Albertini Maria Cristina

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1 CURRICULUM VITAE Dr. MARIA CRISTINA ALBERTINI Personal information Surname(s) / First name(s) Address(es) Albertini Maria Cristina 22 Strada Monte Bugaro, San Costanzo Pesaro-Urbino, I Telephone(s) (39) Mobile: (39) Fax(es) (39) (s) maria.albertini@uniurb.it Nationality(-ies) Italian Date of birth Gender Female

2 Work experience Dates: Occupation or position held: Main activities and responsibilities: Name and address of employer: Type of business or sector: From November 2008 to date Full time Researcher on Medical Chemistry (MED04) Micro-RNA prediction and cancerogenesis. Research management and activity on new drugs testing for anticancer therapy. Description of the effects of Melatonin and Analogues on cell death and inflammation processes. University of Urbino, Faculty of Pharmacy, Department of Biomolecular Sciences, 2 Via Saffi, Urbino, I Website: MED04: Medical Chemistry Dates: From November 1998 to October 2008 Occupation or position held: Main activities and responsibilities: Name and address of employer. Contract Researcher and Professor Assistant either on Biochemistry and on Food Biochemistry Research management and activity on the field of consumer protection against health threats. The main research area was on environmental protection (biological effects of magnetic fields); food quality, cancer therapy. I developed an innovative image analysis technique for biomedicine (efficient health system). University of Urbino, Faculty of Pharmacy, Biological Chemistry Institute, 2 Via Saffi, Urbino, I Website:

3 Type of business or sector: Research on Biological Chemistry and innovative image analysis techniques. Occupation or position held: Main activities and responsibilities: Name and address of employer: Type of business or sector: Dates: From April 1997 to May 1997 Contract Researcher and Professor Assistant on Hydrology and Pathology. Biochemical research activity on the quality of drinking mineral water and clinical water therapy protecting citizens against health threats. University Hassan II, Ain Chock, Casablanca, Morocco Research in Biological Chemistry Dates: From February 1994 to May 1994 Occupation or position Contract Researcher held: Main activities and responsibilities: Name and address of employer: Type of business or sector: Research activity on Diabetes prevention (disease incidence reduction and therapy) Université Catholique de Louvin, Bruxelles, Belgium Research in Biological Chemistry Dates: From September 1992 to December 1993 Occupation or position Researcher held: Main activities and responsibilities: Research activity on Diabetes prevention (disease incidence reduction and therapy)

4 Name and address of employer: Type of business or sector: St. Bartholomew s Hospital, Dept. Diabetes and Metabolism, London, United Kingdom Research in Biological Chemistry Education and training: Dates: 15 April-26 October 2005 Title of qualification Certificate on New technologies. From the University awarded: to the enterprise: the research as profession. Principal subjects/occupational skills covered: Management and administration of a research projects: starting from the identification of national and international (EU projects) resources for research funding; the creation and management of a research group; the good laboratory and manufacturing practice (GLP and GMP); the creation of spin off ; the ability to identify milestones, deliverables; research management; to elaborate intermediate and final reports and audit certificates. Dates: October 1997 Title of qualification Ph.D. awarded:

5 Principal: subjects/occupational skills covered: Name and type of organisation providing education and training: Level in national or international classification: Mineral water effects on mice, rats and Humans. Biochemical and Pharmacological techniques for research activity. Science applied to public health (mineral water therapy, food biochemistry) University of Urbino Carlo Bo Level 6 (ISCD, International Standard Classification of Education) Title of qualification awarded: Dates: May 1996 Certificate on Abilitazione all esercizio della professione di Biologo Principal subjects/occupational skills covered: Clinical laboratory analysis Biochemical techniques for research activity Most relevant techniques used in biochemistry (HPLC, electrophoresis, enzyme activity, etc) Name and type of organisation providing education and training: Level in national or international classification: Ministro dell Università e della ricerca scientifica e Tecnologica, Italy Level 5 (ISCD, International Standard Classification of Education)

6 Dates: December 1993 Title of qualification First Certificate in English awarded: Principal subjects/occupational skills covered: Name and type of organisation providing education and training: English Understanding, Speaking and Writing University of Cambridge, Place of entry London, UK Dates: July 1992 Title of qualification Degree in Biology awarded: Principal subjects/occupational skills covered: Biological science Public Health (kidney disease). Name and type of organisation providing education and training: Level in national or international classification: University of Urbino Level 5A (ISCD, International Standard Classification of Education).

