Ministero della Salute

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1 l' l' l' l' l' l' l' l' l' l' l' l' l' l' l' l' l' Ministero della Salute ROLE OF ERYTHROCYTE MEMBRANE MICRODOMAINS IN PLASMODIUM FALCIPARUM INFECTION ADENOSINE A2A RECEPTORS AS A POSSIBLE THERAPEUTIC TARGET IN NIEMANN-PICK TYPE C DISEASE. RISK SCORE OF DEVELOPING POST OPERATIVE ATRIAL FIBRILLATION CROSS SECTIONAL STUDY TO EVALUATE THE INTERACTIONS BETWEEN GUT MICROFLORA AND IMMUNE SYSTEM AT THE CROSS-ROAD OF THE PATHOGENESIS OF INFLAMMATORY BOWEL DISEASES AND IRRITABLE BOWEL SYDROME. EXPLOITATION OF HUMAN NK CELL-DERIVED EXOSOMES AS CELL-FREE SUPPORT IN TUMOR IMMUNOTHERAPY MRI EXAMINATIONS IN PATIENTS WITH PACEMAKER OR ICD: A PERSONALIZED TOOL FOR THE RISK ASSESSMENT NEW TOOLS FOR INDIVIDUAL RISK ASSESSMENT AND TREATMENT ASSIGNMENT IN PROSTATE CANCER PATIENTS NANOTECHNOLOGY FOR THE MULTIPLEX DIAGNOSIS OF INFECTIOUS DISEASES METAGENOMIC SEARCH FOR MICROBIOLOGICAL DETERMINANTS OF HUMAN TUMORS LONG-TERM PERSISTENCE OF INTEGRASE DEFECTIVE LENTIVIRAL VECTOR (IDLV) VECTORED HIV-1-ENV FOR INDUCTION OF PROTECTIVE ANTIVIRAL ANTIBODIES TOXINS PRODUCED BY INTESTINAL BACTERIA AND PREDISPOSING GENETIC VARIATIONS: A DANGEROUS LINK FOR COLORECTAL CANCER DEVELOPMENT? EMERGING RESPIRATORY VIRUSES: MONITORING OF CORONAVIRUS INFECTIONS AT THE HUMAN-ANIMAL INTERFACE TRAIL RECEPTOR EMBEDDING IN MEMBRANE RAFTS COULD PREDICT CANCER CELL SUSCEPTIBILITY TO TRAIL-BASED MOLECULARLY TARGETED THERAPY DEVELOPMENT OF A SECOND GENERATION PCR-BASED REPLICON TYPING SYSTEM TO TRACE AND CONTROL THE ANTIMICROBIAL RESISTANCE SPREAD IN ENTEROBACTERIACEAE CELL-ON-CHIP TECHNOLOGY AS A NOVEL TOOL TO INVESTIGATE THE CROSSTALK BETWEEN CANCER AND IMMUNE CELLS: ROLE OF THE TRANSCRIPTION FACTORS INTERFERON REGULATORY FACTOR 1 AND 8 (IRF1, IRF8) IN MELANOMA AS A MODEL SYSTEM. CCL2/CCR2 BLOCKING:MOLECULAR INSIGHTS INTO A POTENTIAL THERAPEUTIC STRATEGY AGAINST HIV REPLICATION ALTERED HOST-VIRUS INTERACTION AS CAUSE OF MULTIPLE SCLEROSIS: FOCUS ON EPSTEIN-BARR VIRUS AND ANTIVIRAL IMMUNE RESPONSE ,56 GR ,76 GR ,76 GR ,28 GR ,36 GR ,76 GR ,16 GR ,16 PE ,16 PE ,36 PE ,16 PE ,16 PE ,16 RF ,16 RF ,16 RF ,16 RF ,00 RF l' l' l' l' l' l' l' l' SPECIALIZED-FUNCTIONALLY CONNECTED MEMBRANES AS CAVEOLAE AND EXOSOMES INCLUDE MOLECULAR SIGNATURE TO DECODE MELANOMA PROGRESSION MECHANISMS EXPLOITABLE IN CLINICAL THERAPY DENDRITIC CELL-BASED VACCINE THERAPY IN INDOLENT NON-HODGKIN LYMPHOMA PATIENTS: A PHASE I CLINICAL STUDY ETHYL-EICOSAPENTAENOIC ACID ADDED TO INTERFERON ß THERAPY IN RELAPSING-REMITTING MULTIPLE SCLEROSIS: A RANDOMIZED PHASE II CLINICAL TRIAL. STRUCTURE AND BIOLOGY OF THE TAT/ENV COMPLEX AND ROLE OF ANTI- TAT/ENV ANTIBODIES IN HIV INFECTION: IMPLICATION FOR HIV/AIDS PREVENTATIVE VACCINE DEVELOPMENT VIBRIO AND VIRUSES IN SHELLFISH: OLD AND EMERGING PATHOGENS. EVALUATION OF EXPOSURE LEVELS FOR THE IMPLEMENTATION OF PREVENTION STRATEGIES. THE ROLE OF THE BRAIN-ADIPOCYTE AXIS ACTIVITY IN POTENTIATING ANTIDEPRESSANT EFFICACY FROM BENCH TO BEDSIDE: AN INTEGRATED APPROACH TO RASOPATHIES ROLE OF REGULATORY CELLS AND CYTOKINES IN THE EXTENT OF COLONIC INVOLVEMENT IN PATIENTS WITH ULCERATIVE COLITIS: IMPLICATIONS FOR PATIENT-ORIENTED THERAPY ,16 RF ,16 RF ,66 RF ,16 RF ,16 RF ,16 RF ,26 RF ,86 RF l' BETA-ADRENOCEPTOR ANTAGONISM AND BIASED AGONISM IN THE CONTROL OF PATHOLOGICAL NEOVASCULARIZATION la DETERMINING RESOLVIN D1-REGULATED MECHANISMS TO HARNESS regione ABRUZZO RESOLUTION OF INFLAMMATION ,66 RF ,76 GR

2 la regione ABRUZZO la regione ABRUZZO la regione ABRUZZO la regione ABRUZZO DETERMINANTS OF THE INTERINDIVIDUAL VARIABILITY IN RESPONSIVENESS TO LOW-DOSE ASPIRIN IN PATIENTS WITH AND WITHOUT DIABETES: INSIGHTS INTO PLATELET PROTEOME AND MICRORNA PROFILE THE MIR-483-3P IN THE THERAPY OF COLORECTAL CANCER MALIGNANT HYPERTHERMIA, FROM ANESTHESIA TO HEAT- AND EXERTION- INDUCED EPISODES: UNDERSTAND THE MOLECULAR MECHANISMS TO DEVELOP INNOVATIVE THERAPEUTIC INTERVENTIONS. CENTRAL CORE DISEASE: UNDERSTAND THE MECHANISMS LEADING TO MITOCHONDRIAL DEFICIENCY/DAMAGE IN CORES TO DEVELOP EFFECTIVE PHARMACOLOGICAL TREATMENTS ,76 GR ,16 GR ,76 GR ,76 GR la regione ABRUZZO DUAL ERBB-3 AND PI3K/AKT PATHWAY INHIBITION AS A NOVEL APPROACH TO TARGETING CANCER ,16 PE la ROLE OF MICRORNAS IN MODULATING PLATELET FUNCTION IN PATIENTS regione CAMPANIA WITH ACUTE CORONARY SYNDROMES. la MICROBIOTA AS POTENTIAL TARGET FOR INNOVATIVE PREVENTIVE AND regione CAMPANIA THERAPEUTIC STRATEGIES FOR FOOD ALLERGY. la HLA-G AS PROGNOSTIC MARKER FOR CYTOMEGALOVIRUS INFECTION AND CLINICALLY RELEVANT HEART ALLOGRAFT OUTCOMES la A COMBINATION OF MIR501-5P AND MTOR AS MOLECULAR MARKERS FOR THE PROGNOSIS OF RENAL CARCINOMAS la TARGETING INFLAMMATION IN ATHEROSCLEROSIS: ROLE AND THERAPEUTIC POTENTIAL OF SPHINGOSINE 1-PHOSPHATE (S1P) AND ITS RECEPTORS la GASTRO-INTESTINAL BACTERIA, OBESITY AND INSULIN RESISTANCE la STEM CELL DYSFUNCTION AND ITS REVERSAL IN DIABETES ASSOCIATED MULTIORGAN PATHOLOGY ANALYSIS OF THE IN VITRO AND IN VIVO ROLE OF ET-1/ETAR AND CD38/CD31 la AXES IN CHRONIC LYMPHOCYTIC LEUKEMIA: PROGNOSTIC, FUNCTIONAL AND THERAPEUTIC IMPLICATIONS la la la la la la la la COPD AND EMPHYSEMA IN HIV/AIDS: AN EXAMPLE OF CHRONIC INFLAMMATION, WITH MAJOR GENETIC, ENVIRONMENTAL, CLINICAL AND PUBLIC HEALTH IMPLICATIONS LEADING TO PREMATURE AGING EXPANDING THE POTENTIALS OF NON-INVASIVE DIAGNOSIS OF CARDIAC AMYLOIDOSIS AND TAILORING APPROPRIATE MEDICAL AND SURGICAL STRATEGIES IN THE CLINICAL PRACTICE. PERINATAL DEPRESSION :CHRONOBIOLOGY,SLEEP RELATED RISK FACTOR AND LIGHT THERAPY POSITIVE SELECTION, EXPANSION AND TRANSPLANTATION OF REGULATORY T CELLS (TREGS) TO PREVENT CELLULAR REJECTION AND TO INDUCE TOLERANCE IN SOLID ORGAN TRANSPLANTATION. BREAST CANCER WITH LOW RISK OF LOCAL RECURRENCE: 3D CONFORMAL ACCELERATED AND HYPOFRACTIONATED PARTIAL BREAST IRRADIATION VS. STANDARD WHOLE BREAST RADIOTHERAPY AFTER CONSERVATIVE SURGERY INVESTIGATION OF THE ROLE OF EXTRACELLULAR ATP AND THE P2X7 RECEPTOR IN THE MODULATION OF IMMUNOSUPPRESSION WITHIN TUMOUR MICROENVIRONMENT FERTILITY PRESERVATION IN GONADOTOXIC TREATMENTS GENOMIC COMPLEXITY OF CHRONIC LYMPHOCYTIC LEUKEMIA (CLL): CLINICOBIOLOGC IMPLICATIONS AND PHARMACOECONOMIC EVALUATION AT THE BEGINNING OF THE KINASE-TARGETED TREATMENT ERA la NEUROSTEROIDS AS DETERMINANTS OF ANTIEPILEPTIC DRUG REFRACTORINESS IN TEMPORAL LOBE EPILEPSY la ROLE OF ANOCTAMIN-1 IN IODIDE TRANSPORT AND IMPLICATIONS FOR THE EFFICACY OF RADIOIODINE-BASED CANCER THERAPY. la NEW ALLOCATION CRITERIA FOR LIVER TRANSPLANTATION IN PATIENTS WITH AND WITHOUT HEPATOCELLULAR CARCINOMA BASED ON TRANSPLANT BENEFIT PRINCIPLES: A MULTICENTER, PROSPECTIVE STUDY ,76 GR ,16 PE ,76 GR ,16 GR ,76 GR ,16 GR ,96 GR ,76 GR ,68 GR ,76 GR ,16 PE ,16 RF ,13 RF ,00 RF ,00 RF ,16 RF ,16 RF ,00 RF ,16 RF

