY LYMPHOMA : OUR EXPERIENCE IN THE TREATMENT OF YOUNG PATIENTS Haematologica Abstract Book, SIES Rimini, Vol.99 supplement no.2, October ) De Renzo A, Della Pepa R, Luponio S, Cerchione C, Beneduce G, Migliaccio I, Pugliese N, Cimmino C, Seneca E, Pareto AE, Vitagliano O, Simeone L, Pane F, Spadaro G SUPPORTIVE INTRAVENOUS IG (IVIG) TREATMENT IN RITUXIMAB-INDUCED HYPOGAMMAGLOBULINEMIA IN PATIENTS WITH NON HODGKIN LYMPHOMA Haematologica Abstract Book, SIES Rimini, Vol.99 supplement no.2, October ) Cerchione C, Vitagliano O, Simeone L, Pareto AE, Soriente I, D Arco AM, Danise P, Alfinito F, Pane F MANAGEMENT OF MYELODYSPLASTIC SYNDROMES WITH ERYTHROPOIESIS STIMULATING AGENTS : EVALUATION OF ERYTHROPOIETIC ASPECTS AND ANALYSIS OF RESPONSE Leuk Res Vol. 39 Suppl 1, S1-S166 (13th International Symposium on Myelodysplastic Syndromes (MDS)) 90) Cerchione C, De Renzo A, Masarone M, Cimmino C, Raimondo M, Signoriello G, Notarangelo M, Giagnuolo G, Persico M, Pane F COST-EFFECTIVE ANALYSIS OF PROPHYLAXIS WITH LAMIVUDINE FOR PREVENTION OF REACRIVATION IN OCCULT HEPATITIS B (OBI) IN PATIENTS WITH NON HODGKIN LYMPHOMA CD20+ UNDERGOING CHEMOTHERAPY Haematologica Abstract Book, EHA Vienna, June ) Cerchione C, Vitagliano O, Simeone L, Pareto AE, Soriente I, D Arco AM, Danise P, Alfinito F, Pane F MANAGEMENT OF MYELODYSPLASTIC SYNDROMES WITH ERYTHROPOIESIS STIMULATING AGENTS : EVALUATION OF ERYTHROPOIETIC ASPECTS AND ANALYSIS OF RESPONSE Haematologica Abstract Book, EHA Vienna, June ) Cerchione C, De Renzo A, Masarone M, Cimmino C, Persico M, Notarangelo M, Perna F, Mainolfi C, De Sio I, Ciancia G, Picardi M, Pane F MANAGEMENT OF PRIMARY HEPATIC NON HODGKIN S LYMPHOMA AND CORRELATION WITH HCV INFECTION : EXCELLENT RESULTS WITH CONVENTIONAL CHEMOTHERAPY Haematologica Abstract Book, EHA Vienna, June ) Cerchione C, Catalano L, Pareto AE, Basile S, Marano L, Peluso I, Simeone L, Vitagliano O, Palmieri S, Rocco S, Ferrara F, Pane F BENDAMUSTINE IN THE MANAGEMENT OF RELAPSED AND REFRACTORY MULTIPLE MYELOMA : A REGIONAL REAL-LIFE EXPERIENCE Haematologica Abstract Book, EHA Vienna, June ) Cerchione C, Catalano L, Pareto A.E., Basile S, Marano L, Peluso I, Simeone L, Vitagliano O, Palmieri S, Rocco S, Ferrara F, Pane F BENDAMUSTINE-BORTEZOMIB-DESAMETASONE (BVD) IN THE MANAGEMENT OF RELAPSED AND REFRACTORY MULTIPLE MYELOMA : A REGIONAL REAL-LIFE EXPERIENCE Leuk Res Vol 15, Suppl 3, September ) Cerchione C, Catalano L, Pareto A.E., Marano L, Basile S, Pane F PEGYLATED DOXORUBICINE, CYCLOPHOSPHAMIDE AND DEXAMETASONE (CED) : A NEW OPPORTUNITY IN RELAPSED AND REFRACTORY MULTIPLE MYELOMA Leuk Res Vol 15, Suppl 3, September 2015

15 96) Cerchione C, De Renzo A, Cimmino C, Raimondo M, Marano L, Madonna E, Di Perna M, Russo V, Mainolfi C, Picardi M, Pane F BRENTUXIMAB VEDOTIN IN THE MANAGEMENT OF RELAPSED/REFRACTORY LYMPHOMA IN YOUNG PATIENTS : OUR REAL-LIFE EXPERIENCE Haematologica Abstract Book, Sie Firenze, October ) Cerchione C, Catalano L, Pareto AE, Basile S, Marano L, Peluso I, Simeone L, Vitagliano O, Palmieri S, Rocco S, Ferrara F, Pane F BENDAMUSTINE-BORTEZOMIB-DESAMETASONE (BVD) IN THE MANAGEMENT OF RELAPSED AND REFRACTORY MULTIPLE