7 Publications 1) Albertini M.C., Canestrari F., Galli F., Galiotta P. (1992) Uptake del 86Rb negli eritrociti umani: messa a punto del metodo e delle applicazioni. Boll. Soc. Ital. Biol. Sper. 12, LXVIII: ) Galli F., Canestrari F., Pascucci M., Galiotta P., Albertini M.C., Rovidati S., Giorgini A. (1993) Metabolismo del glutatione e condizione eritrocitaria nel soggetto in dialisi extracorporea: evidenze per uno specifico meccanismo di danno ossidativo cellulare. Cardionephrology. M. Timio and W. Wizeman (Editors), Wichtig Ed., Milano. 2: ) Pascucci M., Canestrari F., Galli F., Albertini M.C., Biagiarelli B., Galiotta P. (1993) Stress eritrocitario nel trattamento emodialitico extracorporeo: effetti sul trasporto di membrana. Giornale Italiano di Nefrologia. 10 (2). 4) Beales P.E., Williams A.J.K., Albertini M.C., Pozzilli P. (1994) Vitamine E delays diabetes onset in the non-obese diabetic mouse. Horm. Metab. Res. 26: ) Canestrari F., Galli F., Giorgini A., Galiotta P., Pascucci M., Albertini M.C., Bossù M. (1994) Erythrocyte redox state in uremic anemia: Hemodialysis effects and glutathione metabolism relevance. Acta Haemat. 91 (4): ) Canestrari F., Galli F., Boschi S., Albertini M.C., Gheller G., De Crescentini S., Bossù M. (1994) Erythrocyte Na+K+-ATPase properties and adenylate energy charge in normotensive and in essential hypertensives. Clin. Chim. Acta. 224: ) Canestrari F., Buoncristiani U., Galli F., Giorgini A., Albertini M.C., Carobi C., Pascucci M., Bossù M. (1995) Redox state antioxidative activity and lipid peroxidation in erythrocytes and plasma of chronic ambulatorial peritoneal dialysis patients. Clin. Chim. Acta.234:

8 8) Beales P.E., Hawa M., Williams A.J.K., Albertini M.C., Giorgini A., Pozzilli P. (1995) Baclofen, a gamma-aminobutyric acid receptor agonist, delays diabetes onset in the non-obese diabetic mouse. Acta Diabetol. 32: ) Albertini M.C., Ghibelli L., Ricciotti R., Fumelli C., Canestrari F., Galli F., Rovidati S., Bonanno E., Fumelli P. (1996) Morphological alterations and increased resistance to haemolysis in t-butyl hydroperoxide incubated RBC from elderly subjects. Arch. Gerontol. Geriatr. suppl 5, ) Buoncristiani U., Galli F., Rovidati S., Albertini M.C., Covarelli C., Carobi C., Di Paolo N., Canestrari F. (1996) Bicarbonate versus lactate buffer in peritoneal dialysis solutions: the beneficial effect on RBC metabolism. Perit Dial. Int. 16: ) Albertini M.C., Sammartino V., Canestrari F., Baldoni F., Galli F., Rovidati S., Dachà M. (1996) Effets antioxydants du traitement hydromineral avec une eau sulfurée chez le lapin. La Presse Thermale Et Climatique.133 (2): ) Buoncristiani U., Galli F., Rovidati S., Albertini M.C., Campus G., Canestrari F. (1997) Oxidative damage during hemodialysis using a vitamin-e-modified dialysis membrane: a preliminary characterization. Nephron. 77: ) Albertini M.C., Canestrari F., Sammartino V., Rovidati S., Dachà M. (1999) Rat abreuvé d eau sulfurée: évaluation du stress oxidatif. La Presse Thermale Et Climatique. 136 (1): ) Albertini M.C., Canestrari F., Sammartino V., Rovidati S., Galli F., Ghiandoni G., Rocchi M.B.L., Dachà M. (1999) Traitement hydrominéral avec eau sulfurée chez l homme. La Presse Thermale Et Climatique. 136 (1): ) Colussi C., Albertini M.C., Coppola S., Rovidati S., Galli F., Ghibelli L. (2000) H2O2-induced block of glycolysis as an active ADP-ribosylation reaction protecting cells from apoptosis. FASEB J. 14 (14):