3 la la la la regione FRIULI-VENEZIA GIULIA la regione FRIULI-VENEZIA GIULIA la regione FRIULI-VENEZIA GIULIA la regione LAZIO la regione LAZIO la regione LOMBARDIA la regione LOMBARDIA la regione LOMBARDIA la regione LOMBARDIA la regione LOMBARDIA la regione MARCHE la regione MARCHE la regione MOLISE la la la la la la la ALCOHOL INTAKE AND ABUSE IN WORKPLACES: DEVELOPMENT OF AN INTEGRATED PROTOCOL BASED ON SCREENING QUESTIONNAIRE AND NEW METHODS FOR BIOLOGICAL SAMPLING AND ANALYSIS. APPLICATION IN HEALTHCARE WORKERS ACCORDING TO ITALIAN LEGISLATION IDENTIFYING LOW-VALUE HEALTH CARE INTERVENTIONS FOR PATIENTS WITH NEURODEGENERATIVE DISEASES OF THE CENTRAL NERVOUS SYSTEM AND STROKE TO SUPPORT DISINVESTMENT DECISIONS SEARCH FOR NEW GENETIC BIOMARKERS FOR EARLY DIAGNOSIS AND PREVENTION OF FAMILIAL THORACIC AORTIC ANEURYSMS AND DISSECTIONS EXERCISE TOLERANCE IN PATIENTS WITH LATE-ONSET POMPE DISEASE ON ENZYME REPLACEMENT THERAPY: EFFECTS OF EXERCISE TRAINING AND HYPERPROTEIC DIET. CARDIORIGEN - MICRORNAS INDUCING CARDIAC REGENERATION - FROM DISCOVERY TOWARDS CLINICAL APPLICATION NEW BIOMARKERS FOR EARLY SIRS/SEPSIS DIAGNOSIS IN PEDIATRIC AND ADULT PATIENS. ADHERENCE TO CHRONIC POLYTHERAPY AFTER MYOCARDIAL INFARCTION: A MULTILEVEL ANALYSIS OF PATIENT, GENERAL PRACTITIONER AND HOSPITAL OF DISCHARGE LONG TERM EXPOSURE TO AMBIENT AIR POLLUTION AND PREGNANCY OUTCOMES IN WOMEN OF THREE LARGE ITALIAN LONGITUDINAL STUDIES GENETIC BASIS OF STEROID RESISTANT NEPHROTIC SYNDROME AND IMPLICATIONS FOR THERAPY ROLE OF DRP1 AND MITOCHONDRIAL DYNAMICS IN NEURONAL AND MUSCULAR DISORDERS: MOLECULAR MECHANISMS AND THERAPEUTICS IMPLICATIONS MEASURES AND MECHANISMS OF RECOVERY OF CONSCIOUSNESS IN SEVERELY BRAIN-INJURED PATIENTS: A LONGITUDINAL, MULTIMODAL STUDY FROM THE MEASURE OF GUIDELINES ADHERENCE IN ONCOLOGY TO THE ASSESSMENT OF HEALTH SYSTEM PERFORMANCE CONTAINMENT OF A REGION-WIDE OUTBREAK OF CARBAPENEM-RESISTANT KLEBSIELLA PNEUMONIAE IN SEVEN LOMBARDIAN HOSPITAL: MOLECULAR CHARACTERIZATION, EPIDEMIOLOGY AND OUTCOME. STUDY OF THE ROLE OF EXTRACELLULAR VESICLES IN PROMOTING MYOGENIC DIFFERENTIATION SYSTEMIC SCLEROSIS AND CHRONIC GRAFT VERSUS HOST DISEASE: APPLICATION OF NOVEL PREDICTIVE ASSAYS AND GENERATION OF TRANSGENIC ANIMAL MODELS NEUROMEDIN U PATHWAY IN THE CONTROL OF OBESITY AND OTHER HYPOTHALAMUS-REGULATED PHENOTYPES NOVEL BIOMARKERS IN MALIGNANT PLEURAL MESOTHELIOMA: FROM MOLECULAR PREDICTORS OF RESPONSE-TO-THERAPY TO NOVEL MULTIMODAL THERAPEUTIC STRATEGIES IDENTIFICATION AND KILLING OF PUTATIVE CANCER STEM CELLS IN SOLID TUMORS BY IMMUNOTHERAPY WITH CYTOKINE-INDUCED KILLER CELLS METHYLATION STATUS IN SELECTED CELL GENES AND IN PAPILLOMAVIRUS GENOME AS A MARKER OF AGGRESSIVENESS IN CERVICAL LESIONS. DEFINITION OF THE ROLE OF IKB-ALPHA IN THE PATHOGENESIS AND PROGRESSION OF CHRONIC MYELOID LEUKEMIA NATIONWIDE STUDY ON TRENDS IN HOSPITAL ADMISSIONS FOR MAJOR CARDIOVASCULAR EVENTS AND PROCEDURES AMONG PEOPLE WITH AND WITHOUT DIABETES IN ITALY, IDENTIFICATION OF BIOMARKERS FOR NON MELANOMA SKIN CANCERS IN A MULTICENTER COHORT OF KIDNEY TRANSPLANT RECIPIENTS: EVALUATION OF ETHIOPATOGENETIC ROLE AND CLINICAL IMPLICATIONS. VITAMIN D DEFICIENCY AND OBESITY AFTER KIDNEY TRANSPLANTATION: MULTICENTER STUDY ON GENE-ENVIRONMENT INTERACTIONS LEADING TO "COMPLEX-PHENOTYPES" IN A HUMAN SYSTEM ASSOCIATED WITH CARDIOVASCULAR EVENTS AND GRAFT REJECTION ,16 RF ,16 RF ,16 RF ,76 GR ,16 RF ,16 RF ,76 GR ,16 RF ,16 GR ,76 GR ,76 GR ,16 RF ,16 RF ,76 GR ,16 RF ,76 GR ,76 GR ,76 GR ,76 GR ,16 GR ,16 RF ,16 RF ,16 RF

4 la la regione PUGLIA la regione PUGLIA la regione PUGLIA la regione PUGLIA la regione SARDEGNA GLP-1 AGONISTS TREATMENT VS ENDOSCOPIC PROCEDURES IN OBESITY AND TYPE II DIABETES MELLITUS MANAGEMENT: A RANDOMIZED CLINICAL TRIAL. DEVELOPMENT OF THE FIRST BIOMARKER FOR DIAGNOSIS OF IGA NEPHROPATHY EXTRACORPOREAL TREATMENTS FOR MODULATION OF INNATE IMMUNITY AND PREVENTION OF SEPSIS-INDUCED ACUTE KIDNEY INJURY INTERACTION BETWEEN ENVIRONMENTALLY SENSITIVE DNA METHYLATION AND DOPAMINE D2 RELATED GENETIC VARIATION ON SCHIZOPHRENIA PHENOTYPES MEETING SENIOR MEMBERS IN THE SEARCH FOR NEW ASSOCIATES OF THE EXCLUSIVE HAMARTROMATOUS GENE CLUB EVALUATION OF A NEW SCORE INCORPORATING ENDOTHELIAL DYSFUNCTION FOR THE ASSESSMENT OF CORONARY HEART DISEASE RISK IN PATIENTS WITH RHEUMATOID ARTHRITIS: A 3-YEAR PROSPECTIVE STUDY ,16 RF ,76 GR ,76 GR ,16 PE ,16 RF ,76 GR la MODULATION OF THE STARTLE RESPONSE IN REM SLEEP BEHAVIOR regione SARDEGNA DISORDER la DEVELOPMENT OF A NEW ENDOVASCULAR DEVICE FOR THE TREATMENT OF regione SICILIA OCCLUSIVE DISEASE OF LARGE VEINS la regione SICILIA la regione SICILIA USE OF FLAVONOIDS CONTAINED IN FLAVOCOXID TO REDUCE VASCULAR DAMAGE IN AN EXPERIMENTAL MODEL OF ATHEROSCLEROSIS HEMODYNAMIC AND BIOMARKERS FOR CLINICAL RISK STRATIFICATION OF ASCENDING THORACIC AORTIC ANEURYSM WITH BICUSPID AORTIC VALVE la ARTERIAL FUNCTION AND STRUCTURE IN INFLAMMATORY BOWEL DISEASE regione SICILIA la METABOLIC, ENDOCRINE, AND CENTRAL EFFECTS OF GENISTEIN AGLYCONE regione SICILIA IN GLUCOCORTICOID-INDUCED OSTEOPOROSIS THE GASTRIC SUBMUCOSAL SPACE (GSMS) AND THE LYMPH NODES (LN) AS la NOVEL SITES FOR ISLET ALLO-TRANSPLANTATION USING CLINICALLYregione SICILIA APPLICABLE IMMUNOSUPPRESSION la ROLE OF THE IMMUNOLOGICAL IMPAIRMENT IN PROGRESSION FROM MGUS regione SICILIA TO MULTIPLE MYELOMA la regione SICILIA la la la la la la la la la la PHASE IV CLINICAL TRIAL OF ANTI-VIRAL TREATMENT FOR HEPATITIS C INFECTION IN COMPENSATED CIRRHOSIS IH LOSS OF FUNCTION AS A MECHANISM UNDERLYING THE SELECTIVE VULNERABILITY OF NIGRAL DOPAMINE NEURONS IN PARKINSON'S DISEASE DIRECT IMMUNOFLUORESCENCE OF THE SKIN AS A TOOL FOR THE DIAGNOSIS OF CELIAC DISEASE STHARS: SURGICAL TRAINING IN IDENTIFICATION AND ISOLATION OF TUBULAR STRUCTURES WITH HYBRID AUGMENTED REALITY SIMULATION CLINICAL, GENETIC AND NEUROIMAGING PROFILES IN ITALIAN PATIENTS WITH FRONTO-TEMPORAL DEMENTIA DEVELOPMENT AND VALIDATION OF NOVEL METHODS FOR THE IN VIVO ASSESSMENT OF DISTINCT PATTERNS OF CONNECTIVITY IN THE DISORDERS OF CONSCIOUSNESS DISSECTING THE MOLECULAR BASES OF ACQUIRED RESISTANCE TO BRAF INHIBITORS IN METASTATIC MELANOMA: TOWARDS A MULTIGRUG APPROACH AUTOMATED DIGITAL SCANNING AND DIAGNOSIS OF TISSUES USING MULTIMODAL NON-LINEAR OPTICAL MICROSCOPY PERSISTENT ORGANIC POLLUTANTS AND HEAVY METALS LEVELS: THE ROLE OF DIET, LIFESTYLE AND ENVIRONMENT IN A SERIES OF 456 RESIDENTS OF TUSCANY IN RELATION TO BREAST CANCER AND NON-HODGKIN LYMPHOMA A NOVEL TEST TO DETECT HIGH RISK HUMAN PAPILLOMAVIRUS DNA IN WOMEN WITH HIGH-GRADE CERVICAL INTRAEPITHELIAL NEOPLASIA WITH SELF-COLLECTED URINE SAMPLES. ACCEPTABILITY, RELIABILITY AND DIAGNOSTIC ACCURACY OF SELF-COLLECTED URINE FOR HPV DNA TESTING WITH HC ATRIAL DILATATION AS A SUBSTRATE FOR ATRIAL FIBRILLATION IN HYPERTROPHIC CARDIOMYOPATHY: CELLULAR MECHANISMS AND NOVEL THERAPEUTIC APPROACHES ,16 PE ,16 CO ,86 GR ,00 GR ,16 GR ,16 GR ,16 PE ,16 PE ,16 RF ,76 GR ,76 GR ,20 GR ,76 GR ,76 GR ,16 GR ,16 GR ,96 GR ,16 GR ,96 GR

