PFIZER ITALIA S.R.L. 32.920.391 2.926.278 3.957.156 39.803.824 ASTRAZENECA S.P.A. 23.967.032 4.189.442 2.498.942 30.655.415 ROCHE REGISTRATION LIMITED 2.119.043 7.467.633 14.342.117 23.928.793 SANOFI-AVENTIS S.P.A. 14.311.757 1.385.125 1.475.708 17.172.589 GLAXOSMITHKLINE S.P.A. 11.684.358 2.418.507 2.300.253 16.403.119 JANSSEN CILAG S.P.A. 6.392.518 4.279.093 3.203.770 13.875.381 SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SPA 12.844.897 387.207 482.081 13.714.184 NOVARTIS FARMA S.P.A. 12.245.932 1.102.455 132.499 13.480.886 MERCK SHARP E DOHME (ITALIA) S.P.A. 11.626.936 16.810 53.885 11.697.631 A.MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. 10.833.588 102.542 478 10.936.609 BRACCO S.P.A. 6.515.191 668.114 2.577.641 9.760.946 ELI LILLY NEDERLAND BV 5.140.474 3.081.583 1.249.386 9.471.443 ISTITUTO FARMACOBIOLOGICO MALESCI S.P.A. 8.418.400 131.622 49.851 8.599.874 LABORATORI GUIDOTTI S.P.A. 8.076.801 73.613 50.628 8.201.043 SCHERING-PLOUGH EUROPE 1.631.592 2.147.756 4.371.751 8.151.099 MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A. 7.207.185 35.677 7.242.862 DOMPE' BIOTEC S.P.A. 1.850.076 5.183.262 112.519 7.145.856 TAKEDA ITALIA FARMACEUTICI S.P.A. 4.327.167 2.169.583 6.496.750 GLAXO GROUP LIMITED 226.059 190.319 5.957.798 6.374.175 BAYER S.P.A. 4.025.830 546.475 1.407.201 5.979.507 ITALFARMACO S.P.A. 3.877.003 1.932.236 119.367 5.928.606 BRISTOL-MYERS SQUIBB PHARMA EEIG 3.422.782 7.304 2.385.271 5.815.357 SERONO EUROPE LIMITED 1.201.284 4.291.874 300.858 5.794.016 BRISTOL MYERS SQUIBB S.R.L. 2.463.519 186.741 2.913.849 5.564.108 NOVARTIS EUROPHARM LTD 825.531 157.711 4.505.689 5.488.931 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 4.501.263 43.059 903.652 5.447.974 RECORDATI INDUSTRIA CHIMICA FARMACEUTICA S.P.A. 5.200.034 134.033 34.148 5.368.215 ABBOTT S.P.A. 3.392.440 155.460 1.586.733 5.134.633 AMGEN EUROPE B.V. 1.620.183 3.206.695 283.321 5.110.199 SANOFI PHARMA BRISTOL-MYERS SQUIBB SNC 4.718.927 292.013 5.010.940 ROCHE S.P.A. 1.372.780 994.570 2.497.001 4.864.350 ELI LILLY ITALIA S.P.A. 1.843.562 795.081 1.812.621 4.451.265 NOVO NORDISK A/S 4.326.658 93.817 771 4.421.246 WYETH EUROPA LIMITED 170.272 150.601 4.056.737 4.377.609 CENTOCOR B.V. 4.198.885 4.198.885 ABBOTT LABORATORIES LIMITED 4.021.555 4.021.555 GENZYME EUROPE B.V. 480.058 676.912 2.840.817 3.997.786 1