9 16) Albertini M.C., Soukri A., Accorsi A., Bucchini A., Said El Kebbay M.,. Ghibelli L, Piatti E., Dachà M. (2001) Glyceraldehyde-3-phosphate dehydrogenase and erythrocytes band 3 integrity as targets of hydrogen sulfide toxicity: Effect of sulfurous thermal waters. Les Cahiers de la recherche (de l'université Hassan II Aïn Chock, Maroc) 3 (1). 17) Piatti E., Albertini M.C., Baffone W., Fraternale D., Citterio B., Piacentini M. P., Dachà M., Vetrano F., Accorsi A. (2002) Antibacterial effect of a magnetic field on Serratia marcescens and related virulence to Hordeum vulgare and Rubus fruticosus callus cells. Comp. Biochem. Physiol. (B) 132, ) Albertini M. C., Teodori L., Piatti E., Piacentini M. P., Accorsi A., Rocchi M. B.L. (2003) Automated analysis of morphometric parameters for accurate definition of erythrocyte cell shape. Cytometry 52 A (1), ) Albertini M. C., Accorsi A., Citterio B., Burattini S., Piacentini M. P., Uguccioni F., E. Piatti (2003) Morphological and biochemical modifications induced by a static magnetic field on Fusarium culmorum. Biochimie (85), ) Ghibelli L., Teodori L., Cerella C., De Nicola M., D Alessio M., Clavarino G., Cordisco S., Albertini M. C., Accorsi A., Magrini A., Bergamaschi A. (2003) Jul-Sep Epigenetic role of magnetic field exposure in tumor progression: finetuning experimental models G Ital Med Lav Ergon.; 25 Suppl (3), ) Piacentini M. P., Piatti E., Fraternale D., Ricci D., Albertini M. C., Accorsi A. (2004) Phospholipase C-dependent phosphoinositide breakdown induced by ELF-EMF in Peganum harmala calli. Biochimie (86), ) Teodori L., Albertini M. C., Uguccioni F., Falcieri E., Rocchi M. B. L., Battistelli M., Coluzza C., Piantanida G., Bergamaschi A., Mucciato R. and Accorsi A. (2005) Static Magnetic Field Affect Cell Size, Shape, Orientation and Membrane Surface of Human Glioblastoma Cells, as Demonstrated by Electron, Optic and Atomic Force Microscopy. Cytometry 69 A,

10 23) Albertini M. C., Accorsi A., Teodori L., Pierfelici L., Uguccioni F., Rocchi M. B. L., Burattini S., Citterio B. (2006) Use of multiparaneter analysis for Vibrio Alginolyticus Viable but non-culturable state determination. Cytometry 69A, ) Blasa M., Candiracci M., Accorsi A., Piacentini M. P., Albertini M. C., Piatti E. (2006) Raw Millefori honey is packed full of antioxidants. Food Chemistry (97), ) De Nicola M., Cordisco S., Cerella C., Albertini M.C., D'Alessio M, Accorsi A., Bergamaschi A., Magrini A., Ghibelli L. (2006) Magnetic Fields Protect from Apoptosis Via Redox Alteration. Ann N Y Acad Sci (1090), ) Nuccitelli S., Cerella C., Cordisco S., Albertini M.C., Accorsi A., De Nicola M., D'Alessio M., Radogna F., Magrini A., Bergamaschi A., Ghibelli L. (2006) Hyperpolarization of Plasma Membrane of Tumor Cells Sensitive to Anti- Apoptotic Effects of Magnetic Fields. Ann N Y Acad Sci (1090), ) Radogna F., Paternoster L., Albertini M. C., Accorsi A., Cerella C., D'Alessio M., De Nicola M., Nuccitelli S., Magrini A., Bergamaschi A., Ghibelli L. (2006) Melatonin as an Apoptosis Antagonist. Ann N Y Acad Sci (1090), ) Albertini M. C., Radogna F., Accorsi A., Uguccioni F., Paternoster L., Cerella C., De Nicola M., D'Alessio M., Bergamaschi A., Magrini A., Ghibelli L. (2006) Intracellular Pro-Oxidant Activity of Melatonin Deprives U937 Cells of Reduced Glutathione Without Affecting Glutathione Peroxidase Activity. Ann N Y Acad Sci (1091), ) Teodori L., Accorsi A., Uguccioni F., Rocchi M. B. L., Baldoni F., Piatti E., Albertini M. C. (2007) Erythrocyte morphology automated analysis: proposal fora a new prediction tool of essential hypertension (EH) diagnosis. Cytometry B 72(3), ) Rocchi M. B. L., Sisti D., Albertini M. C., Teodori L. (2007) Current trends in shape and texture analysis in neurology: aspects of the morphological substrate of volume and wiring transmission. Brain Res. Rev. 55,