5 la la la la la ESTABLISHMENT OF VALID PEDIATRIC ECHOCARDIOGRAPHIC NOMOGRAMS: AN ESSENTIAL AND SURPRISINGLY LACKING TOOL FOR THE QUANTIFICATION IN THE PERFORMANCE OF A PEDIATRIC ECHOCARDIOGRAPHY. PROFILING OF HEPATOCELLULAR MIRNA CARRIED BY CIRCULATING HEPATITIS B VIRUS SURFACE ANTIGEN PARTICLES: A NON INVASIVE TOOL TO IDENTIFY CLINICALLY RELEVANT MIRNA SIGNATURES EARLY DETECTION OF DRUG RELATED FALLS, SYNCOPE OR DELIRIUM IN ELDERLY PATIENTS ADMITTED TO THE EMERGENCY DEPARTMENT OF PISA UNIVERSITY HOSPITAL: POSSIBLE IMPACT ON COST/BENEFITS AND CLINICAL OUTCOME DETECTING COPY NUMBER VARIANTS FROM WHOLE-EXOME SEQUENCING DATA APPLIED TO ACUTE MYELOID LEUKEMIAS CLONAL HETEROGENEITY AND CLONAL PROGRESSION IN THE LEUKEMIC TRANSFORMATION OF CHRONIC MYELOPROLIFERATIVE NEOPLASMS la MULTPLE SCLEROSIS REBOUND UPON FINGOLIMOD DISCONTINUATION: EVIDENCE AND MECHANISMS INVOLVED la HYPERTENSION IN HIGH SCHOOL STUDENTS:GENETIC AND ENVIRONMENTAL FACTORS la EXOME SEQUENCING OF THYMIC EPITHELIAL TUMORS HEREDITARY SCHWANNOMATOSIS: IDENTIFICATION OF NEW GENES AND la GENERATION OF ANIMAL MODELS TO DISSECT THE INTERPLAY OF THE PATHWAYS INVOLVED la la la la la la CLINICAL AND HEALTHCARE STRATEGIES FOR IMPROVING QUALITY OF LIFE IN PERSONS AFFECTED BY SPINAL CORD INJURIES: TUSCANY REGIONAL NETWORK AND USE OF INNOVATIVE TECHNOLOGICAL DEVICES DEVELOPMENT OF A SERVICE INTERFACE METHOD ( WEBSERVICE) BEETWEEN FAMILY CARE PHYSICIANS OPERATING IN A PRIMARY CARE SETTING AND NEPHROLOGISTS, FOR THE PREVENTION, DIAGNOSIS AND TREATMENT OF KIDNEY DAMAGE IN PATIENTS WITH TYPE II DIABETES MELLITUS. THERAPEUTIC CORRECTION OF MIS-SPLICED RNA TRANSCRIPTS AND OF PROTEIN CONFORMATIONAL DEFECTS IN LYSOSOMAL STORAGE DISORDERS CARPEDIEM - COMORBIDITY AND RISK PROFILES EVALUATION IN DIABETES AND HEART MORBIDITIES REPERFUSION INJURY AFTER CEREBRAL ISCHEMIA: AN "IN VIVO" STUDY USING NEURO-IMAGING MARKERS LONG TERM MECHANISMS OF DIABETES PREVENTION AND REMISSION AFTER BARIATRIC SURGERY: STUDY OF GLUCOSE METABOLISM, INSULIN SECRETION AND CARDIOVASCULAR RISK 7 YEARS AFTER ROUX-EN Y GASTRIC BYPASS. la EARLY TREATMENT OF EXERCISE-INDUCED PULMONARY HYPERTENSION IN SYSTEMIC SCLEROSIS la ELECTROMAGNETIC GUIDED IN-SITU LASER FENESTRATION OF ENDOVASCULAR ENDOPROSTHESIS la NEW SELF-POWERED DEVICES FOR COCHLEAR STIMULATION BASED ON PIEZOELECTRIC NANOMATERIALS SCREENING FOR AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE 2 IN la PATIENTS WITH AUTOIMMUNE THYROIDITIS: DEFINITION OF METHODOLOGY AND COST-BENEFIT ANALYSIS. la la la la regione UMBRIA la regione UMBRIA la la IMPLEMENTATION OF CHRONIC CARE MODEL, USING TELE-CARE AND HOME CARE, IN PATIENTS WITH MULTIPLE COMORBIDITIES: EVALUATION OF THE COST-EFFECTIVENESS AND QUALITY OF LIFE TARGETING STREPTOCOCCAL INFECTIONS IN THE MANAGEMENT OF PATIENTS WITH PSORIASIS CIRCULATING CELL-FREE BIOMARKERS IN THE DIAGNOSIS AND FOLLOW UP OF DIFFERENTIATED THYROID CANCER INDOLEAMINE 2,3-DIOXYGENASE AND PERIPHERAL TOLERANCE TO EXOGENOUS FACTOR VIII: A MULTI-CENTRE STUDY APPLICATION OF A CHEMOGENOMICS STRATEGY TO MODULATE EVI-1 IN ACUTE MYELOID LEUKEMIA TOWARDS THE PREDICTION OF DYSLIPIDEMIA FROM NEXT GENERATION SEQUENCING DATA DEVELOPMENT OF NEXT GENERATION SEQUENCING TOOLS FOR THE DIAGNOSIS OF NEURODEVELOPMENTAL DISORDERS ,00 GR ,76 GR ,76 GR ,76 GR ,76 GR ,76 GR ,16 PE ,16 PE ,72 PE ,16 RF ,16 RF ,16 RF ,16 RF ,16 RF ,76 RF ,16 RF ,16 RF ,16 RF ,16 RF ,16 RF ,16 RF ,16 RF ,16 GR ,76 GR ,76 GR ,96 GR