CHIESI FARMACEUTICI S.P.A. 3.518.287 117.321 360.654 3.996.263 ASTRAZENECA UK LIMITED 2.894.640 512.084 390.746 3.797.470 IPSEN S.P.A 1.407.423 2.185.985 150.870 3.744.278 WYETH LEDERLE S.P.A. 1.333.032 1.053.437 1.251.893 3.638.361 NEOPHARMED SPA 3.390.567 1.611 572 3.392.751 SIMESA S.P.A. 3.281.569 40.836 10.232 3.332.637 PFIZER LIMITED 2.128.916 78.726 1.057.743 3.265.386 LES LABORATOIRES SERVIER 3.005.238 33.853 3.039.090 GRUPPO LEPETIT S.R.L. 1.699.072 1.110.394 139.129 2.948.595 GILEAD SCIENCE INTERNATIONAL LIMITED 2.943.400 2.943.400 WYETH MEDICA IRELAND 2.413.391 113.272 17.706 2.544.368 ALFA WASSERMANN S.P.A. 2.009.935 436.185 89.134 2.535.254 BIOGEN IDEC LIMITED 4.725 2.430.792 2.435.517 ALTANA PHARMA S.P.A. 2.354.933 534 47 2.355.513 SCHERING A.G. 25.078 1.498.275 701.983 2.225.336 ISTITUTO GENTILI S.P.A. 2.158.608 1.709 2.160.317 IST.FARM.BIOL.STRODER S.R.L. 2.028.639 17.669 2.046.308 N.V. ORGANON 1.089.733 451.101 284.888 1.825.722 PHARMACIA ENTERPRISES S.A. 1.757.401 21.173 15.189 1.793.763 ZAMBON ITALIA S.R.L. 1.670.254 29.820 1.700.073 CHUGAI SANOFI AVENTIS 562.847 1.082.977 1.645.824 ACTELION REGISTRATION LIMITED 1.626.030 1.626.030 MERCK KGAA 360.345 1.059 1.240.596 1.602.000 PRODOTTI FORMENTI S.R.L. 1.505.238 91.609 627 1.597.473 SANOFI-AVENTIS DEUTSCHLAND GMBH 1.242.871 351.866 1.594.737 PROMEDICA S.R.L. 1.500.867 40.620 1.541.487 POLIFARMA SPA 1.475.223 8.343 1.483.566 BOEHRINGER INGELHEIM ITALIA S.P.A. 1.234.501 53.346 188.326 1.476.172 MAYNE PHARMA (ITALIA) S.R.L. 1.060 15.223 1.432.908 1.449.191 RECKITT BENCKISER HEALTHCARE LIMITED 740.378 4.242 666.236 1.410.856 LABORATORIO FARMACEUTICO C.T. S.R.L. 1.380.009 1.380.009 AVENTIS PHARMA S.A. 315.078 677 1.055.007 1.370.762 ALMIRALL S.P.A. 1.343.174 2.381 1.345.555 BAYER HEALTHCARE AG 1.336.897 6.509 1.343.406 ISTITUTO LUSO FARMACO D'ITALIA S.P.A. 1.303.375 20.376 1.323.751 H. LUNDBECK A/S 1.254.046 10.500 1.264.546 ASTRAZENECA AB 1.102.455 50.954 77.874 1.231.284 2