11 31) Albertini M.C., Teodori L., Conti M. E., Dachà M. (2007) Drinking mineral waters: biochemical effects and health implications the state-of-the-art. Int. J. Environmental Health 1(1), ) Radogna F., Paternoster L., Albertini M. C., Cerella C., Accorsi A., Bucchini A., Spadoni G., Diamantini G., Tarzia G., De Nicola M., D Alessio M., Ghibelli L. (2007) Melatonin antagonizes apoptosis via receptor engagement in U937 monocytic cells. J. Pineal Research 43(2), ) Coletti D., Teodori L., Albertini M. C., Rocchi M. B. L., Pristerà A., Fini M., Molinaro M., Adamo S. (2007) Static magnetic fields enhance skeletal muscle differentiation in vitro by improving myoblast alignment. Cytometry A 71(10), ) Rocchi M. B. L., Sisti D., Albertini M. C., Burroni G., Stoppioni V., Ciatti R., Burroni M. (2008) Geographical epidemiology of neonatal transitori hypothyroidism. Trend evidence in central Italian region. J. Pediatr Endocrinol Metab 21(4), ) Albertini M. C., Teodori L., Accorsi A., Soukri A., Campanella L., Baldoni F., Dachà M. (2008) Sulphurous mineral water oral therapy: effects on erythrocyte metabolism. Food Chem Toxicol 46(10), ) Moresi V., Garcia-Alvarezi G., Pristerà A., Rizzuto E., Albertini M. C., Rocchi M. B. L., Marazzi G., Assoon D., Adamo S. and Coletti D. (2009) Modulation of Caspase activity regulates skeletal muscle re generation and function in response to vasopressin and tumor necrosis factor. PLoS One 4(5):e ) Paternoster L., Radogna F., Accorsi A., Albertini M. C., Gualandi G., Ghibelli L. (2009) Melatonin as a modulator of apoptosis in B-lymphoma cells. Ann N Y Acad Sci. 1171:345-9.

12 38) Radogna F., Sestili P., Martinelli C., Paolillo M., Paternoster L., Albertini M. C., Accorsi A., Gualandi G., Ghibelli L. (2009) Lipoxygenase-mediated pro-radical effect of melatonin via stimulation of arachidonic acid metabolism. Toxicol Appl Pharmacol. 15;238(2): ) Cerella C., Cordisco S., Albertini M. C., Accorsi A., Diedrich M., Ghibelli L. (2010) Magnetic fields a pro-survival non capacitative Ca(2+) entry via phospholipase C signaling. Int J Biochem Cell Biol. 43(3): ) Albertini M. C., Olivieri F., Lazzarini R., Pilolli F., Galli F., Spada G., Accorsi A., Rippo M. R., Procopio A. D. (2011) Predicting microrna modulation in human prostate cancer using a simple String IDentifier (SID1.0) J Biom Informatics. In press. REVIEWS 1) Albertini M.C., Vasta M., Sudano M., Galli F., Stocchi O., Canestrari F., Bossù M. (1996) Assays for antibodies to Glutamate Decarboxylase. European Journal of Laboratory Medicine 4 (1),

