Congresso Nazionale Biomateriali SIB 2017

Transcript

1 Congresso Nazionale Biomateriali SIB 2017 Aula De Donato, Campus Leonardo Politecnico di Milano Milano, Maggio 2017

2 Comitato Scientifico Lia Rimondini Serena Bertoldi Monica Mattioli Belmonte Francesca Boccafoschi Gerardo Catapano Gianluca Ciardelli Roberto Chiesa Caterina Cristallini Elvira De Giglio Roberto De Santis Silvia Farè Pietro Favia Milena Fini Alessandro Sannino Livia Visai Segreteria Scientifica e Organizzativa Roberto Chiesa Serena Bertoldi Silvia Farè Abstract Gli abstract dei lavori sono pubblicati open- access sulla rivista internazionale Journal of Applied Biomaterials &Functional Materials fm.com/ Sponsor

3 Programma in breve Mercoledì 24 Maggio Registration Opening Invited Lecture IL1 Diego Mantovani OC1 Sandri G OC17 Demitri C Session 1 OC3 Campodoni E NANOSYSTEMS OC4 Borzenkov M OC9 Cavo M Coffee break and Poster Session OC5 Boi M Session OC6 Carniel EI MECHANICAL OC7 Villa T INVESTIGATIONS OC8 Aldieri A Assemblea dei soci SIB Giovedì 25 Maggio OC10 Borroni E Session OC11 Petrini P ADVANCED APPLICATIONS OC12 Ricci M OC13 Falvo D Urso Labate G Invited Lecture IL2 Maria Grazia Daidone Coffee break and Poster Session OC14 Fasolino I Session ADVANCED BIOMATERIALS OC15 Petta D OC16 Bollino F OC2 Cristallini C OC18 Terzi A Session 5 OC19 Ferraris S SURFACE OC20 Raffaini G MODIFICATION AND CHARACTERIZATION OC21 Colombo V OC22 Favia P

4 OC23 Liguori A Lunch OC24 La Gatta A Session OC25 Fusaro L SOFT TISSUE OC26 Degli Esposti L REGENERATION OC27 Campiglio CE F1 Faccendini A F2 Panico A F3 Miele D Fire Session F4 Saporito F F5 Stancampiano F6 Bonetti L F7 Tunesi M Coffee break and Poster Session OC28 Bloise N OC29 Bonifacio MA Session OC30 Peretti V BONE TISSUE OC37 Sartori S REGENERATION OC32 Giupponi E OC33 Altomare L Social Dinner Venerdì 26 Maggio OC34 Pressato D OC35 Bertoglio F Session ANTIBACTERIAL STRATEGIES OC36 Ruini F OC31 Rimondini L OC38 Chiesa R Invited Lecture Session 9 IL3 Coffee break and Poster Session Start up: un idea vincente? Closing session Light Lunch

5 Programma Mercoledì 24 Maggio Registrazione Apertura dei lavori Invited Lecture IL1. Nanomaterials and nanocoatings for innovation in biomaterials and health Mantovani D, Director, Lab Biomaterials and Bioengineering, CRC- Tier 1, Laval University, Canada Sessione 1 - NANOSYSTEMS OC1. Silver nanoparticles loaded electrospun nanofibers for wound healing Miele D, Sandri G, Rossi S, Bonferoni MC, Bassi B, Taglietti A, Grisoli P, Bruni G, Caramella C, Ferrari F OC17. Development of a composite material with tunable hydrophobic- oleophilic properties Calcagnile P, Caputo I, Cannoletta D, Moscatello A, Sannino A, Demitri C OC3. Innovative hybrid and intrinsically magnetic nanobeads as drug delivery system Campodoni E, Adamiano A, Dozio SM, Panseri S, Montesi M, Sprio S, Tampieri A, Sandri M OC4. Photo- thermal effect of plasmonic nanoparticles inkjet- printed on latex coated substrates Borzenkov M, Chirico G, Collini M, Sarfraz J, Ihalainen P, Pallavicini P OC9. New alginate- Matrigel composite gels allow highly metastatic breast cancer cells to maintain their aggressive behaviour in a 3D environment Cavo M, Caria M, Fato M, Scaglione S Coffee Break Sessione Poster Sessione 2 - MECHANICAL INVESTIGATIONS OC5. Nanomechanical investigation across osteochondral interface regenerated by nano- composite three- layered biomimetic scaffolds Boi M, Marchiori G, Berni M, Salamanna F, Giavaresi G,Visani A,Fini M, Filardo G, Bianchi M OC6. Computational and experimental approach to the investigation of foot plantar soft tissue mechanics Carniel El, Fontanella CG, Todros S, Pavan PG, Natali AN