MYELOMA : A REGIONAL REAL-LIFE EXPERIENCE Haematologica Abstract Book, Sie Firenze, October ) Cerchione C, Vitagliano O, Simeone L, Pareto AE, Cerciello G, Soriente I, D Arco AM, Danise P, Alfinito F, Pane F MANAGEMENT OF MYELODYSPLASTIC SYNDROMES WITH ERYTHROPOIESIS STIMULATING AGENTS (ESAs) : EVALUATION OF ERYTHROPOIETIC ASPECTS AND ANALYSIS OF RESPONSE Haematologica Abstract Book, Sie Firenze, October ) Claudio Cerchione, Catalano L, Pareto AE, Marano L, Basile S, Pane F PEGYLATED LIPOSOMAL DOXORUBICIN, CYCLOPHOSPHAMIDE AND DEXAMETHASONE (CED) : A NEW OPPORTUNITY IN RELAPLSED AND REFRACTORY MULTIPLE MYELOMA Haematologica Abstract Book, Sie Firenze, October ) Cerchione C, De Renzo A, Masarone M, Cimmino C, Raimondo M, Signoriello G, Notarangelo M, Giagnuolo G, Di Perna M, Russo V, Persico M, Pane F COST-EFFECTIVE ANALYSIS OF PROPHYLAXIS WITH LAMIVUDINE FOR PREVENTION OF REACRIVATION IN OCCULT HEPATITIS B IN PATIENTS WITH NON HODGKIN LYMPHOMA CD20+ UNDERGOING CHEMOTHERAPY Haematologica Abstract Book, Sie Firenze, October ) Cerchione C, De Renzo A, Masarone M, Cimmino C, Persico M, Notarangelo M, Perna F, Mainolfi C, De Sio I, Ciancia G, Picardi M, Pane F MANAGEMENT OF PRIMARY HEPATIC NON-HODGKIN S LYMPHOMA (PHL) Haematologica Abstract Book, Sie Firenze, October ) Cerchione C, De Renzo A, Cimmino C, Raimondo M, Di Perna M, Russo V, Picardi M, Pane F PEGFILGRASTIM IN PRIMARY PROPHYLAXIS OF FEBRILE NEUTROPENIA DURING RITUXIMAB-BENDAMUSTINE TREATMENT IN INDOLENT NON HODGKIN LYMPHOMA : A REAL-LIFE EXPERIENCE Haematologica Abstract Book, Sie Firenze, October ) Cerchione C, Catalano L, Pareto AE, Basile S, Marano L, Peluso I, Simeone L, Vitagliano O, Palmieri S, Rocco S, Ferrara F, Pane F Bendamustine-Bortezomib-Desametasone (BVD) in the management of Relapsed and Refractory Multiple Myeloma : A real-life experience Blood December 3, 2015, 126 (23) 104) Cerchione C, De Renzo A, Masarone M, Cimmino C, Di Perna M, Signoriello G, Persico M, Pane F Lamivudine for prevention of reactivation in occult hepatitis B in patients with non-hodgkin Lymphoma CD20+ undergoing chemotherapy : a cost-effective analysis Haematologica Abstract Book, EHA Copenaghen, June ) Cerchione C, Vitagliano O, Pareto AE, Di Perna M, Cerciello G, Soriente I, Alfinito F, Pane F Management of myelodysplastic syndromes with Erythropoiesis stimulating agents (ESAs) : a real-life experience Haematologica Abstract Book, EHA Copenaghen, June ) Cerchione C, De Renzo A, Masarone M, Cimmino C, Della Pepa R, Di Perna M, Mainolfi C, De Sio I, Ciancia G, Persico M, Pane F Management of primary hepatic non-hodgkin s lymphoma (PHL) Haematologica Abstract Book, EHA Copenaghen, June ) Gravetti A, Cerchione C, Casoria A, Pugliese N, Marano L, De Gregorio F, Di Perna M, Picardi M, Martinelli V, Pane F

