Unmet challenges in high risk hematological malignancies: from benchside to clinical practice

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1 Turin, September 13-14, 2018 Torino Incontra Centro Congressi Scientific Board: Marco Ladetto (Alessandria) Umberto Vitolo (Turin)

2 REQUESTED AUSPICES UNIVESITÀ DI TORINO AZIENDA OSPEDALIERO-UNIVERSITARIA Città della Salute e della Scienza di Torino Presidio Ospedaliero Le Molinette SIE Società Italiana di Ematologia SIES Società Italiana di Ematologia Sperimentale FIL Fondazione Italiana Linfomi GITMO - Gruppo Italiano per il Trapianto di Midollo Osseo, cellule staminali emopoietiche e terapia cellulare Rete Oncologica del Piemonte e della Valle d Aosta FACULTY Sergio Amadori Rome - Italy Emanuele Angelucci Genoa - Italy Renato Bassan Mestre (VE) - Italy Mario Boccadoro Turin - Italy Francesc Bosch Barcelona - Spain Christian Buske Ulm - Germany Roberto Cairoli Milan - Italy Angelo Michele Carella Genoa - Italy Robert Chen Duarte - USA Annalisa Chiappella Turin - Italy Paolo Corradini Milan - Italy Francesco A. D Amore Aarhu - Denmark Matteo G. Della Porta Rozzano (MI) - Italy Brunangelo Falini Perugia - Italy Felicetto Ferrara Naples - Italy Andres J.M. Ferreri Milan - Italy Simone Ferrero Turin - Italy Gianluca Gaidano Novara - Italy Naseema Gangat Rochester - USA Michele Ghielmini Bellinzona - Switzerland Nicola Giuliani Parma - Italy Olivier Hermine Paris - France Georg Hess Mainz - Germany Marco Ladetto Alessandria - Italy Alessandra Larocca Turin - Italy Georg Lenz Munster - Germany Maurizio Martelli Rome - Italy Massimo Massaia Cuneo - Italy Vittorio Montefusco Milan - Italy Grzegorz Nowakowski Rochester - USA Fabrizio Pane Naples - Italy Francesco Passamonti Varese - Italy Stefano A. Pileri Milan - Italy Antonio Pinto Naples - Italy Patrizia Pregno Turin - Italy Alessandro Rambaldi Bergamo - Italy Giovanna Rege Cambrin Orbassano (TO) - Italy Umberto Ricardi Turin - Italy Giuseppe Rossi Brescia - Italy Stephen Schuster Philadelphia - USA Michele Spina Aviano (PN) - Italy Harald Stein Berlin - Germany Jan Trka Prague - Czech Republic Carlo Visco Vicenza - Italy Umberto Vitolo Turin - Italy Alberto Zamò Turin - Italy 1

3 THURSDAY SEPTEMBER 13, Welcome and Introduction M. Ladetto, U. Ricardi, U. Vitolo Lecture The evolving role of immunotherapy in lymphomas R. Chen Hodgkin Lymphoma and T-cell Lymphoma Chairmen: P. Corradini, U. Ricardi Histopathological and biological characterization of high risk Hodgkin Lymphoma H. Stein How I treat high risk Hodgkin Lymphoma A. Pinto Histopathology and molecular biology of T-cell Lymphoma S.A. Pileri How I treat high risk T-cell Lymphomas F.A. D Amore Mantle Cell Lymphoma Chairmen: M. Spina, C. Visco Biological identification of high risk Mantle Cell Lymphoma S. Ferrero How I treat high risk Mantle Cell Lymphoma in first line O. Hermine How I treat relapsed/refractory Mantle Cell Lymphoma G. Hess Panel Discussion Panel Discussion Lunch 2 3

4 THURSDAY SEPTEMBER 13, 2018 High Risk Aggressive Lymphoma Chairmen: M. Martelli, U. Vitolo Biological identification of high risk DLBCL G. Lenz How I treat high risk DLBCL in first line G. Nowakowski How I treat DLBCL in relapse A. Chiappella How I treat high risk extranodal DLBCL A.J.M. Ferreri Panel Discussion Chronic Lymphocitic Leukemia and Indolent Lymphoma Chairmen: M. Ladetto, G. Rossi Biology of high risk CLL G. Gaidano How I treat high risk CLL F. Bosch Biological definition of high risk FL A. Zamò How I treat high risk FL M. Ghielmini Panel Discussion Coffee Break 4 5

5 FRIDAY SEPTEMBER 14, 2018 Multiple Myeloma and Waldenström Macroglobulinemia Chairmen: M. Boccadoro, M. Massaia Biology of high risk Multiple Myeloma N. Giuliani How I treat young high risk Multiple Myeloma V. Montefusco How I treat elderly high risk Multiple Myeloma A. Larocca How I treat high risk Waldenström Macroglobulinemia C. Buske Panel Discussion Myeloproliferative Disorders Chairmen: E. Angelucci, A.M. Carella Biology of high risk myeloproliferative disorders N. Gangat How I treat high risk CML P. Pregno How I treat high risk myeloproliferative neoplasm F. Passamonti Panel Discussion Lunch Lecture CAR-T cell therapy pros and contras S. Schuster Coffee Break 6 7

6 FRIDAY SEPTEMBER 14, 2018 Acute Lymphoblastic Leukemia Chairmen: R. Cairoli, A. Rambaldi Biology of high risk ALL J. Trka How I treat high risk ALL in first line R. Bassan How I treat relapsed/refractory ALL F. Ferrara Panel Discussion Acute Myeloblastic Leukemia and Myelodisplastic Syndrome Chairmen: F. Pane, G. Rege Cambrin Genomic identification of high risk AML B. Falini How I treat high risk MDS M.G. Della Porta How I treat high risk AML S. Amadori Panel Discussion Closing remarks M. Ladetto, U. Vitolo 8 9

7 With an unrestricted educational grant of: GENERAL INFORMATION MEETING VENUE Torino Incontra Centro Congressi Via Nino Costa, Turin, Italy Tel / ITALIAN CME CREDITS An Italian CME application has been submitted as follows: Provider Studio ER Congressi SRL: ID No. 7 CME credits for Physicians (Haematology, Oncology, Internal Medicine) and Biologists. Educational objective: linee guida-protocolli-procedure. OFFICIAL LANGUAGE English BADGE AND CERTIFICATE OF ATTENDANCE All registered participants and speakers will be given a badge which they must wear to be admitted to the scientific sessions. A certificate will be given to all participants at the end of the meeting. SCIENTIFIC BOARD Marco Ladetto MD Head of Hematology Division S.S. Antonio e Biagio and Cesare Arrigo Hospital Via Venezia, Alessandria, Italy Umberto Vitolo MD Head of Hematology Division Department of Oncology University-Hospital Città della Salute e della Scienza di Torino Corso Bramante, 88/ Turin, Italy SCIENTIFIC COMMITTEE Prof. Mario Boccadoro (Turin) Prof. Gianluca Gaidano (Novara) Prof. Massimo Massaia (Cuneo) Prof. Giuseppe Saglio (Turin) ORGANIZING SECRETARIAT Studio E.R. Congressi Via Marconi, Bologna, Italy Phone Fax ercongressi@ercongressi.it struchel.com