SCHWARZ PHARMA S.P.A 1.106.565 87.327 7.223 1.201.115 UCB PHARMA S.P.A. 1.185.642 2.136 1.187.779 MEDIOLANUM FARMACEUTICI S.P.A. 1.131.932 28.010 2.705 1.162.647 PROCTER & GAMBLE HOLDING S.R.L. 1.155.311 643 1.155.955 INDUSTRIA FARMACEUTICA SERONO S.P.A. 420.226 615.340 71.249 1.106.814 AZ. CHIM. RIUN. ANGELINI FRANCESCO ACRAF SPA 1.062.131 6.427 1.068.558 ERREKAPPA EUROTERAPICI S.P.A. 1.049.283 12.700 1.061.983 BIEFFE MEDITAL S.P.A. 1.020.434 1.020.434 INNOVA PHARMA S.P.A. 985.233 2.032 987.265 SCHERING SPA 102.028 7.650 818.899 928.578 UCB S.A. 879.686 5.597 388 885.671 SCHERING PLOUGH SPA 809.699 35.696 845.395 DAIICHI SANKYO ITALIA S.P.A. 821.933 3.798 825.731 ADDENDA PHARMA S.R.L. 807.925 3.320 811.245 MERCK SHARP & DOHME LIMITED 723.099 261 72.451 795.812 DOMPE' SPA 722.075 39.848 761.923 SOCIETA PRODOTTI ANTIBIOTICI SPA 730.378 13.890 744.268 OTSUKA PHARMACEUTICAL EUROPE LTD 422.050 320.669 742.719 FERRING S.P.A. 666.046 63.827 5.226 735.099 GE HEALTHCARE S.R.L. 715.617 715.617 F.I.R.M.A. S.P.A. 708.715 610 709.325 SANOFI-SYNTHELABO FRANCE 670.240 23.136 12.012 705.388 ALCON LABORATORIES (UK) LTD. 679.361 5.287 684.648 BRUNO FARMACEUTICI S.P.A. 599.403 61.891 661.294 SMITHKLINE BEECHAM PLC 247.568 173.039 209.424 630.031 ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI SPA 237.134 59.358 323.230 619.721 SOFAR S.P.A. 606.935 295 607.230 ALLERGAN PHARMACEUTICALS IRELAND 431.581 237 172.835 604.653 3M ITALIA S.P.A. 588.223 5.077 3.631 596.931 BIOFUTURA PHARMA S.P.A. 412.630 173.053 585.683 ASTELLAS PHARMA S.P.A. 522.030 62.193 584.223 BIOINDUSTRIA FARMACEUTICI SRL 571.902 2.961 574.862 VALEAS IND.CHIM.FARM. S.P.A. 507.448 11.451 518.898 FOURNIER PHARMA S.P.A. 513.479 393 3.468 517.339 L P B ISTITUTO FARMACEUTICO S.R.L. 507.049 2.757 509.806 CHIRON CORPORATION LTD 480.484 480.484 L. MOLTENI E C. DEI F.LLI ALITTI SOCIETA' DI ESERCIZIO 71.390 37.369 370.610 479.369 3
SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES 453.169 21.254 474.423 SOLVAY PHARMA S.P.A. 460.655 1.910 462.564 FRESENIUS KABI ITALIA S.R.L. 16.743 40.145 402.126 459.014 ABIOGEN PHARMA S.P.A. 452.687 3.548 2.213 458.448 THERABEL GIENNE PHARMA S.P.A. 422.231 22.441 7.953 452.625 MSD-SP LIMITED 442.298 9.361 451.659 ROTTAPHARM S.P.A. 446.533 2.635 449.168 TAKEDA EUROPE RESEARCH & DEVELOPMENT CENTRE LTD 209.441 193.034 402.475 THE WELLCOME FOUNDATION LTD 66.274 147.004 188.230 401.507 DOMPE' FARMACEUTICI SPA 342.432 54.105 396.537 BAXTER ONCOLOGY GMBH 11.882 322.994 56.498 391.375 APOTEX EUROPE LTD 372.964 372.964 FIDIA FARMACEUTICI S.P.A. 38.407 18 326.018 364.443 GLAXO