13 Participation to Congresses 1) Galli F., Canestrari F., Albertini M.C., Pascucci M. - Haemodialysis treatment as a model for Biochemical study of red blood cell metabolic stress. Atti del congresso: ITALIAN BIOCHEMICAL SOCIETY TRANSACTION (IBST), Perugia Settembre ) Pascucci M., Galiotta P., Canestrari F., Galli F., Albertini M. C. - Concentrazione eritrocitaria e trasporto del glutatione ossidato nel soggetto uremico in trattamento dialitico extracorporeo. Atti del XXX SIMPOSIO DI NEFROLOGIA E DIALISI, Formia Settembre ) Galli F., Canestrari F., Pascucci M., Galiotta P., Albertini M.C., Rovidati S., Giorgini A. - Metabolismo del glutatione e condizione eritrocitaria nel soggetto in dialisi extracorporea: evidenze per uno specifico meccanismo di danno ossidativo cellullare. Atti del congresso: 4th EUROPEAN MEETING ON CARDIONEPHROLOGY, Assisi Marzo ) Beales P.E., Williams A.J.K., Albertini M.C., Pozzilli P. - Can Lioresal, a GABA agonist prevent diabetes in NOD mice? Atti del 12th International Immunology and Diabetes Workshop, Orlando, (Flo) ) Beales P.E., Williams A.J.K., Albertini M.C., Pozzilli P. - Free oxygen radical scavengers and their effect in protecting beta-cells in an experimental model of insulin dependent diabetes mellitus. Atti del Convegno: Molecular and cellular Biochemistry of Oxidative Stress - Urbino, Italy. September 19-22, ) Giorgini A., Rovidati S., Albertini M.C., Pozzilli P., Canestrari F.- The thiobarbiturric acid (TBA) test in fenylhydrazine (PHE) treated RBC membrane lipid peroxidation. Atti del Convegno: Molecular and cellular Biochemestry of Oxidative Stress,

14 Urbino, Italy. September 19-22, ) Galli F., Canestrari F., Giorgini A., Rovidati S, Albertini M.C., Pozzilli P. - Characterisation of specific and aspecific K+ uptake modifications in phenylhydrazine treated human RBC. Atti del Convegno: Molecular and cellular Biochemestry of Oxidative Stress, Urbino, Italy. September 19-22, ) Beales P.E., Albertini M.C., Williams A.J.K., Mansfield K.J., Canestrari F., Pozzilli P. - The influence of dietary carbohydrate on nicotinamide treatment in the non-obese diabetic (NOD) mouse. Atti del Convegno: The British Diabetic Association, Southampton 23rd-24th September, ) Albertini M.C., Fumelli P., Ricciotti R., Galli F., Rovidati S., Giorgini A., Canestrari F. - An alternative anti-gad immunoblotting assay. Atti del Convegno: Immunology of Diabetes 95 (Orvieto 31 Ottobre-3 Novembre 1995) - AUTOIMMUNITY. Vol. 21(1), (A148): ) Albertini M.C., Fumelli P., Vasta M., Ricciotti R., Signore A., Galli F., Giorgini A., Rovidati S., Sudano M., Canestrari F. - Oxidative marker in prediabetic Insulin Dependent Diabetes Mellitus subjects. Atti del Convegno: Immunology of Diabetes 95 (Orvieto 31 Ottobre-3 Novembre 1995) - AUTOIMMUNITY. Vol. 21(1), (A250): ) Buoncristiani U., Galli F., Rovidati S., Albertini M.C., Covarelli C., Carobi C., Corsi D., Pascucci M., Canestrari F. - Red blood cell redox and metabolic state in daily vs standard hemodialysis. Atti del XXXIInd Congress of European Renal Association European Dialysis and Transplant Association. Athens, June 11-14, ) Albertini M.C., Vasta M., Fumelli P., Ricciotti R., Galli F., Rovidati S., Canestrari, F. - Oxidants induced cell injury related to autoimmune Diabetes. Atti del Convegno: International Conference on Cell Death in Human Pathology. Lecce June, 1995.