6 la OBESITY, HYPERTENSION AND SUBCLINICAL VASCULAR DAMAGE IN CHILDREN: THE ROLE OF DIETARY FACTORS AND LIPID MEDIATORS. AN EPIDEMIOLOGICAL AND TRANSLATIONAL STUDY ,61 GR la la HOW DOES THE CEREBELLUM CONTRIBUTE TO THE PATHOPHYSIOLOGY OF DYSTONIA? A MULTIDISCIPLINARY APPROACH WITH AD-HOC BEHAVIORAL TASKS AND CEREBELLAR STIMULATION WITH TRANSCRANIAL DIRECT CURRENT STIMULATION (TDCS) SKELETAL MUSCLE IN SPINAL AND BULBAR MUSCULAR ATROPHY (SBMA): THERAPEUTIC TARGET AND DELIVERY ROUTE FOR POTENTIAL TREATMENTS la ASSESSMENT OF STRATEGIES FOR IDENTIFYING UNDIAGNOSED TYPE 2 DIABETES MELLITUS la IMMUNOLOGICAL MECHANISMS INVOLVED IN THE PATHOGENESIS OF PRIMARY ALDOSTERONISM THE AVAILABILITY OF "OLD" AND "NEW" DRUG ELUTING STENTS IN ROUTINE CLINICAL PRACTICE: INFLUENCE ON THE TREATMENT CHOICE AMONG la MEDICAL THERAPY VS. PERCUTANEOUS CORONARY INTERVENTIONS VS. CORONARY BY-PASS SURGERY AND ON 4-YEAR CLINICAL OUTCOME IN PATIENTS W la regione LOMBARDIA la regione LOMBARDIA TOWARD THE DEVELOPMENT OF AN IN VITRO TEST FOR ALS: LARGE-SCALE VALIDATION OF PBMC PROTEIN BIOMARKERS MECHANISMS OF NEURODEGENERATION AND PHENOTYPIC HETEROGENEITY IN INHERITED PRION DISEASES: PHYSIOPATHOLOGICAL INVOLVEMENT OF PRION PROTEINS IN MEMBRANE TRAFFICKING AND SIGNALING PROOF OF CONCEPT STUDIES OF SIRT6 INHIBITORS FOR TREATING TYPE II l'irccs AOU SAN MARTINO-IST (GENOVA) DIABETES WHOLE EXOME SEQUENCING TO DISCOVER LUNG TUMOR PREDISPOSITION IN l'irccs AOU SAN MARTINO-IST (GENOVA) WOMEN WITH PREVIOUS BREAST CANCER ,16 GR ,16 RF ,16 RF ,16 RF ,16 RF ,00 RF ,00 RF ,12 GR ,76 GR l'irccs ARCISPEDALE l'irccs ARCISPEDALE l'irccs AUXOLOGICO l'irccs AUXOLOGICO l'irccs BURLO GAROFALO l'irccs BURLO GAROFALO l'irccs BURLO GAROFALO l'irccs BURLO GAROFALO l'irccs C.R.O. AVIANO l'irccs C.R.O. AVIANO l'irccs C.R.O. AVIANO l'irccs C.R.O. AVIANO l'irccs CARLO BESTA l'irccs CARLO BESTA l'irccs CARLO BESTA ANALYSIS OF GENOMIC ALTERATIONS DRIVING METASTASIS AND PROGRESSION IN PAPILLARY THYROID CARCINOMA EFFECTS OF EARLY PULMONARY REHABILITATION AND LONG-TERM EXERCISE ON FUNCTIONING, QUALITY OF LIFE AND POSTOPERATIVE OUTCOME IN LUNG CANCER PATIENTS. IDENTIFICATION OF RISK VARIANTS ASSOCIATED WITH SUSCEPTIBILITY TO SPORADIC AMYOTROPHIC LATERAL SCLEROSIS USING AN EXOME SEQUENCING APPROACH. MOLECULAR AND GENETIC INVESTIGATIONS OF THE ROLE OF BMP15 OOCYTE- DERIVED GROWTH FACTOR IN FEMALE FERTILITY GENETICOF PANIC DISORDERS TOWARDS A PERSONALIZED MEDICINE: IDENTIFICATION OF GENETIC RISK FACTORS (INCLUDING RARE VARIANTS) FOR CARDIOVASCULAR DISEASES IN ITALIAN ISOLATED POPULATIONS BY GENOME WIDE ASSOCIATION STUDIES AND NEXT GENERATION SEQUENCING DEVELOPMENTAL AND GENETIC BASES OF OPITZ G/BBB SYNDROME TOWARDS BETTER DIAGNOSIS AND MANAGEMENT OF SYNDROMIC FORMS OF INTELLECTUAL DISABILITY APPLICATIONS OF ULTRASTRUCTURAL CELL ANALYSIS IN THE FIELD OF REPRODUCTIVE TECHNOLOGIES PLEIOTROPIC TRANSCRIPTIONAL CONTROL MECHANISMS OF CD49D EXPRESSION IN TRISOMY 12 CHRONIC LYMPHOCYTIC LEUKEMIA: IMPLICATIONS FOR NOVEL THERAPEUTIC APPROACHES MYC/MIR-17~92 AXIS A NEW POTENTIAL TARGET THERAPY IN LYMPHOPROLIFERATIVE DISORDERS ROLE OF MICRORNAS IN IMMUNOGENIC TUMOR CELL DEATH A TWIST CODE OF P53 INACTIVATION IN SARCOMAS: CLINICOPATHOLOGICAL AND THERAPEUTIC IMPLICATIONS DISSECTING PHENOTYPIC AND GENETIC HETEROGENEITY IN ITALIAN ISCHEMIC STROKE PATIENTS. MECHANISMS OF SEIZURE TERMINATION IN FOCAL EPILEPSY ASSESSING THE IMMUNOMODULATORY EFFECT OF PROBIOTICS IN THE EXPERIMENTAL MODEL OF MYASTHENIA GRAVIS ,76 GR ,76 GR ,16 GR ,00 GR ,76 GR ,16 PE ,16 RF ,16 RF ,76 GR ,36 GR ,76 GR ,16 RF ,76 GR ,76 GR ,56 PE

7 l'irccs CARLO BESTA l'irccs CARLO BESTA l'irccs CARLO BESTA l'irccs CARLO BESTA l'irccs CASA SOLLIEVO SOFFERENZA l'irccs CASA SOLLIEVO SOFFERENZA l'irccs CASA SOLLIEVO SOFFERENZA l'irccs CASA SOLLIEVO SOFFERENZA l'irccs DE BELLIS l'irccs DE BELLIS l'irccs FATEBENEFRATELLI l'irccs FATEBENEFRATELLI l'irccs FATEBENEFRATELLI l'irccs FATEBENEFRATELLI l'irccs FATEBENEFRATELLI l'irccs FONDAZIONE BIETTI l'irccs GALEAZZI l'irccs GALEAZZI l'irccs GALEAZZI l'irccs GALEAZZI l'irccs GASLINI l'irccs GASLINI l'irccs GASLINI MONITORING DISEASE PROGRESSION AND PHENOTYPIC HETEROGENEITY IN HEREDITARY ATAXIAS: CLINICAL, COGNITIVE, NEUROIMAGING, AND NEUROPHYSIOLOGICAL STUDY TO IDENTIFY EARLY MARKERS OF CEREBELLAR DYSFUNCTION IN PATIENTS AND PRESYMPTOMATIC CARRIERS IDENTIFICATION OF EPILEPTOGENIC NETWORKS IN SURGICAL EPILEPSIES BY A NON-INVASIVE MULTIMODAL APPROACH TRANSLATIONAL GENETICS OF HEREDITARY SPINOCEREBELLAR DEGENERATIONS: HIGH-THROUGHPUT EXOME SEQUENCING AND MODEL ORGANISMS FOR THE IDENTIFICATION AND CHARACTERIZATION OF NOVEL DISEASE GENES IDENTIFICATION OF DETERMINANTS OF HEALTHY AGING IN ITALY (IDAGIT) DISSECTING THE TRIM8 ROLE IN THE PATHOGENESIS OF GLIOMA AND THERAPY FAMILIA: FAMILY-BASED MULTI-INTEGRATED APPROACH FOR THE IDENTIFICATION OF A NON-REDUNDANT SET OF PARATHYROID CANCER BIOMARKERS WNT5A AS A KEY REGULATOR OF INVASION IN HUMAN GBM: A STUDY ON AUTOCRINE, GLIOMA-INITIATING, STEM-LIKE CELLS TO UNRAVEL THE MOLECULAR BASIS OF NEURODEVELOPMENTAL DISORDERS TNFAR-KO T CELLS PROTECT FROM INTESTINAL INFLAMMATION IN MICE WITH MUC2 MUTATIONS, A MODEL OF HUMAN ULCERATIVE COLITS FOXO3A MEETS THE MITOCHONDRIAL GENOME: MAY THE ULTIMATE NEWCOMER SMOOTH THE WAY TOWARDS MITOCHONDRIAL MEDICINE IN COLORECTAL CANCER? THE ROLE OF THE RHO-GTPASE PROTEINS IN THE AETIOLOGY OF ALZHEIMER'S DISEASE A NON-INVASIVE, MULTIMODAL APPROACH TO RESTORE FUNCTIONAL NETWORKS AND COGNITION IN ALZHEIMER'S DISEASE AND FRONTOTEMPORAL DEMENTIA NEUROPHYSIOLOGICAL MARKERS OF NEUROPLASTICITY IN NORMAL AND PATHOLOGICAL AGING EFFICACY OF MULTIPLE NONPHARMACOLOGICAL INTERVENTIONS IN INDIVIDUALS WITH SUBJECTIVE MEMORY COMPLAINTS NEUROIMAGING AND CLINICAL MARKERS OF CHANGE IN BORDERLINE PERSONALITY DISORDER AFTER METACOGNITIVE INTERPERSONAL THERAPY MORPHOFUNCTIONAL VISUAL PATHWAYS EVALUATION IN MULTIPLE SCLEROSIS: POSSIBLE IDENTIFICATION OF NEURODEGENERATIVE BIO- MARKERS GRADE-DISPUTE. IMPROVING APPROPRIATENESS AND TRANSPARENCY OF PROCESSES TO DEVELOP GUIDELINES ON CONTROVERSIAL CLINICAL AREAS: EVIDENCE, VALUES AND CONTEXT PREFERENCES TO HELP MITIGATE DISPUTES AND ENHANCE THE APPLICABILITY OF RECOMMENDATIONS TO PRACTICE. INNOVATIVE DEVELOPMENT OF A DECELLULARIZED EQUINE-DERIVED TENDON MATRIX AS IMPLANTABLE BIOMIMETIC SUPPORT FOR TENDON AND LIGAMENT REPAIR PREDICTION OF THE RISK OF SPINAL DEFORMITIES AFTER SURGICAL DECOMPRESSION AND DEVELOPMENT OF PREVENTIVE STRATEGIES CAN MENTAL TRAINING BASED ON MOTOR IMAGERY SPEED UP THE REHABILITATION OF WALKING? EFFICACY OF A CONTROLLED PROCEDURE AND NEUROFUNCTIONAL BASES OF RECOVERY IN PATIENTS WITH TOTAL KNEE ARTHROPLASTY IDENTIFICATION OF NEW GENES FOR RARE NEURODEVELOPMENTAL DISORDERS BY HOMOZIGOSITY MAPPING/NEXT GENERATION SEQUENCING AND FUNCTIONAL STUDIES IN ZEBRAFISH INTERACTIONS OF GENOTYPE, PHENOTYPE, LOCAL IMMUNE SYSTEM AND MICROBIOLOGIC ENVIRONMENT IN THE PATHOGENESIS OF HIRSCHSPRUNG'S DISEASE ASSOCIATED ENTEROCOLITIS A MULTI-SITE INTERNATIONAL RCT COMPARING REGIONAL AND GENERAL ANESTHESIA IN INFANTS FOR EFFECTS ON NEURODEVELOPMENTAL OUTCOME AT FIVE YEAR OF AGE: THE GAS TRIAL. GENERATING STEM CELL-LIKE T CELLS TO IMPROVE IMMUNE RECONSTITUTION AND ANTI-TUMOR IMMUNITY MICROFLUIDIC INTEGRATION OF A MODEL OF THE BLOOD-BRAIN BARRIER TO INVESTIGATE IMMUNE TRAFFICKING IN MULTIPLE SCLEROSIS ,16 RF ,16 RF ,16 RF ,76 RF ,76 GR ,76 GR ,76 GR ,00 RF ,76 GR ,76 GR ,16 GR ,36 GR ,96 GR ,76 GR ,76 GR ,16 RF ,76 GR ,00 GR ,16 GR ,16 RF ,76 GR ,76 GR ,16 RF ,76 GR ,16 GR