ALLEN S.P.A. 314.204 18.787 332.991 ISTITUTO BIOCHIMICO NAZIONALE SAVIO SRL 328.748 157 328.905 PH&T S.P.A. 322.309 322.309 TEOFARMA S.R.L. 295.824 8.646 664 305.133 MASTER PHARMA S.R.L. 300.917 119 301.036 CLINTEC PARENTERAL S.A. 285.952 285.952 CRINOS S.P.A. 145.753 486 136.338 282.577 SCHARPER S.P.A. 279.378 574 279.952 ALLERGAN S.P.A. 266.632 11.284 277.916 TEVA PHARMA B.V. 21.250 31.339 213.761 266.350 PIERRE FABRE PHARMA S.R.L. 254.470 5 6.477 260.952 VALEANT PHARMACEUTICALS ITALY S.R.L. 237.129 5.623 242.752 VECCHI & C PIAM S.A.P.A. 10.814 228.695 239.509 CHIRON B.V. 232.809 232.809 TEVA PHARMA ITALIA S.R.L. 26.122 397 197.956 224.475 TEVA PHARMACEUTICALS LIMITED 2.582 202.066 204.648 INTENDIS S.P.A. 198.306 1.054 199.360 ORION CORPORATION 193.053 2.667 195.720 KYOWA ITALIANA FARMACEUTICI S.R.L. 185.264 185.264 GUERBET 182.648 182.648 MAYNE PHARMA S.R.L. 171.428 171.428 ELAN PHARMA INTERNATIONAL LTD 170.449 170.449 TYCO HEALTHCARE ITALIA S.P.A. 168.857 168.857 SOLVAY PHARMACEUTICALS B.V. 165.420 206 165.626 4
MADAUS S.R.L. 160.378 201 160.579 BIOINDUSTRIA LABORATORIO ITALIANO MEDICINALI S.P.A. 152.529 152.529 ALMIRALL PRODESFARMA S.A. 137.703 13 137.716 BAXTER S.P.A. 134.984 134.984 MUNDIPHARMA PHARMACEUTICALS S.R.L. 119.541 1.569 9.775 130.885 THERAMEX S.P.A. 130.178 47 130.226 FISIOPHARMA S.R.L. 2.918 5.688 120.918 129.524 CEPHALON UK LIMITED 107.122 17.622 124.744 SANOFI PASTEUR S.A. 119.166 119.166 MIPHARM S.P.A. 101.626 7.629 109.256 CONTINENTAL PHARMA INC 105.553 3.179 108.732 HOSPIRA S.P.A. 106.090 106.090 ITALCHIMICI S.P.A. 99.123 41 99.163 FARMACEUTICI CABER S.P.A. 96.712 27 96.739 NOVARTIS CONSUMER HEALTH S.P.A. 92.722 952 93.674 NOVASELECT S.P.A. 93.390 93.390 IPSEN LIMITED 31.605 61.295 92.900 SOLVAY PHARMACEUTICALS GMBH 86.631 415 87.046 SHIRE PHARMACEUTICAL CONTRACT LTD 85.612 85.612 IBSA FARMACEUTICI ITALIA S.R.L. 43.096 40.917 84.013 MILLENNIUM & ILEX UK LTD 83.443 83.443 FARMILA-THEA FARMACEUTICI S.P.A. 80.815 59 80.874 LABORATORIO FARMACEUTICO SIT SPECIALITA' IGIENICO TERAPEUTICHE S.R.L. 64.781 12.497 77.278 GIULIANI SPA 73.421 833 74.254 SCHWARZ PHARMA AG 70.914 70.914 GEYMONAT S.P.A. 68.315 741 69.055 ORGANON ITALIA S.P.A. 62.828 3.478 66.306 AB ANALITICA S.R.L. 65.230 65.230 LEO PHARMACEUTICAL PRODUCTS LTD 62.400 72 62.472 MERCK S.P.A. 20.202 3 41.327 61.533 LABORATOIRES 3M SANTE' 60.558 882 61.440 ZENEUS PHARMA ITALIA S.R.L. 61.432 61.432 MEDOSAN INDUSTRIE BIOCHIMICHE RIUNITE S.R.L. 58.521 4 58.524 ISTITUTO CHIMICO INTERNAZIONALE DR.GIUSEPPE RENDE 55.721 1.046 56.767 ADIENNE S.R.L. 56.536 56.536 ALCON ITALIA SPA 55.586 196 55.782 5