15 13) Galli F., Buoncristiani U., Rovidati S., Albertini M.C. (relatore), Covarelli C., Carobi C., Corsi D., Canestrari F. - Increased membrane-bound G3PD in the RBC of uremic patients dialysed with lactate buffer. Atti del Convegno: International Conference on Cell Death in Human Pathology. Lecce 22nd-25th June, ) Canestrari F., Buoncristiani U., Galli F., Rovidati S., Albertini M.C., Covarelli C., Carobi C., Corsi D., Di Paolo N., Canestrari F. - Lactate and not bicarbonate affects erythrocyte metabolism in CAPD. Atti del Convegno: 7th Congress of The International Society for Peritoneal Dialysis. Stockholm June 18-21, ) Galli F., Buoncristiani U., Rovidati S., Albertini M.C., Covarelli C., Carobi C., Pascucci M., Galiotta P., Canestrari F.- Reduced Plasma RBC and oxidative damage in Bicarbonate versus Lactate CAPD. Atti del Convegno: 7th Congress of The International Society for Peritoneal Dialysis. Stockholm June 18-21, ) Albertini M. C. (relatore), Canestrari F., Fumelli P., Signore A., Sudano M., Vasta M. - Markers Ossidativi nel periodo precedente il Diabete Insulino- Dipendente. Atti del Congresso Regionale della Sezione Marche della Società Italiana di Diabetologia e della Associazione Medici Diabetologi, Fermo, 24 Novembre ) Buoncristiani U., Galli F., Rovidati S., Albertini M.C., Covarelli C., Canestrari F. - RBC damage indexes in home hemodialysis. Atti del Convegno della American Society of Nephrology. S. Diego (CA), 5-8 Novembre ) Galli F., Rovidati S., Albertini M.C., Buoncristiani U., Canestrari F. - RBC cell basal and stimulated K+ efflux in hemodialysis: dependence on cell age and ph. Atti del 40 Congresso Nazionale della Società Italiana di Biochimica (IBST), Torino Settembre 1995.

16 19) Albertini M.C., Sammartino V., Baldoni F., Galli F., Rovidati S., Canestrari F.- Antioxydant effect of sulfureous water. Atti del 40 Congresso Nazionale della Società Italiana di Biochimica (IBST), Torino Settembre ) Albertini M.C. (speaker), Fumelli P., Signore A., Galli F., Rovidati S., Canestrari F. - Importanza dell'enzima GST (Glutatione Transferasi) nel periodo precedente l'insorgenza del Diabete Insulino-Dipendente. Atti del Convegno: V Giornate Diabetologiche di San Giovanni Rotondo, Ospedale "Casa sollievo della sofferenza", Foggia Novembre ) Albertini M.C. (speaker), Canestrari F., Fumelli P., Signore A., Sudano M., Vasta M.. - "Markers" ossidativi nella fase prediabetica del Diabete Insulino- Dipendente. Atti del Congresso Regionale di Diabetologia, Fermo 27 Novembre ) Buoncristiani U., Galli F., Rovidati S., Albertini M.C., Covarelli C., Canestrari F. - Evaluation of the oxidative damage indexes in home hemodialysis. Atti della 16th Annual Conference on Peritoneal Dialysis, Seattle, February 21-23, ) Bucchini A.E.A., Cervasi B., Ghibelli L., Ricciotti R., Fumelli C., Albertini M.C., Fumelli P. - Oxidative damage on red blood cell (RBC) cytoskeleton. Atti del 24th Meeting of the Federation of European Biochemical Societies (FEBS), Barcelona, July 7-12, ) Albertini M.C., Canestrari F., Rovidati S., Dachà M. - Effect of sulfureous water on gyceradehyde-3-phosphate dehydrogenase. Atti del 24th Meeting of the Federation of European Biochemical Societies (FEBS), Barcelona, July 7-12, ) Albertini M. C. (speaker), L. Ghibelli, C. Colussi, Soukri A. - Meccanismi ADP-ribosilazione simili nell inibizione della GAPDH da parte dell acqua sulfurea. Atti del X Congresso Nazionale sui Processi di ADP-ribosilazione, Consorzio Mario Negri Sud, Chieti 9-10 Ottobre 1997.