8 COMBINING EXOME SEQUENCING AND INDUCED PLURIPOTENT STEM CELLS FOR IDENTIFICATION OF NOVEL PATHOGENETIC MECHANISMS AND THERAPIES IN HUMAN CARDIOMYOPATHIES NEW CELLULAR AND MOLECULAR MECHANISMS IN COLITIS-ASSOCIATED COLORECTAL CANCER: IMPLICATIONS FOR INNOVATIVE THERAPEUTIC APPROACHES. EXOME SEQUENCING OF OSTEOIMMUNOLOGICAL DISEASES: FROM DIAGNOSIS TO CURE OF OSTEOPETROSIS AND OTHER GENETIC SKELETAL DISEASES ,86 GR ,76 GR ,76 GR l'irccs I.N.R.C.A. l'irccs I.N.R.C.A. l'irccs I.O.V. CDK5 IN TUMOR PROGRESSION THE LONG PENTRAXIN PTX3 AS A FUNCTIONAL ANCESTOR OF ANTIBODIES IN THE IMMUNE RESPONSE TO ASPERGILLUS FUMIGATUS THE ROLE OF MACROPHAGES IN PRIMARY BILIARY CIRRHOSIS: NOVEL TARGETS FOR IMMUNE INTERVENTION ROLE OF GUT ENVIRONMENT IN THE IMMUNE RECONSTITUTION AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) DO AUTOANTIBODIES PREDICT THE ONSET OF AUTOIMMUNE DISEASES? A 13- YEAR POPULATION-BASED STUDY TO DETERMINE THE RISK OF DEVELOPING AUTOIMMUNITY IN A NORTHERN ITALIAN POPULATION PHOSHOMIMIC-PEPTIDE TECHNOLOGY TARGETING LTCCS: A NEW TOOL FOR MODULATING CONDITIONS OF PRIMARY AND POST-INFLAMMATORY CARDIOMYOPATHY INDUCED PLURIPOTENT STEM CELL (IPSC) TECHNOLOGY IN OSTEOIMMUNOLOGY: CORRECTING THE BONE AND IMMUNE DEFECTS OF OSTEOPETROSIS ESTABLISHING AND LINKING COGNITIVE AND DISEASE AND FUNCTIONAL OUTCOMES IN THE INCHIANTI STUDY THROUGH PHYSICIANS INTERVIEW AND CONSULTATION OF MEDICAL RECORD. THE "TRIPL-A STUDY". A TRIAL TO PROMOTE PHYSICAL ACTIVITY AMONG PATIENTS IN THE YOUNG-OLD AGE AFFECTED BY TYPE 2 DIABETES TARGETED SMART NANOMEDICINES FOR THE TREATMENT OF COLORECTAL CANCER METASTASIS THE 18KDA PROTEIN TSPO IS A VDAC DEPENDENT PATHWAY FOR METABOLIC RE-ADAPTATION AND MITOPHAGY EVASION IN GLIOBLASTOMA DISCLOSING ID4-DEPENDENT CROSS-TALK BETWEEN BASAL-LIKE BREAST CANCER CELLS AND TUMOR ASSOCIATED MACROPHAGES GENOMIC INSTABILITY IN HEAD&NECK CANCERS: ROLE OF GAIN OF FUNCTION ACTIVITY (GOF) OF P53 MUTANTS EXPLOITING THE PROTEIN CORONA EFFECT FOR BIOMARKER DISCOVERY AND TARGETING OF NANOMEDICINES IN PANCREATIC CANCER IDENTIFICATION OF NEW APPROACHES TARGETING ANEUPLOIDY AND CHROMOSOMAL INSTABILITY IN BREAST AND COLON CANCER METABOLIC REGULATION AND ADAPTIVE RESPONSES SUSTAINING METASTASES IN BREAST CANCER ENHANCED CELL THERAPY: NOVEL STRATEGIES TO IMPROVE TRANSPLANTED CELL SURVIVAL AND ENGRAFTMENT BY PROTECTION FROM OXIDATIVE STRESS ,76 GR ,76 GR ,76 GR ,76 GR ,76 GR ,76 GR ,00 PE ,00 PE ,76 RF ,16 GR ,52 GR ,76 GR ,76 GR ,76 GR ,76 GR ,76 GR ,16 RF l'irccs IFO - SAN GALLICANO l'irccs IRST MELDOLA (Ist. Scient. Romagnolo) l'irccs ISTITUTO DERMOPATICO DELL IMMACOLATA PRODUCTION OF NOVEL DIAGNOSTIC AND THERAPEUTIC ANTIBODIES DIRECTED AGAINST STEM CELLS IN COLORECTAL AND LUNG CANCER HUMAN PAPILLOMAVIRUS INFECTION AND CYTOLOGICAL EVALUATION OF THE ORAL AND OROPHARYNGEAL MUCOSA OF CANCER-FREE MALES AT RISK FOR SEXUALLY TRANSMITTED INFECTIONS THE ROLE OF EARLY SYSTEMATIC BEST PALLIATIVE CARE VERSUS ON REQUEST PALLIATIVE CARE CONSULTATION DURING STANDARD ONCOLOGIC TREATMENT FOR PATIENTS WITH ADVANCED GASTRIC OR PANCREATIC CANCERS: A RANDOMIZED, CONTROLLED, MULTICENTER TRIAL LEKTI, A MULTIFUNCTIONAL PROTEIN INVOLVED IN SKIN DESQUAMATION AND IMMUNITY: TOWARDS NOVEL THERAPEUTIC APPROACHES FOR RARE AND COMMON SKIN DISEASES ,16 RF ,76 GR ,16 RF ,16 RF

9 CHROP, A COMBINED CHIP-MASS SPECTROMETRY PROTEOMICS APPROACH, TO DISSECT COMPOSITION AND PLASTICITY OF THE MODIFICOME AND INTRACTOME OF CIS-REGULATORY REGIONS OF INFLAMMATORY GENES THE KINETOCHORE NDC80 COMPLEX AS A NOVEL ANTICANCER DRUG TARGET ROLE OF POLYCOMB REPRESSIVE COMPLEXES IN INTESTINE DEVELOPMENT AND COLORECTAL CANCER FORMATION. DEVELOPMENT OF CYTOCHROME C ASSAY MARKER OF ISCHEMIA/REPERFUSION DAMAGE TO THE HEART OBESITY-ASSOCIATED FLT3 MUTATIONS IN ACUTE PROMYELOCYTIC LEUKEMIA: INVESTIGATING A NOVEL PARADIGM FOR THE CANCER- PROMOTING EFFECT OF OBESITY IDENTIFICATION OF MOLECULAR TARGETS OF ANTI-TUMOR EFFECT OF CALORIC RESTRICTION. UNRAVELING THE MOLECULAR MECHANISMS OF RAI PRO-INVASIVE FUNCTION IN GLIOBLASTOMA DERIVED CANCER STEM CELLS IDENTIFICATION OF CRITICAL P53 CO-REGULATORS AND EFFECTORS DURING TUMOR SUPPRESSION IDENTIFICATION AND VALIDATION OF NEW THERAPEUTIC TARGETS IN ACUTE MYELOID LEUKAEMIA ,76 GR ,16 GR ,00 GR ,76 GR ,76 GR ,76 GR ,76 GR ,00 RF ,16 RF REGULATION OF MITOTIC TRANSITIONS ,16 RF l'irccs Istituto Oncologico Veneto l'irccs ISTITUTO SCIENZE NEUROLOGICHE l'irccs ISTITUTO SCIENZE NEUROLOGICHE l'irccs MAUGERI l'irccs MAUGERI l'irccs MAUGERI l'irccs MAUGERI l'irccs MEDEA AN IMAGE-ANALYSIS PLATFORM FOR AUTOMATED IN-SITU HIGH-CONTENT AND RESOLUTION ANALYSIS OF TUMOR HETEROGENEITY: TARGETING GENOMIC, EPIGENETIC, AND FUNCTIONAL DIVERSITY IN TISSUES BY FLUORESCENCE MICROSCOPY DEFINING THE CIS-REGULATORY BASES FOR VARIABILITY IN INFLAMMATORY GENE EXPRESSION IN HUMANS: A 3-D ANALYSIS IN THE NUCLEAR SPACE ANALYSIS OF THE ROLE OF DIFFERENT ISOFORMS OF THYMIC STROMAL LYMPHOPOIETIN AND THE MICROBIOTA IN T CELL ACTIVATION IN INFLAMMATORY CONDITIONS OF THE GUT TARGETING LATE RECURRENCE AFTER ADJUVANT TREATMENT FOR EARLY BREAST CANCER PROSPECTIVE CHARACTERIZATION OF CIRCULATING TUMOR CELLS IN PATIENTS WITH HORMONE RECEPTOR POSITIVE METASTATIC BREAST CANCER EARLY DIAGNOSIS, TUMOR RESPONSE TO NEOADJUVANT TREATMENTS AND DIAGNOSIS OF TUMOR RECURRENCE USING NEW AND NON-INVASIVE BIOMARKERS IN COLON AND RECTAL CANCER INDUCTION OF A SUSPENDED ANIMATION STATE BY INHIBITION OF NEURONS OF THE CENTRAL NERVOUS PATHWAY FOR THERMOREGULATORY COLD DEFENSE IN PIG "DETECTION OF PATHOLOGICAL PRION PROTEIN IN CEREBROSPINAL FLUID BY REAL-TIME QUAKING INDUCED CONVERSION (QUIC): EVALUATION AND STANDARDIZATION OF A NOVEL DISEASE-SPECIFIC LABORATORY TEST FOR THE DIAGNOSIS OF SPORADIC CREUTZFELDT-JAKOB DISEASE." BLOCKING RECIPROCAL DOWN-REGULATION OF SPHINGOSINE-1-PHOSPHATE RECEPTOR-1 AND ß1-ADRENERGIC RECEPTOR AS A NEW THERAPEUTIC STRATEGY FOR IMPROVING POST-ISCHEMIC LEFT VENTRICULAR REMODELING AND DYSFUNCTION. INHERITED ARRHYTHMIAS: CLINICAL CHARACTERIZATION, GENETIC GEOGRAPHY AND EXPERIMENTAL STUDIES IN THE CALABRIA REGION ISOLATE. STEROID MYOPATHY: PATHOGENESIS AND PREVENTION SENSORIMOTOR INTEGRATION. PHYSIOLOGY AND PATHOPHYSIOLOGY NEUROLOGICAL PERSPECTIVES ON MOTOR DEFICIT IN AUTISM SPECTRUM DISORDERS ,56 RF ,00 RF ,16 RF ,16 RF ,16 RF ,16 RF ,16 GR ,00 RF ,76 GR ,66 RF ,16 RF ,16 RF ,36 GR