6 17.45 OC7. Investigations of the surface modifications determined by the superplastic forming on titanium biomedical prostheses Palumbo G, Vedani M, Gastaldi D, Sorgente D, Piccininni A,Guglielmi P, La Barbera L, Villa T OC8. Dermis constitutive model identification from experimental strain distribution Aldieri A, Terzini M, Bignardi C, Audenino AL Assemblea soci SIB Giovedì 25 Maggio 2017 Sessione 3 - ADVANCED APPLICATIONS 8.30 OC.10 Development of engineered iron- oxide nanoparticles by lentiviral vectors for targeted cancer therapy Borroni E, Miola M, Ferraris S, Ricci G, Žužek Rožman K, Kostevšek N, Catizone A, Rimondini L, Prat M, Verné E, Follenzi A 8.45 OC11. Modelling the airway mucus microenvironment to be applied on cystic fibrosis therapy Pacheco DP, Pontremoli C, Visai L, Visentin S, Petrini P 9.00 OC12. Superparamagnetic iron- oxide nanoparticles functionalized with conjugated linoleic acid: effect on viability of mouse breast cancer cells Ricci M, Muzio G, Miola M, Ferraris S, Maggiora M, Bertone E, Puccinelli MP, Vernè E, Follenzi A, Canuto RA 9.15 OC13. Structural characterization of bovine ovarian cortical tissue and its effect on oxygen transport to follicles Catapano G, Falvo D Urso Labate G, Sudhakaran S, Rango G, Di Nardo M, Gualtieri R, Talevi R Invited Lecture 9.30 IL2. to be defined Daidone MG, Fondazione IRCCS - Istituto Nazionale dei Tumori di Milano, Dipartimento di Oncologia Sperimentale e Medicina Molecolare Coffee Break Sessione Poster Sessione 4 - ADVANCED BIOMATERIALS OC14. Eumelanin- based substrates as smart materials for neuronal regeneration Fasolino I, Raucci MG, Bonadies I, Cimino F, Soriente A, Ambrosio L, Carfagna C, Pezzella A