17 26) Albertini M.C., Accorsi A., Bucchini A., Piatti E., Dachà M. Stress induced band-3 damage and related glyceraldehyde-3-phosphate dehydrogenase (GAPDH) avtivity on erythrocytes. Atti del Satellite Meeting to the Second practical workshop on apoptosis: Relation between biochemical and morphological events. Lecce 27 Giugno ) Albertini M. C. (speaker), Accorsi A., Bucchini A., Piatti E., Dachà M. - The effect of drinking sulfureous water on erythrocytic glyceraldehyde 3-phosphate dehydrogenase. Atti del Convegno della Sezione Toscana-Umbria-Marche della S.I.B. - Pisa 5 Giugno ) Albertini M. C., Accorsi A., Bucchini A., Piatti E., Dachà M. - Stress induced band-3 damage and related glyceraldehyde 3-phosphate dehydrogenase (GAPDH) activity in erythrocytes. Atti del Meeting Satellite The Apoptosis from the Biology to the Clinical Medicine ( Second pratical workshop on apoptosis: Relation between biochemical and morphological events )- Lecce, 27 Giugno ) Albertini M. C. (speaker), Accorsi A., Piatti E., Dachà M.- Interference of sulfureous thermal water on the interaction between erythrocyte glyceraldehyde- 3-phosphate dehydrogenase and NAD+ (NADH). Atti del Convegno della Sezione Toscana-Umbria-Marche della S.I.B. - Ancona 28 Maggio ) Albertini M. C. (speaker), Ghibelli L., Piacentini M. P., Piatti E., Rocchi M.B.L., Dachà M., Accorsi A. - Magnetic fields induce shape changes in human erythrocytes. Atti del Convegno della Sezione Toscana-Umbria-Marche della S.I.B. - Firenze 27 Maggio ) Cerella C., Coppola S., Albertini M.C., Accorsi A., Ghibelli L. Induction of calcium fluxes from endoplasmic reticulum by stimulation of phospholipase C by ADP-ribosylation inhibitors. Atti del XIV Convegno Nazionale "I processi di ADP-ribosilazione" - Urbino, Settembre 2001.

18 32) Albertini M.C. (speaker), Ghibelli L., Piacentini M.P., Piatti E., Rocchi M.B.L., Dachà M., Accorsi A. Magnetic fields induce shape changes in human erythrocytes. Proceeding of the XVIII National Meeting of the Italian Cytometry Society - Chioggia 2-5 Ottobre ) Cerella C., Mearelli C., D'Alessio M., De Nicola M., Albertini M.C., Accorsi A., Bergamaschi A., Ghibelli L. The block of glycolysis as an intracellular self-defence programme achieved via ADP-ribosylation and acting by controlling Ca 2+ fluxes. Proceeding of "Apoptosis From signaling pathways to therapeutic tools" Luxembourg 29 January-1 February ) Albertini M.C., Accorsi A., Citterio B., Piacentini M.P., Uguccioni F., Piatti E. Signal transduction pathways involved in magnetic field induced modifications of F. Culmorum conidia. Atti del 48 Congresso Nazionale della Società Italiana di Biochimica e Biologia Molecolare - Ferrara, Settembre ) Albertini M.C. (speaker), Piatti E., Uguccioni F., Rocchi M.B. L., Baldoni F., Accorsi A. Antihypertensive calcium channel antagonist drugs: preliminary studies on erythrocytes from normal subjects and therapy candidates. European Journal of Histochemistry 47/3, Proceeding of the Workshop Cell surface: from molecules to shape. Urbino, Settembre ) Albertini M.C., Accorsi A., Citterio B., Burattini S., Piacentini M.P., Uguccioni F., Piatti E. Static magnetic field induces morphological and biochemical modifications on fusarium culmorum mycelia growth. European Journal of Histochemistry (2003) 47/3, Proceeding of the Workshop Cell surface: from molecules to shape. Urbino, Settembre 2003.