10 l'irccs MEDEA l'irccs MONDINO l'irccs MONDINO WHY ME? PROJECT (WM?P). INVESTIGATING WHITE MATTER CONNECTIVITY IN SCHIZOPHRENIA AT IMAGING, CELLULAR, AND TRANSPOSONE LEVELS IN MONOZYGOTIC DISCORDANT TWINS PROTECTIVE ROLE OF HSPB8 IN MOTOR NEURON DISEASES (MNDS) NEUROMODULATION STRATEGIES TO ENHANCE THE EFFECTS OF GAIT REHABILITATION IN MULTIPLE SCLEROSIS PATIENTS WITH CEREBELLAR ATAXIA ,16 RF ,76 GR ,76 GR l'irccs MONDINO l'irccs MULTIMEDICA l'irccs NEUROLESI l'irccs NEUROLESI l'irccs NEUROLESI l'irccs NEUROMED l'irccs NEUROMED l'irccs NEUROMED A MULTICENTER PROSPECTIVE STUDY ON INFLAMMATORY/INFECTIOUS CNS DISEASES IN DIFFERENT IMMUNOLOGICAL SETTINGS: A MULTIDISCIPLINARY APPROACH USING AN ONLINE DATA BASE NONCODING RNAS AND DOXORUBICIN: ROLE OF MICRORNAS AS EARLY CIRCULATING BIOMARKERS OF CARDIOTOXICITY AND INVOLVEMENT OF SMALL AND LONG NON CODING RNAS IN DRUG-INDUCED HEART DYSFUNCTION. IMPLICATION OF MECHANOSENSING TOWARD PRO-PATHOLOGIC DIFFERENTIATION OF RESIDENT PROGENITORS IN AORTIC VALVE CALCIFICATION AND STENOSIS CYCLOPHILIN A AS A NEW THERAPEUTIC TARGET FOR LIMB ISCHEMIA BIOMARKERS OF CARDIOVASCULAR RISK AND DISEASE ACTIVITY IN PATIENTS WITH PSORIATIC ARTHRITIS: MODIFICATIONS INDUCED BY TREATMENT WITH TNF- BLOCKERS EPIGENOME WIDE PROFILING OF DYSFUNCTIONAL ENDOTHELIAL PROGENITOR CELLS IN DIABETIC PATIENTS THE ROLE OF MECHANOBIOLOGY IN ESTABLISHMENT AND PROGRESSION OF INTIMA HYPERPLASIA ASSOCIATED TO VEIN CORONARY BYPASS GRAFTS DISEASE GENDER AND GEOGRAPHICAL SPECIFIC CIRCULATING MICRORNA SIGNATURES AS BIOMARKERS OF ATHEROSCLEROSIS, ATHEROSCLEROSIS PROGRESSION AND VASCULAR EVENTS A RANDOMIZED INTERVENTION STUDY TO ASSESS THE EFFECT OF THE MEDITERRANEAN DIET ON THE PLASMA FATTY ACID PROFILE. INNOVATIVE DIAGNOSTIC APPROACH FOR HEREDITARY CARDIOMYOPATHIES APPLICATION OF MOLECULAR METHODOLOGIES INCLUDING MULTILOCUS SEQUENCE TYPING (MLST) AND MICROSATELLITE-BASED GENOTYPING TO DETERMINE THE FREQUENCY AND DISTRIBUTION OF CLINICALLY IMPORTANT CANDIDA SPECIES IN HOSPITAL CARE UNITS AND USE OF THE WHOLE GENOME M SYSTEM FOR THE AUTOMATIC ARTIFACT DETECTION AND REMOVAL FROM ELECTROENCEPHALOGRAPHIC SIGNALS ROLE OF BRAIN CONNECTIVITY IN THE DIFFERENT STAGES OF MULTIPLE SCLEROSIS ROLE OF THE GLYCOPROTEIN DICKKOPF-3 IN THE STROKE SUSCEPTIBILITY EPIDRUGS AND CARDIAC DIFFERENTIATION: RELEVANCE FOR THE 22Q11.2 DELETION SYNDROME N-ACETYLCYSTEINE IN THE TREATMENT OF NEUROPATHIC PAIN IFNGAMMA AS A POTENTIAL THERAPEUTIC TARGET IN SECONDARY HLH RISK ASSESSMENT OF ARSENIC EXPOSURE FROM RICE-BASED FOOD IN CHILDREN WITH CELIAC DISEASE: STUDY OF URINARY METABOLIC PROFILES AND GENETIC POLYMORPHISMS. L-SELECTIN DOWN-MODULATION BY HIV-1: A NOVEL HALLMARK OF INFECTION WITH POTENTIAL IMPLICATIONS FOR PATHOGENESIS NATURAL KILLER CELL-BASED IMMUNOTHERAPY FOR HIGH-RISK NEUROBLASTOMA: PHARMACOLOGICAL TREATMENT TO EFFICIENTLY IMPROVE THE EXPRESSION OF ACTIVATING LIGANDS. DELIVERY AND IMAGING OF MIRNAS BY MULTIFUNCTIONAL CARBON NANOTUBES AND CIRCULATING MIRNAS AS INNOVATIVE THERAPEUTIC AND DIAGNOSTIC TOOLS FOR PEDIATRIC PULMONARY HYPERTENSION CLINICAL AND GENETIC CHARACTERIZATION OF EARLY COMPLICATIONS IN JUVENILE OBESITY SEARCH FOR NEW GENES AND NEW THERAPIES FOR NEONATAL DIABETES MELLITUS (NDM) AND HYPERINSULINISM AND HYPOGLYCEMIA (HH) ,16 RF ,76 GR ,16 GR ,76 GR ,76 GR ,16 PE ,16 RF ,00 RF ,16 RF ,16 RF ,16 GR ,16 GR ,16 GR ,76 GR ,16 RF ,16 RF ,16 GR ,96 GR ,16 GR ,76 GR ,00 PE ,16 PE ,00 PE

11 l'irccs PASCALE l'irccs PASCALE l'irccs RIZZOLI l'irccs RIZZOLI l'irccs RIZZOLI l'irccs S.CAMILLO l'irccs S.CAMILLO l'irccs S.CAMILLO l'irccs S.D.N. l'irccs S.D.N. l'irccs S.D.N. l'irccs S.D.N. l'irccs S.D.N. l'irccs S.D.N. l'irccs SAN DONATO EXPLOITING ENDOPLASMIC RETICULUM AMINOPEPTIDASES MODULATION FOR INNOVATIVE STRATEGIES OF ANTICANCER IMMUNOTHERAPY NEXT-GENERATION SEQUENCING TO STUDY THE PENETRANCE OF DOMINANTLY INHERITED PORPHYRIAS MENINGIOMA AND VENOUS THROMBOEMBOLISM A CAPSULE ENDOSCOPY AND DOUBLE BALLOON ENTEROSCOPY SEQUENTIAL APPROACH FOR EARLY DETECTION OF GASTROINTESTINAL TUMORS IN CELIAC DISEASE: A PROSPECTIVE TRIAL TARGETING THE MYC CHROMATIN INTERACTION NETWORK IN CANCER STEM CELLS IDENTIFICATION OF COMMON PATHWAYS THAT DRIVE THE METASTATIC DISEASE THROUGH MIRNA PROFILING OF TRANSGENIC MOUSE MODELS AND HUMAN CANCERS MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF TH17 CELL POPULATIONS IN THE GUT. PROMOTING EFFECTIVE HOMECARE AND TELEMONITORING FOR PATIENTS WITH IMPLANTED DEEP BRAIN STIMULATION SYSTEMS THROUGH INTEGRATED SOLUTIONS FOR FAMILY CAREGIVERS. DEVELOPMENT OF HIGH THROUGHPUT, INTEGRATED AND COST-EFFECTIVE MOLECULAR DIAGNOSTIC TESTS FOR THE DETECTION OF GENETIC AND EPIGENETIC DEFECTS INVOLVED IN HUMAN DISEASE IMMUNE, PROCOAGULANT AND INFLAMMATORY RESPONSES IN SEVERE SEPSIS AND SEPTIC SHOCK GENOME-WIDE ASSOCIATION STUDY TO EVALUATE GENETIC RISK FACTORS FOR CEREBRAL SINUS-VENOUS THROMBOSIS (GENESIS STUDY) NEW POSSIBLE APPROACH FOR THE CLASSIFICATION OF MELANOMA AND PREDICTION OF RESPONSE TO IMMUNOTHERAPY: IMMUNOSCORE AND IMMUNE PROFILING PHASE 1/2 STUDY OF VALPROIC ACID AND SHORT-COURSE RADIOTHERAPY PLUS CAPECITABINE AS PREOPERATIVE TREATMENT IN LOW-MODERATE RISK RECTAL CANCER MULTI-SCALE MODELING FOR PREDICTIVE CHARACTERIZATION OF LIGAMENTS AND GRAFTS BEHAVIOR IN ACL RECONSTRUCTION NOVEL APPROACH FOR BONE REGENERATION AND REPAIR USING SULFUR DONOR-BASED THERAPY ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AS NEW MINIMALLY INVASIVE REGENERATIVE TREATMENT TO TARGET EARLY OSTEOARTHRITIS: FROM PRE-CLINICAL PROCEDURE SELECTION TO CLINICAL APPLICATION IN A RANDOMIZED DOUBLE-BLINDED CONTROLLED TRIAL ELECTROPHYSIOLOGICAL, BEHAVIOURAL AND FUNCTIONAL CONNECTIVITY MARKERS OF FLUCTUATING COGNITION AND ATTENTION DISORDERS IN DEMENTIA WITH LEWY BODIES AND PARKINSON S DISEASE WITH DEMENTIA MODULARITY FOR SENSORY MOTOR CONTROL: IMPLICATIONS OF MUSCLES SYNERGIES IN MOTOR RECOVERY AFTER STROKE. REGULATION OF MITOCHONDRIA-ENDOPLASMIC RETICULUM TETHERING BY PARKIN: IMPLICATION FOR PARKINSON S DISEASE GENOME-WIDE ANALYSES TO IMPROVE PROGNOSTIC AND THERAPEUTIC STRATEGIES IN NEUROBLASTOMA EVALUATION OF THE EPIGENETIC SIGNATURE IN CORONARY ATHEROSCLEROTIC LESION PROGRESSION BY CT ANGIOGRAPHY UNRAVELLING THE GLYCOSPHINGOLIPID METABOLIC CIRCUITS IN CANCER IMPACT OF INSULIN RESISTANCE AND HYPERGLYCEMIA ON MYOCARDIAL SYMPATHETIC INNERVATION AND ON DEVELOPMENT OF DIABETIC CARDIOMYOPATHY IN PATIENTS WITH PRE-DIABETES AND DIABETES MELLITUS WITH NORMAL LEFT VENTRICULAR SYSTOLIC FUNCTION. FROM PROTEIN-PROTEIN INTERACTION STUDIES NEW POTENTIAL THERAPEUTIC TARGETS TO TREAT THE MLL-RELATED ACUTE LYMPHOBLASTIC LEUKEMIAS INTEGRATED DIAGNOSTIC EVALUATION OF PET/RM AND MOLECULAR MARKERS IN THE DIAGNOSIS OF BONE LESIONS MODULATION OF HYPOXIA-INDUCIBLE FACTOR (HIF) BY SYNTHETIC PHD2 INHIBITORS: A NEW APPROACH FOR AN EFFECTIVE TREATMENT OF ISCHEMIC HEART FAILURE ,16 PE ,16 GR ,16 GR ,76 GR ,00 GR ,56 GR ,92 GR ,76 GR ,16 RF ,00 RF ,16 RF ,00 CO ,16 RF ,76 GR ,16 PE ,51 RF ,76 GR ,76 GR ,76 GR ,76 GR ,76 GR ,76 GR ,40 GR ,16 RF ,16 RF ,76 GR