7 10.45 OC15. 3D printing of a tyramine- modified hyaluronic acid with a dual crosslinking mechanism Petta D, Grijpma DW, Eglin D, D Este M OC16. Applications of sol- gel materials in biomedical field: zro 2 /peg hybrid materials Bollino F, Catauro M, Tranquillo E, Vecchio Ciprioti S OC2. Micro- nano delivery systems for an efficient cystic fibrosis inflammation control Cristallini C, Barbani N, Ventrelli L, Summa C, Filippi S, Accomasso L, Vitale E, Albera C, Giachino C Sessione 5 - SURFACE MODIFICATION AND CHARACTERIZATION OC18. Wide angle X- ray scattering of different isoforms of type- I collagen: the impact of processing conditions on structural and mechanical properties Terzi A, Sibillano T, Altamura D, Salvatore L, Madaghiele M, Siliqi D, Ladisa M, De Caro L, Sannino A, Giannini C OC32. Controlling soft tissue adhesion on titanium surfaces by nanogrooves and keratin nanofibres Ferraris S, Truffa Giachet F, Varesano A, Vineis C, Cochis A, Sorrentino R, Guarino V, Iriczalli Cruz M, Ambrosio L, Warchomicka FG, Ramskogler C, Rimondini L, Spriano S OC20. Molecular dynamics study of an albumin subdomain adsorption on different crystallographic surfaces of anatase TiO 2 Raffaini G OC21. New research tools for the field of cold atmospheric plasma applications Boselli M, Capelli F, Colombo V, Gallingani T, Gherardi M, Laurita R, Liguori A, A. Miserocchi, Simoncelli E, Stancampiano A, Traldi E OC22. Effects of pam on eukaryotic cells grown on pcl scaffolds for tissue engineering Trizio I, Sardella E, Gristina R, Favia P OC23. Non- equilibrium atmospheric pressure plasma assisted functionalization of electrospun mats for the selective capture of adipose- derived mesenchymal stromal/stem cells Liguori A, Gallingani T, Gherardi M, Colombo V, Di Gesù R, Animini M, Gualandi C, Focarete ML, Dominici M, Petrachi T, Resca E, Veronesi E, Piccinno MS Pausa Pranzo - Lunch Sessione 6 - SOFT TISSUE REGENERATION OC24. Hyaluronan- based dermal fillers: the key determinants of clinical performance La Gatta A, De Rosa M, Stellavato A, Schiraldi C

8 14.45 OC25. Polylysine enriched decellularized matrices: a promising approach for vascular surgery Fusaro L, Calvo Catoira M, Ramella M, Cannas M, Boccafoschi F OC26. Improved calcium phosphate nanoparticles for targeted cardiac drug delivery Degli Esposti L, Adamiano A, Colombo P, Buttini F, Catalucci D, Iafisco M OC27. Electrospinning of a biomimetic and bioresorbable monolithic aortic valve scaffold Campiglio CE, Ponzini S, Lucherini F, Draghi L FIRE SESSION F1. Development of a thermosensitive formulation for the treatment of vulvovaginal candidosis recurrences Faccendini A, Vigani B, Rossi S, Malacrida S, Bonferoni MC, Sandri G, Caramella C, Ferrari F F2. Development of silk fibroin films for wound dressing Panico A, Paladini F, Sannino A, Pollini M F3. Scaffolds based on electrospun nanofibers for wound healing Sandri G, Bonferoni MC, Rossi S, Miele D, Saporito F, Bruni G, Boselli C, Icaro Cornaglia A, Caramella C, Ferrari F F4. Electrospun gelatin/chondroitin sulfate nanofibrous membranes for the treatment of myocardial infarction Saporito F, Sandri G, Bonferoni MC, Rossi S, Athanassiou A, Perotto G, Caramella C, Ferrari F F5. Cold atmospheric pressure plasma treatment to improve the bonding strength of dentin- adhesive system interface in dental composite restoration Colombo V, Forgione D, Gherardi M, Laurita R, Simoncelli E, Nassar M, Stancampiano A, Tonini R F6. 3D printing of methylcellulose thermo- responsive hydrogels for regenerative medicine Bonetti L, Cochis A, Sorrentino R, Contessi N, Rimondini L, Farè S F7. Collagen/hyaluronic acid- based hydrogels for the delivery of neuroprotective protein HSP70 in Parkisnon s disease Tunesi M, Raimondi I, Russo T, Cappelletti P, Fracasso R, Pollegioni L, Ambrosio L, Gloria A, Albani D, Giordano C Coffee Break Sessione Poster Sessione 7 - BONE TISSUE REGENERATION OC28. In vitro effects exerted by keratin scaffolds in combination with pemf exposure on human SAOS- 2 osteogenic differentiation Bloise N, Patrucco A, Cristofaro F, Viganò S 1, Fassina L 4, Tonin C 3, Visai L