16 Use of combined oral administration of analgesia and anxiolysis for pain associated with bone marrow aspiration and biopsy Haematologica Abstract Book, EHA Copenaghen, June ) De Nisco M, Cerchione C, Martinelli V, Pugliese N, Pedatella S, Catalano L, Manfra M, Marra N, Iula VD, Pagano F, Picardi M, Pane F An HPLC and 1H NMR study of the cytarabine degradation in clinical conditions to avoid drug waste, decrease therapy costs and improve patient compliance Haematologica Abstract Book, EHA Copenaghen, June ) Cerchione C, Catalano L, Pareto AE, Basile S, Marano L, Peluso I, Simeone L, Vitagliano O, Palmieri S, Ferrara F, Pane F Bendamustine-Bortezomib-Dexamethasone (BVD) in the management of relapsed and refractory multiple myeloma : a real-life experience Haematologica Abstract Book, EHA Copenaghen, June ) Cerchione C, De Renzo A, Cimmino C, Raimondo M, Di Perna M, Picardi M, Pane F Pegfilgrastim in primary prophylaxis of febrile neutropenia during rituximab-bendamustine treatment in indolent non Hodgkin lymphoma : a real-life experience Haematologica Abstract Book, EHA Copenaghen, June ) Cerchione C, Nappi D, Salvatore D, Migliaccio I, Pane F, Catalano L Pegfilgrastim versus filgrastim in the management of post-chemotherapy neutropenia in relapsed and refractory multiple myeloma in treatment with BVD (bendamustine-bortezomib-dexamethasone) Haematologica Abstract Book, EHA Copenaghen, June ) Cerchione C, Di Perna M, Della Pepa R, Pugliese N, Caprioli V, Frieri C, Pane F, Picardi M Front-line central vascular access devices in acute leukemias peripherally inserted central catether (PICC) versus traditional central venous catether (CVC) : a phase IV randomized trial (NCT ) Haematologica Abstract Book, EHA Copenaghen, June ) Cerchione C, Di Perna M, Pugliese N, Della Pepa R, Raimondo M, Pane F, Picardi M Bendamustine-brentuximab combination is effective and has a favourable toxicity profile in the treatment of refractory and relapsed Hodgkin lymphoma Haematologica Abstract Book, EHA Copenaghen, June 2016

17 CONFERENCES AND TRAINING COURSES 2 April March September September November 1 December December April April September October December February March March March June June September September ,19,20,21 October 2009 Oncologia:Problematiche e Attualità (Aula magna Policlinico Federico II) Terapie innovative in Ematologia (Grand Hotel's Parker's, Napoli) Seminario AIL pazienti Mieloma (Aula magna Policlinico Federico II) Seminario AIL pazienti Linfomi (Aula magna Policlinico Federico II) Mieloma Multiplo e Leucemia Linfatica Cronica : dalla biologia alla terapia (Grand Hotel's Parker's, Napoli) Congresso Nazionale L'errore in medicina: prevenzione e gestione delle conseguenze (Aula magna Policlinico Federico II) Sei anni di Imatinib : stato dell'arte e le esperienze campane (Aula Mediterraneo Ospedale Cardarelli) Update sulle Cardiopatie Infettive (Azienda Ospedaliera Cotugno) Meeting Educazionale in tema di Trombocitemia Essenziale (Grand Hotel Santa Lucia,Napoli) Reuniao sobre Linfomas Indolentes, Sociedade Portuguesa de Hematologia, speaker prof.robert Marcus (Hotel Mirage Cascais Lisbona, Portogallo) Highlights nelle leucemie Ph+ (Holiday Inn Napoli) Philadelphia positive Leukemias : Update e Subjective experiences (Hotel Gli Dei, Pozzuoli- Napoli) Aggiornamenti in Ematologia : Mieloma Multiplo Verso la guarigione? (Accademia Aeronautica Militare, Pozzuoli Napoli) Partecipazione con Borsa di studio all 8 Corso di Formazione avanzata Cellule Staminali e medicina