12 l'irccs SAN DONATO l'irccs SAN MATTEO l'irccs SAN MATTEO l'irccs SAN MATTEO l'irccs SAN MATTEO IMPACT OF DEEP TRANSCRANIC MAGNETIC STIMULATION (TMS) ON SATIETY AND WEIGHT CONTROL EFFECT OF PROTEASOME AND VEGF RECEPTOR INHIBITORS ON NKG2D LIGAND EXPRESSION ON HEPATOCELLULAR CARCINOMA CELLS: IMPLICATIONS FOR IMMUNOTHERAPY OF LIVER CANCER. IN VITRO AND IN VIVO INVESTIGATION OF THE ORIGIN AND FUNCTION OF MALIGNANT V617FJAK2 MUTATED ENDOTHELIUM OF THE SPLEEN OF PATIENTS WITH MYELOFIBROSIS. NON-INVASIVE ASSESSMENT OF LIVER STEATOSIS AND FIBROSIS IN PEDIATRIC PATIENTS HPV POSITIVE OROPHARYNGEAL CANCER: CHARACTERIZATION OF IMMUNOLOGICAL AND VIRAL PROFILES, AND THEIR ROLE IN THE RESPONSE TO TREATMENT INVESTIGATING THE ADAPTIVE/MALADAPTIVE BALANCE IN ER-STRESS RESPONSE: INSIGHTS FROM A CMT1B NEUROPATHY MOUSE MODEL ,16 RF ,76 GR ,16 PE ,16 RF ,16 RF ,86 GR NON-CODING RNA-MEDIATED CONTROL OF HUMAN REGULATORY T CELL DEVELOPMENT, FUNCTION, AND STABILITY IN HEALTH AND DISEASE. NEUROLOGICAL AND BEHAVIORAL ABNORMALITIES IN ADENOSINE DEAMINASE-DEFICIENCY AND THEIR CORRECTION BY THERAPEUTICAL APPROACHES. THE ROLE OF IMMUNE RESPONSES AGAINST HOST MICROBIOTA IN THE MODULATION OF HOST INFLAMMTORY, METABOLOMIC AND LIPIDIC PROFILES AND IN THE PROGRESSION ATHEROSCLEROTIC DISEASE. HSC GENE THERAPY FOR LSDS: UNDERSTANDING THE MODALITIES OF CELL REPLACEMENT IN THE LSD BRAIN FOR IMPROVING THERAPEUTIC EFFICACY DISSECTING HBV IMMUNOPATHOGENESIS THROUGH THE USE OF INTRAVITAL MICROSCOPY AGE-INDUCED REDUCTION OF NEUROGENESIS INDUCES FUNCTIONAL ALTERATIONS OF THE BLOOD BRAIN BARRIER CONTRIBUTING TO THE DETRIMENTAL OUTCOME OF STROKE IN THE ELDERLY. GROWTH AND REGRESSION OF CORNEAL NEOVESSELS: PROTEOMIC AND CELLULAR FINGERPRINT. DEVELOPING INNOVATIVE TECHNOLOGICAL PLATFORMS TO IMPROVE EFFICACY AND SAFETY OF ARTIFICIAL NUCLEASES-MEDIATED GENE EDITING IN HUMAN HEMATOPOIETIC STEM CELLS. ROLE AND THERAPEUTIC TARGETING OF FOLLICULAR HELPER T CELLS IN AUTOIMMUNE DIABETES AND RHEUMATOID ARTHRITIS DOPAMINERGIC NEURONAL IN VIVO DIRECT REPROGRAMMING AS A NEW REGENERATIVE APPROACH FOR TREATING PARKINSON'S DISEASE CCR5 BASED VECTORED-IMMUNOPROPHYLAXIS IN THE PROTECTION AGAINST HIV INFECTION MULTIMODAL MAGNETIC RESONANCE IMAGING DIAGNOSIS OF FRONTOTEMPORAL LOBAR DEGENERATION (FTLD): USING SUPERVISED MACHINE LEARNING TECHNIQUES TO CLASSIFY INDIVIDUAL FTLD AND ALZHEIMER'S DISEASE PATIENTS TARGETED DELIVERY OF THE RIBOSOME-INACTIVATING PROTEIN SAPORIN FOR THE TREATMENT OF BLADDER CANCER SPINOCEREBELLAR ATAXIA TYPE 28: FROM MOLECULAR PATHOGENESIS TO PRECLINICAL TREATMENT UTX-DRIVEN GENOMIC INSTABILITY IN THE PATHOGENESIS OF MULTIPLE MYELOMA DISRUPTING THE WNT NON-CANONICAL AXIS IN MULTIPLE MYELOMA ROLE OF HMGB1 REDOX FORMS IN SATELLITE CELLS BIOACTIVITIES AND SKELETAL MUSCLE REGENERATION. EXTRASKELETAL IMPLICATIONS IN PAGET'S DISEASE OF BONE: ROLE OF P62/SEQUESTOSOME EPSINS IN EPIDERMAL NOTCH SIGNALING AND CANCER ROLE OF HIF FACTORS IN LEUKEMOGENESIS AND EVALUATION OF THE EFFECTIVENESS OF THEIR TARGETING AS ANTI-TUMOR THERAPY TIPPING THE BALANCE BETWEEN ADAPTIVE/MALADAPTIVE ENDOPLASMIC RETICULUM STRESS RESPONSES TIE2 MONOCYTE-MEDIATED DELIVERY OF IFN-ALPHA INTO THE LIVER AS A NOVEL TREATMENT FOR COLORECTAL CARCINOMA (CRC) LIVER METASTASES ,76 GR ,04 GR ,76 GR ,00 GR ,16 GR ,76 GR ,76 GR ,76 GR ,44 GR ,00 GR ,76 GR ,76 GR ,76 GR ,76 GR ,76 GR ,76 GR ,16 GR ,86 GR ,16 PE ,16 PE ,16 PE ,16 RF

13 l'irccs SAN RAFFAELE PISANA l'irccs SAN RAFFAELE PISANA l'irccs SAN RAFFAELE PISANA l'irccs SAN RAFFAELE PISANA l'irccs SAN RAFFAELE PISANA l'irccs SAN RAFFAELE PISANA l'irccs SAN RAFFAELE PISANA EVALUATION OF THE EFFICACY OF RAPAMYCIN AND A DPP-4 INHIBITOR (VILDAGLIPTIN) IN IMPROVING BETA CELL FUNCTION IN TYPE 1 DIABETES OF LONG DURATION, A PERSPECTIVE RANDOMIZED STUDY GENOMIC APPROACH FOR MOTOR NEURON DISEASES PHARMACOGENOMICS OF HYPERTENSION: A NEW APPROACH FOR A PERSONALIZED MEDICINE GENERATION AND FUNCTIONAL CHARACTERIZATION OF ARTIFICIAL LYMPHOID ORGANS WITH MUTIPOTENT STROMAL PROGENITORS A LONG NCRNA POINT-OF-VIEW TO FSHD MUSCULAR DYSTROPHY PATHOPHYSIOLOGY AND THERAPEUTICS. ROLE OF THE NOVEL PRESYNAPTIC PROTEIN PRRT2 IN NEURONAL PHYSIOLOGY AND IN THE PATHOGENESIS OF PAROXYSMAL NEUROLOGICAL DISORDERS INDIVIDUAL RISK IN CLINICALLY ISOLATED SYNDROMES OF CONVERSION TO MULTIPLE SCLEROSIS AND DISEASE PROGRESSION: AN INTEGRATED PUBLIC HEALTH CLINICAL GENOMICS APPROACH AN INTEGRATED GENOMIC, TRANSCRIPTOMIC AND EPIGENOMIC APPROACH IN MULTIPLEX MULTIPLE SCLEROSIS FAMILIES. EFFECTS OF ACTION OBSERVATION THERAPY ON REHABILITATION OF MOTOR DEFICITS OF THE DOMINANT RIGHT UPPER LIMB IN PATIENTS WITH MS: A STUDY WITH STRUCTURAL AND FUNCTIONAL MRI. NEW NANO-SYSTEMS FOR TARGETED DELIVERY OF CYTOKINES TO TUMORS DISRUPTION OF WHITE MATTER INTEGRITY IN BIPOLAR DISORDER: CHANGES OF DIFFUSION TENSOR IMAGING MEASURES AS MARKERS OF THE BIOLOGICAL UNDERPINNINGS OF THE PROGRESSIVE DETERIORATION OF COGNITION AND OF THE COGNITIVE CONTROL OF EMOTIONS. INVESTIGATION OF A NOVEL ENGINEERED PROBIOTIC TO TREAT CLOSTRIDIUM DIFFICILE INFECTION NETWORK DEGENERATION IN MOTOR NEURON DISEASES (MND): A STUDY OF THE STRUCTURAL AND FUNCTIONAL CONNECTOMES IN AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MND STRESS-ACTIVATED PROTEIN KINASES MLK3 AND P38 AS NOVEL THERAPEUTIC TARGETS IN CHEMOKINE-DRIVEN LEUKOCYTE EXTRAVASATION AND NON-RESOLVING INFLAMMATORY PROCESSES DYSREGULATED RNA METABOLISM IN MULTIPLE MYELOMA DEFECTIVE GLUCOSE METABOLISM IN POLYCYSTIC KIDNEY DISEASE DEFINES A NOVEL THERAPEUTIC STRATEGY: A PRE-CLINICAL PROOF-OF-CONCEPT STUDY NEW MOLECULAR MECHANISMS OF LEUKEMIA IMMUNE EVASION AFTER ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION ASSESSMENT OF THE MACROPHAGE ROLE IN THE NATURAL HISTORY OF MYELOPROLIFERATIVE NEOPLASMS DYNAMICS AND ULTRASTRUCTURE OF STRESS SENSING GENETIC AND LIFESTYLE FACTORS IN GASTRIC CANCER EPIDEMIOLOGY: ENHANCING RESEARCH THROUGH THE ESTABLISHMENT OF AN INTERNATIONAL CONSORTIUM DISSECTING THE ROLE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR-1ALPHA (PGC-1A) AND ADIPOSE TRIGLYCERIDE LIPASE (ATGL) IN PARKINSON'S DISEASE ACTION OBSERVATION THERAPY: A CHANCE FOR PARKINSON DISEASE PATIENTS OF IMPROVING MOBILITY THROUGH A HOME-BASED TRAINING. OVERNUTRITION AND BRAIN HEALTH IMPAIRMENT: EPIGENETIC MECHANISMS POTENTIALLY CORRELATING METABOLIC AND NEURODEGENERATIVE DISEASES DAILY AT-HOME FOLLOW-UP OF PARKINSON S DISEASE PATIENTS MOTOR PERFORMANCE THROUGH ROBOTIC AND PORTABLE DEVICES THE ROLE OF MINERALOCORTICOID RECEPTOR (MR) HYPERACTIVATION IN OBESITY: EFFECTS OF MR BLOCKADE IN HUMAN AND ANIMAL MODELS OF OVERFEEDING. HYPOXIA, INFLAMMATION AND REDOX STATUS AS DETERMINANTS OF MALIGNANT PROGRESSION OF CANCER STEM CELLS ,89 RF ,16 RF ,16 RF ,16 RF ,16 RF ,16 RF ,16 RF ,16 RF ,16 RF ,00 RF ,16 RF ,16 RF ,16 RF ,16 RF ,16 RF ,00 RF ,16 RF ,00 RF ,00 RF ,76 GR ,16 GR ,16 GR ,76 GR ,76 GR ,16 PE ,16 RF