9 17.15 OC29. PCL- reinforced hydrogel scaffolds based on gellan gum and halloysite for bone tissue regeneration Bonifacio MA, Gentile P, Ferreira AM, Altamura E, Cometa S, De Giglio E OC30. Increase in surface hardness of Ti6Al4V for application in arthroprosthetic joints Peretti V, Ferraris S, Gautier G, Hellmich C, Lahayne O, Spriano S OC37. Functional mimetics of antimicrobial peptides: novel amphipathic polyurethane to combat Gram- positive bacteria Varela P, Purkayastha S, Boffito M, Sartori S, Salber J, Ciardelli G OC19. Development and characterization of surfaces for thiol- mediated cell adhesion Giupponi E, Tana F, De Nardo L, Pezzoli D, Candiani G, Altomare L OC33. Electrophoretic deposition of chitosan/bioglass composite scaffolds with oriented micro patterns: fabrication process and in vitro biological properties GhalayaniEsfahani A, Soleimanzade M, Campiglio CE, Bonetti L, Altomare L, Draghi L, De Nardo L Social Dinner, Osteria del Treno Venerdì 26 Maggio 2017 Sessione 8 - ANTIBACTERIAL STRATEGIES 8.30 OC.34 DAC gel a hyaluronan based hydrogel antibiotic- loaded against biofilm formation: new clinical perspective in the prevention of periprosthetic joint infection Pressato D, Bellini D, Sacchetta A, Meraner J, Meani E, Romanò CL 8.45 OC35. Silver nanoparticles with pectin: ideal green biomaterial for anti- bacterial and anti- biofilm applications Bertoglio F, D Agostino A, Dacarro G, Pallavicini P, Oriano M, Cristofaro F, Bloise N, Visai L 9.00 OC36. Gelatin based nanofibers functionalized with antibacterial agents for tissue engineering applications Ruini F, Tonda- Turo C, Ceresa C, Fracchia L, Ciofani G 9.15 OC31. Bioreactor mechanically guided 3D mesenchymal stem cell chondrogenesis in a novel thermo- reversible methylcellulose- based hydrogel Cochis A, Grad S, Stoddart MJ, Faré S, Altomare L, Azzimonti B, Sorrrentino R, Alini M, Rimondini L 9.30 OC38. Bacteriostatic surface treatments for titanium implantable devices Macera G, Paroli A, Moscatelli M, Cochis A, Azzimonti B, Rimondini L, Di Giglio E, Cometa S, Chiesa R

10 Invited Lecture 9.45 IL3. Engineering approaches for the design of endovascular devices Migliavacca F, Dipartimento di Chimica, Materiali e Ingegneria Chimica G. Natta, Politecnico di Milano Coffee Break Sessione Poster Sessione 9 DALL IDEA ALL IMPRESA Start up: un idea vincente? Intervengono: Roberto Tiezzi, Capo Servizio Valorizzazione Ricerca Head, Technology Transfer Office, Politecnico di Milano Antonio Alessandrino, Silk Biomaterials S.r.l., Lomazzo, Como, IT to be defined Giuseppe Perale, Industrie Biomediche Insubri SA IBI SA, Mezzovico- Vira, CH Chiusura del Convegno SIB Light lunch