19 37) Albertini M.C., Piatti E., Uguccioni F., Rocchi M. B. L., Baldoni F., Teodori L., Accorsi A. Erythrocyte morphology automated analysis: proposal for a predictive tool of essential hypertension diagnosis. Cytometry (2004) 59A, Proceedings of the ISAC XXII International Congress. Le Corum-Montpellier, May ) Luchetti F., Canonico B., Curci R., Burattini S., Battistelli M., Albertini M.C., Accorsi A., Falceri E. UV-B induced apoptosis is down-regulated by melatonin. Italian Journal of Anatomy and Embriology (2004) 109 Suppl. 1, LVIII Congresso Società Italiana di Anatomia - Chieti, Settembre ) Blasa M., Accorsi A., Candiracci M., Piacentini M.P., Albertini M.C., Piatti E. Honey phenolics protect human red blood cells against oxidative damages. The Italian Journal of Biochemistry (2004) 53, 3-Special Issue: 49 Congresso Nazionale della Società Italiana di Biochimica e Biologia Molecolare - Riccione, 27 Settembre - 1 Ottobre ) Albertini M.C., Accorsi A., Teodori L., Uguccioni F., Rocchi M.B.L., Bruscolini F., Pianetti A., Citterio B. Multiparameter analysis for Vibrio alginolyticus VBNC state determination Atti del 7 Convegno FISV (Federazione Italiana Scienze della Vita). Riva del Garda (TN) settembre ) Albertini M.C. (speaker), Cerella C., Cordisco S., Accorsi A., Bergamaschi A., D'Alessio M., De Nicola M., Nuccitelli S., Ghibelli L. Mechanisms involved in the anti-apoptotic effect of magnetic fields. Cell Signaling World 2006: Signal Transduction Pathways as Therapeutic Targets. Luxembourg January ) Cerella C., Albertini M.C., Accorsi A., Bergamaschi A., D'Alessio M., De Nicola M., Nuccitelli S., Ghibelli L. Stimulation of signal transduction by mono(adp-ribosyl)ation inhibitors: ecto- ADPRT as modulators of receptor stimulation?

20 Cell Signaling World 2006: Signal Transduction Pathways as Therapeutic Targets. Luxembourg January ) Paternoster L., Cerella C., Albertini M. C., Ghibelli L., Accorsi A. Dual, opposite effects of magnetic fields on apoptosis depending on intensity and frequency of the field. Apoptosis World 2008, Luxembourg January ) Albertini M. C., Olivieri F., Accorsi A., Rippo M. R., Spada G., Rocchi M. B. L., Galli F., Procopio A. A simple Fortran Script to identify potential mrna targets of mirna regulated by Vitamin E. SFRR Europe meeting 2009: Vitamin E Satellite Symposium (VESS). Rome 26 August 2009.

21 CURRICULUM VITAE Dott.ssa Maria Cristina Albertini Data e Luogo di nascita: Nata il 26 Giugno 1968 a Ixelles (Belgio). Residenza: Strada Monte Bugaro n 22, San Costanzo (PU). Telefono: Lingue conosciute: Francese ed Inglese (scritti e parlati) Licenza Liceale ottenuta alla Scuola Europea di Bruxelles (Woluwé), Belgio Laurea in Scienze Biologiche (106/110); titolo della tesi: Stress eritrocitario nel trattamento emodialitico extracorporeo Tirocinante e borsista presso il Department of Diabetes and

22 Metabolism dell Ospedale St. Bartholomew's di Londra (da settembre 1992 a dicembre 1993). Diploma Home Office personal licence per lavorare con gli animali di laboratorio. Diploma English first certificate per la conoscenza della lingua inglese Collaborazione con l'université Catolique de Louvin (Unité de Diabétologie et de Nutrition de l'hopital St. Luc) a Bruxelles dal febbraio 1994 a giugno Il 6 giugno 1994 ha tenuto un seminario presso la Scuola di Specializzazione in Biochimica e Chimica Clinica dell Università degli Studi di Camerino, dal titolo anticorpi contro l enzima Acido Glutammico Decarbosillasi (GAD) nella diagnosi e nella predizione del diabete Diploma di abilitazione all'esercizio della professione di Biologo ed Iscrizione all Albo Professionale con decorrenza 03 maggio Direttore del Laboratorio Analisi Chimico-Cliniche del Dott. Berardinelli & C. sito in Senigallia, via F.lli Bandiera n 58 dal 30 maggio 1996 al 30 marzo del Ha frequentato il Corso Proliferazione e morte cellulare, Scuola per le Biotecnologie e la Sperimentazione in Oncologia, che si è tenuto a Genova, Centro di Biotecnologie Avanzate (CBA), dal 10 giugno 1996 al 13 giugno 1996.