14 l'irccs SPALLANZANI l'irccs SPALLANZANI l'irccs SPALLANZANI l'irccs SPALLANZANI l'irccs STELLA MARIS l'irccs STELLA MARIS l'irccs STELLA MARIS l'irccs AUXOLOGICO l'irccs NEUROMED CELL AUTOPHAGY MODULATION VIA ENERGY BALANCE REGULATION: AGE- DEPENDENT OUTCOMES ON INFLAMMATION, AXON REGENERATION AND NEUROPATHIC PAIN IN MURINE MODELS OF PERIPHERAL NERVE LESION. MICRORNAS DYSREGULATION ASSOCIATED WITH INFLAMMATORY SYNAPTOPATHY IN A MOUSE MODEL OF MS. BRAIN-HEART PATHWAYS TO ESSENTIAL HYPERTENSION: IS THERE A NEURAL PHENOTYPE OF CARDIOVASCULAR RISK? ROLE OF ALTERNATIVE POLYADENYLATION IN CANCER CELLS DISSECTING THE EPIGENETIC LANDSCAPE OF RHABDOMYOSARCOMA: ROLE OF P38ALPHA KINASE IN THE CONTROL OF POLYCOMB REPRESSIVE COMPLEX 2 N-TERMINAL TRUNCATED AßPE3-42 OLIGOMERS AND GLUTAMINYL CYCLASE ACTIVITY IN THE EARLY DIAGNOSIS AND CLINICAL PROGRESSION OF TYPICAL AND ATYPICAL ALZHEIMER'S DISEASE. A COHORT STUDY EXTRACELLULAR SIGNALING IN NEUROBLASTOMA THROUGH EXOSOMES FOR NOVEL DRUG TARGETS DISCOVERY (ESNET) OPTOGENETIC DISSECTION OF STRIATUM-GLOBUS PALLIDUS CONNECTION IN A MODEL OF DYT1 DYSTONIA. LOOKING FOR NEW INSIGHT ON OMEGA-3 FATTY ACIDS ROLE ON COGNITIVE DECLINE AND BRAIN DYSFUNCTIONS IN AGE-RELATED DISORDERS THE ROLE OF INFLAMMATORY CYTOKINES IN THE PATHOPHYSIOLOGY OF MOOD DISTURBANCES IN MULTIPLE SCLEROSIS RECOVERY OF PARKINSON'S DISEASE NEURONAL FUNCTIONALITY BY MODULATION OF AMBRA1, A NOVEL PRIMER OF MITOPHAGY UNRAVELING THE MYSTERY OF ALZHEIMER'S DISEASE-RELATED SYNAPTIC DEGENERATION CONNECTING MITOCHONDRIAL DYNAMICS WITH T CELL DEVELOPMENT AND TRANSFORMATION. COMBINED BEHAVIOURAL AND NON INVASIVE BRAIN STIMULATION INTERVENTIONS FOR TREATING BODY IMAGE DISTORTIONS IN ANOREXIA NERVOSA DOES GUT FLORA INFLUENCE AUTOIMMUNE RESPONSES IN MULTIPLE SCLEROSIS? THE MAIT CELL STORY. CHANGES IN STRUCTURE AND RECRUITMENT OF MUSCLE SYNERGIES AFTER CORTICAL AND CEREBELLAR LESIONS NEUROPHYSIOLOGICAL APPROACH TO EVALUATE CEREBRO-CEREBELLAR INTERACTIONS. CHARACTERIZATION OF A CEREBELLAR CONNECTIVITY EEG INDEX. MITOCHONDRIAL TARGETING IN LRRK2-ASSOCIATED PARKINSONISM (PARK8) PROMOTING MOTOR RE-LEARNING IN PATIENTS WITH STROKE BY ENHANCING NON INVASIVELY ASSOCIATED CEREBELLAR-CORTICAL PLASTICITY. MOLECULAR DISSECTION OF THE SELECTIVE AUTOPHAGIC RESPONSE TO MYCOBACTERIUM TUBERCULOSIS INFECTION CLOSTRIDIUM DIFFICILE INFECTION IN ITALY: DO WE KNOW THE TRUE MAGNITUDE OF THE PROBLEM? GENETIC VARIABILITY OF MYCOBACTERIUM TUBERCULOSIS AND ITS IMPLICATIONS FOR TRANSMISSION DYNAMICS, PATHOGENESIS AND IMMUNE RESPONSE ROLE OF IP-10 AND ITS TRUNCATED FORM IN THE PATHOGENESIS OF TUBERCULOSIS GUT TO BRAIN INTERACTION IN AUTISM. ROLE OF PROBIOTICS ON CLINICAL, BIOCHEMICAL AND NEUROPHYSIOLOGIC PARAMETERS. FRY THE BRAIN: IMPACT OF X-RAY EXPOSURE ON COGNITIVE IMPAIRMENT ACTION-OBSERVATION THERAPY (AOT) AND INFORMATION AND COMMUNICATIONS TECHNOLOGIES (ICT) FOR HOME REHABILITATION OF CHILDREN WITH HEMIPLEGIA SUDDEN CARDIAC DEATH DURING MYOCARDIAL ISCHEMIA: UNMASKING GENETIC FACTORS CONTRIBUTING TO VENTRICULAR FIBRILLATION NOVEL MARKERS BASED ON AUTOPHAGY PROTEINS IN PARKINSON'S DISEASE ,96 GR ,16 GR ,76 GR ,76 GR ,86 GR ,76 GR ,16 GR ,76 GR ,16 GR ,76 GR ,21 GR ,98 GR ,76 GR ,76 GR ,16 RF ,71 RF ,16 RF ,16 RF ,16 RF ,76 GR ,16 RF ,16 RF ,16 RF ,76 GR ,26 GR ,36 GR ,00 GR ,00 RF

15 l'izs IZSAM l'izs IZSLER l'izs IZSLER l'izs IZSLT l'izs IZSME Ministero della Salute FARM ANIMAL WELFARE AND FOOD SAFETY: EFFECT OF ON-FARM AND PRE- SLAUGHTERING STRESS FACTORS ON MICROBIOLOGICAL CONTAMINATION OF POULTRY MEAT. PRECLINICAL OPTIMIZATION OF TREATMENT WITH INHALED ARGON TO IMPROVE NEUROLOGICAL OUTCOME AND SURVIVAL AFTER CARDIAC ARREST AN EPIZOOTIOLOGICAL SURVEY OF BATS AS RESERVOIRS OF EMERGING ZOONOTIC VIRUSES IN ITALY: IMPLICATIONS FOR PUBLIC HEALTH AND BIOLOGICAL CONSERVATION DEVELOPMENT OF A RAPID, FAST AND LOW-COST ANALYTICAL KIT TO EVALUATE QUALITY AND SAFETY OF MILK AND DAIRY PRODUCTS EVALUATION OF THE POTENTIAL APPLICATION OF BIVALVE SHELLFISH AS BIOINDICATORS OF POLLUTION FOR VIRAL PATHOGENS IN COASTAL WATERS OF SOUTHERN ITALY ,76 GR ,76 GR ,76 GR ,76 GR ,16 RF l'izs IZSPB l'izs IZSPLV OMICS BIOMARKERS OF XENOBIOTIC- AND RADIATION-INDUCED OVARIAN FAILURE IN FARM ANIMALS - IMPACT ON ANIMAL PRODUCTION AND TRANSLATIONAL RESEARCH FOR HUMAN REPRODUCTIVE MEDICINE. TAKING A STEP FORWARDS THE PREPAREDNESS FOR PREVENTING CRISES: IMPROVING THE MOLECULAR DETECTION OF EMERGING PATHOGENS IN FOOD ,16 GR ,16 RF

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