AFOM DIPENDENZE S.R.L. 53.713 53.713 B. BRAUN MELSUNGEN AG 53.535 53.535 S.I.F.I. S.P.A. 52.745 266 53.011 NORTON HEALTHCARE LIMITED 51.444 51.444 SO.SE.PHARM S.R.L. SOCIETA' DI SERVIZIO PER L'INDUSTRIA FARMACEUTICA ED AFFINI 4.303 0 46.056 50.359 GUILFORD PHARMACEUTICALS LTD 49.658 49.658 GALDERMA ITALIA S.P.A. 44.083 143 4.920 49.147 VALDA LABORATORI FARMACEUTICI S.P.A. 49.042 13 49.056 ISTITUTO BIOCHIMICO PAVESE PHARMA S.P.A. 47.573 47.573 ZENEUS PHARMA LIMITED 46.356 46.356 MARVECSPHARMA SERVICES S.R.L. 24.997 53 20.154 45.204 A.M.S.A. S.R.L. 44.444 689 45.133 PHARMACHEMIE B.V. 44.869 44.869 EFFIK ITALIA S.P.A. 43.875 50 43.925 EG S.P.A. 40.483 2.012 42.495 VALEANT PHARMACEUTICALS GERMANY GMBH 32.948 365 4.259 37.571 PLIVA PHARMA S.P.A. 37.222 9 272 37.503 NOVO NORDISK FARMACEUTICI S.P.A. 35.850 7 35.856 ALLEN S.P.A. 32.886 32.886 MCNEIL S.R.L. 31.645 972 32.617 ESSEX ITALIA S.P.A. 32.345 14 32.360 LIGAND PHARMACEUTICALS UK LIMITED 32.353 32.353 ABC FARMACEUTICI S.P.A. 31.770 464 32.234 LABORATORI PRODOTTI FARMACEUTICI BONISCONTRO E GAZZONE S.R.L. 31.145 1 31.147 LABORATORIO ITALIANO BIOCHIMICO FARMACEUTICO LISAPHARMA S.P.A. 2.247 2 28.875 31.124 FARMACEUTICI FORMENTI S.P.A. 30.481 4 30.485 CYANAMID OF GREAT BRITAIN LTD 29.553 29.553 KEDRION S.P.A. 1.886 5.978 21.668 29.532 MERCK PHARMA S.P.A. 28.825 25 28.850 MEDA PHARMA S.P.A. 28.577 45 28.622 INDUSTRIA FARMACEUTICA GALENICA SENESE S.R.L. 28.304 28.304 J.C. HEALTHCARE S.R.L. 22.027 5.327 27.354 MEDA A.B. 26.657 91 26.748 SANDOZ S.P.A. 518 360 25.567 26.445 6
CORTEX ITALIA S.R.L. 26.132 26.132 LUNDBECK ITALIA S.P.A. 4.674 14.791 6.595 26.061 HAMELN PHARMACEUTICALS GMBH 25.834 25.834 EBEWE ITALIA S.R.L. 25.798 25.798 ACARPIA - SERVICOS FARMACEUTICOS LDA 6.605 2 17.456 24.062 BIOPHARMA S.R.L. 24.051 24.051 ACS DOBFAR S.P.A. 23.829 23.829 MEDIMMUNE ONCOLOGY INC 21.433 21.433 CEPHALON FRANCE 20.227 472 20.700 HELSINN BIREX PHARMACEUTICALS LTD 18.956 18.956 I.BIR.N -ISTITUTO BIOTERAPICO NAZIONALE S.R.L. 18.440 2 18.441 