rigenerativa 2009 :Attualità e prospettive (Collegio Ghislieri, Pavia) Meeting di aggiornamento in Ematologia Sperimentale Piernicola Boccuni (CEINGE, Napoli) La gestione dell Emoglobinuria Parossistica Notturna : ultimi sviluppi nella diagnosi e nel trattamento (Hotel Royal Continental, Napoli) II Stage Campano Diagnosi e Terapia dei Linfomi (CEINGE,Napoli) CML Discussion Board : Management della LMC nel 2009 : dalla ricerca alla pratica clinica (CEINGE, Napoli) Le Leucemie Ph+ nell era dei TKI (Holiday Inn,Napoli) 42 Congresso Nazionale SIE (Società Italiana di Ematologia) (Milano Convention Centre, Milano)

18 OCTOBER 1 NOVEMBER November November November FEBRUARY FEBRUARY MARCH ,16 e 17 March APRIL April MAY JUNE OCTOBER OCTOBER OCTOBER th Nilotinib Global Investigator Meeting (Istanbul, Turkey) Corso di Aggiornamento : La Leucemia Linfatica Cronica. Come curarla Mieloma multiplo: cosa è cambiato. Confronto con gli esperti. (Hotel Royal Continental, Napoli) III Stage Campano Diagnosi e Terapia dei Linfomi (CEINGE,Napoli) Profilassi sulle infezioni fungine invasive nel paziente ematologico a rischio (Schering-Plough, Ospedale Cardarelli, Napoli) Alghoritm Plus : Philadelphia positive Leukemias : Update and subjective experiences Aggiornamenti in Ematologia : Le sindromi mielodisplastiche : come la biologia orienta le nuove strategie terapeutiche Stage in Ematologia : InHospital Meeting (Bristol-Myers Squibb, CEINGE, Napoli) Stage in Ematologia : Biologia, Clinica e Terapia della leucemia linfatica cronica (Golden Tulip Aemilia Hotel, Policlinico S.Orsola-Malpighi, Bologna) LightClub : Corso di Educazione Continua in Medicina : Workshop sulla Leucemia Mieloide Cronica (Novartis, Spineto) Partecipazione con Borsa di studio al 9 Corso di Formazione avanzata Cellule Staminali : il vero bersaglio nella cura dei tumori (Collegio Ghislieri, Pavia) CML Educational Meeting : The Management of CML: current treatment paradigms and future perspectives (Novartis Oncology, European Treatment and Outcome Study and LeukemiaNet, Hotel Royal Continental, Napoli) Appropriatezza e linee guida nelle terapie di supporto in Oncologia (Italfarmaco, A.O.R.N. Cardarelli, Napoli) Convegno AIL, Sezione di Caserta Valentina Picazio Ruolo strategico delle donazioni di cellule staminali da midollo osseo, da sangue cordonale e da sangue periferico, nella cura delle malattie oncoematologiche (Crown Plaza Hotel, Caserta) XI Congresso Nazionale SIES (Società Italiana di Ematologia Sperimentale), Torino Le Leucemie Ph+ nell era dei TKI (second edition) (Holiday Inn, Napoli)

19 28-29 OCTOBER OCTOBER NOVEMBER NOVEMBER NOVEMBER NOVEMBER FEBRUARY MARCH MARCH APRIL May MAY June JULY JULY OCTOBER 2011 MASTERCLASS in Ematologia 2010 Cavalcando alcuni argomenti in attesa di risposta (Responsabile Scientifico Prof.Sante Tura - Hotel Dino Baveno (VB)) RELATORE alla Riunione Annuale dei Centri di Ematologia Meridionale ed Insulare (SIE SUD) con 2 COMUNICAZIONI ORALI (Resp Scientifico Prof Patrizio Mazza, Castellaneta Marina Taranto) IV Stage Campano Diagnosi e Terapia dei Linfomi (CEINGE Napoli) Le Emorragie della donna in età fertile : tra fisiologia