11 Sessione POSTER Nanosystems P2. Development of solid lipid nanoparticles (SLN) for intestinal lymphatic delivery: formulative studies Obinu A, Gavini E, Rassu G, Cossu M, Dionigi P, Maestri M, Giunchedi P P7. Strontium- containing nanoparticles improve bone formation Cristofaro F, Cortesi EE, Medda A, Bloise N, Bertoglio F, Visai L P13. Development of chitosan coated PLGA nanoparticles loaded with Resveratrol Miele D, Bonferoni MC, Sandri G, Rossi S, Caramella C, Ferrari F Advanced biomaterials & applications P4. Drug delivery of ampicillin from PCL- based hybrids synthesized by sol- gel processing Catauro M, Bollino F, Tranquillo E, Naviglio S P5. Inorganic phosphate and cancer: its effects in osteosarcoma, breast and pancreatic cancer cells Catauro M, Tranquillo E, Sapio L, Illiano M, Caiafa I, Naviglio S P6. Chemically crosslinked gelatin microspheres for cell delivery Contessi N, Lipreri MV, Tanzi MC, Farè S P8. Development of an experimental set- up to characterize the distribution of matter in radial flow packed bed bioreactors (rpbbs) equipped with porous hollow bioceramic scaffolds for bone tissue engineering (TE) Falvo D Urso Labate G, Barreca A, Schwentenwein M, Catapano G P10. Surface functionalization of biomaterials with natural polyphenols Ferraris S, Cazzola M, Prenesti E, Cochis A, Sorrentino R, Rimondini L, Spriano S, Vernè E P11. Tocopherol nanoemulsion stabilized with chitosan oleate: keratinocyte proliferation and spray drying to cutaneous powder Invernizzi A, Bonferoni MC, Riva F, Sandri G, Rossi S, Caramella C, Ferrari F P12. Cold atmospheric pressure plasma for the crosslinking of electrospun gelatin mats and gelatin films containing drugs Liguori A, Albertini A, Barletta F, Bigi A, Dolci LS, Focarete ML, Gallingani T, Gherardi M, Gualandi C, Miserocchi A, Oleari MC, Passerini N, Colombo V, Panzavolta S Regenerative medicine P1. Osteochondral lesions: an innovative collagen- based scaffold biomimicking tissue- specific characteristics for improved regeneration efficacy Meraner J, Beretta R, Gutleben K, Pfaller K, Bellini D WITHDRAWN

12 P3. In vivo model of guided bone regeneration in rat critical size defect with a porcine collagen membrane and a bovine bone mineral graft Ravanetti F, Calciolari E, Borciani G, Strange A, Mardas N, Bozec L, Cacchioli A, Donos P9. Micro- structural similarity of bioceramic scaffolds to human cancellous bone Falvo D Urso Labate G, Catapano G, Vitale- Brovarone C, Baino F P14. Macroporous TCP/TiO 2 scaffolds with enhanced fracture strength Preti L, Panseri S, Tampieri A, Sprio S P15. Human mesenchymal stem cells (HMSCS) effect onto primary human keratinocytes wound healing and possible regenerative applications Sorrentino R, Azzimonti B, Chiesa A, Cochis A, Squarzanti DF, Lamghari M, Rimondini L P16. Biomimetic scaffolds nanofunctionalized by molecular imprinting technology for myocardial repair Rosellini E, Barbani N, Lazzeri L, Frati C, Quaini F, Cascone MG P17. Chitosan coated alginate- based nanofibers as implantable scaffold to support axon regeneration Vigani B, Faccendini A, Rossi S, Bruni G, Sandri G, Bonferoni MC, Caramella C, Ferrari F

13 Informazioni utili Ø Il congresso si svolge presso l Aula Osvaldo De Donato, campus Leonardo, Politecnico di Milano, Piazza Leonardo da Vinci 32, indicazioni per raggiungere l aula: prendete la Metropolitana Linea 2 (MM2 Linea Verde), direzione Cologno Nord- Gessate, e scendete alla stazione di PIOLA (terza fermata). Prendete l'uscita di sinistra della stazione; seguite la via D'Ovidio fino all'incrocio con via Spinoza, tenete la sinistra e attraversate via Bonardi: a questo punto siete arrivati in piazza Leonardo da Vinci. Il Politecnico di Milano è l'edificio principale di fronte a voi fermato(mm(piola( (via(pacini)( aula(de(donato( Ø Nell aula sarà disponibile un collegamento WiFi (le indicazioni verranno fornite al tavolo della segreteria) Ø La cena sociale si terrà presso L Osteria del Treno, Via San Gregorio, 46, Milano (verranno fornite informazioni su come raggiungere il ristorante al tavolo della segreteria) per problemi di allergia alimentari o diete speciali, segnate le vostre esigenze al tavolo della segreteria al momento della registrazione Ø La segreteria sarà aperta: mercoledì 24/5 tutto il pomeriggio giovedì e venerdì: dalle ore 8.00 alle ore 9.00 e durante i coffee break e il lunch