FRESENIUS KABI DEUTSCHLAND GMBH 16.743 16.743 DOTT. FORMENTI S.P.A. 15.641 586 16.227 MEDACTA ITALIA S.R.L. 14.791 14.791 NYCOMED ITALIA S.R.L. 13.585 1.197 14.782 CIS BIO INTERNATIONAL 13.860 13.860 INCA-PHARM S.R.L. 13.326 13.326 MONICO S.P.A. 3.946 3.379 4.926 12.251 SIRTON MEDICARE S.P.A. 2.059 10.121 12.180 LABORATOIRES BESINS INTERNATIONAL 12.136 0 12.136 FARMA 1 S.R.L. 6.687 230 4.721 11.638 FAR.G.IM. S.R.L. 1.757 9.508 11.265 PIERRE FABRE ITALIA S.P.A. 10.981 48 11.028 S.F. GROUP S.R.L. 10.957 10.957 I.P.F.I. INDUSTRIA FARMACEUTICA SRL 10.755 10.755 MAX FARMA SRL 10.376 3 10.379 P.S. PHARMA S.R.L. 9.470 9.470 PANTAFARM SRL 9.383 9.383 ALFA INTES INDUSTRIA TERAPEUTICA SPLENDORE S.R.L. 9.379 9.379 PROSPA ITALIA S.R.L. 9.291 9.291 BRISTOL-MYERS SQUIBB S.A.R.L. 9.143 9.143 FERRING AB 8.160 8.160 PHARMION LIMITED 7.502 7.502 EUROGEN PHARMACEUTICALS LTD 7.097 7.097 BIOMEDICA FOSCAMA INDUSTRIA CHIMICO FARMACEUTICA 6.958 6.958 BIOPROGRESS PHARMA S.P.A. 6.931 2 6.933 LABORATOIRE AVENTIS 6.924 6 6.930 7
ISTITUTO DE ANGELI S.R.L. 5.751 1.044 6.794 LIFEPHARMA S.P.A. 6.297 10 6.308 EURO NIPPON KAYAKU GMBH 6.098 6.098 MEDIVIS S.R.L. 5.625 35 5.660 BIOCURE S.R.L. 5.552 61 5.613 LA.FA.RE. S.R.L. 5.427 1 5.428 C & G FARMACEUTICI S.R.L. 4.084 4.084 MEDOSAN RICERCA SRL 4.030 4.030 HEXAL S.P.A. 3.891 21 3.912 MONARCH PHARMACEUTICALS IRELAND LIMITED 3.696 3.696 LABORATORI BALDACCI SPA 3.554 5 3.559 JANSSEN-CILAG GMBH 3.463 3.463 PHARMATEX ITALIA S.R.L. 3.455 7 3.461 LABORATORI DIACO BIOMEDICALI S.P.A. 2.972 2.972 AMERSHAM HEALTH AS 2.561 2.561 FARMACEUTICI T.S. S.R.L. 2.350 2.350 FUJISAWA GMBH 1.918 1.918 PHT PHARMA S.R.L. 1.809 1.809 GUERBET S.P.A. 1.192 1.192 PFIZER CONSUMER HEALTH CARE S.R.L. 981 981 LAMPUGNANI FARMACEUTICI SPA 771 771 ASTELLAS PHARMA EUROPE B.V. 710 11 721 VISUFARMA S.R.L. 183 2 419 603 FARMAKA S.R.L. 510 1 511 LEVOFARMA S.R.L. 462 462 FRANCIA FARMACEUTICI INDUSTRIA FARMACO BIOLOGICA 333 333 RATIOPHARM GMBH 233 233 GENETIC S.P.A. 117 117 ANGENERICO S.P.A. 49 31 80 NEW.FA.DEM. S.R.L. 78 78 OFFICINA FARMACEUTICA FIORENTINA S.R.L. 12 12 FRESENIUS KABI ITALIA S.P.A. 2 2 SOCIETA' STABILIMENTO CHIMICO FARMACEUTICO MENDELEJEFF S.R.L. 2 2 DEPO-FARMA S.R.L. 1 1 SALUS RESEARCHES S.P.A. 1 1 FARMACEUTICI ECOBI SAS 1 1 8
311.184.857 66.912.133 101.850.542 479.947.532 9