e patologie dell emostasi (Hotel dei congressi, Castellammare di Stabia) Corso di Aggiornamento : Appropriatezza nell utilizzo dei nuovi farmaci in ematologia : evidenze cliniche e confronto (Hotel Excelsior Napoli) Corso Nazionale di Aggiornamento SIE in Ematologia Clinica (Pescara, Auditorium De Cecco, presidenti prof. Tura e prof. Mandelli) Decisional Pathway in CML plus : Philadelphia positive Leukemias : Update and Subjective experiences (Hotel degli Dei Agnano (Napoli) Leucemie Acute : dal genoma al fenotipo. Basi per una Target-Tailored Therapy (Accademia Aeronautica di Pozzuoli Napoli) Blood Cancer in the Elderly European Expert Forum (Marriot Park Convention Centre Roma) La cura globale del soggetto affetto da emoglobinopatia (Direttore : Maria Domenica Cappellini Accademia Nazionale di Medicina Sezione di Ematologia Milano) Partecipazione con Borsa di studio al 10 Corso di Formazione avanzata Ricerca traslazionale in ematologia/oncologia (Collegio Ghislieri, Pavia) MdsDoc Myelodysplastic Syndrome Documentation Best practice in the treatment with hypomethylating agents (CEINGE Napoli) Training su GCP e aspetti nella qualità di conduzione degli studi clinici (Napoli Policlinico Federico II) 2 nd Update on Psoriatic Disease (Congress Center Federico II ) Mieloma Multiplo : Highlights from the International Myeloma Workshop (Castel dell Ovo Napoli) 43 Congresso Nazionale SIE (Napoli Mostra d Oltremare)

20 DECEMBER MARCH March April April May February, 1 March October October DECEMBER January, 1 February April JUNE /22 JUNE JUNE JULY SEPTEMBER SEPTEMBER rd American Society of Hematology - ASH Annual Meeting and Exposition (San Diego California, USA) Il Linfoma di Hodgkin : Siamo alla svolta finale? (Accademia Aeronautica di Pozzuoli Napoli) Il Linfoma Mantellare : la partita è in corso (Firenze) Partecipazione con Borsa di studio al 11 Corso di Formazione avanzata Medicina genomica e terapia personalizzata in ematologia/oncologia (Collegio Ghislieri, Pavia) Digital Workshop in CML 2012 (Napoli) Workshop sulla Leucemia Mieloide Cronica (Abbazia di Spineto, Sarteano (SI) Vfend-Day, il futuro è già successo (MAXXI Museo nazionale delle arti del XXI Secolo, Roma) Denosumab EU Investigator Meeting Study (Vienna, Austria) XII Congresso Nazionale SIES (Società Italiana di Ematologia Sperimentale), Roma 54 rd American Society of Hematology - ASH Annual Meeting and Exposition (Atlanta, USA) Multiple Myeloma Debates Recent Advances in Multiple Myeloma featuring Educational Updates from ASH 2012 (Berlin, Germany) Partecipazione con Borsa di studio al 12 Corso di Formazione avanzata Le nicchie delle cellule staminali somatiche normali e tumorali (Collegio Ghislieri, Pavia) I Biosimilari nel 2013 : appropriatezza e sostenibilità economica (Aula Conferenze Seconda Università di Napoli) IV Giornate Ematologiche Irpine (Aula Magna Città Ospedaliera di Avellino) 18th EHA (European Hematology Association) (Stoccolma - Svezia) Rapid Fire in Hematology (Napoli) Open questions in Hematology (Napoli) Una terapia sempre più mirata nel linfoma di Hodgkin e nei linfomi di derivazione T-linfocitaria (Hotel Royal, Napoli)