CURRICULUM VITAE ET STUDIORUM

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1 CURRICULUM VITAE ET STUDIORUM 1 Dr. Luigi Ambrosio Director and Professor of Biomaterials Institute of Composite and Biomedical Materials, National Research Council, Piazzale Tecchio 80, Naples, Italy. PERSONAL INFORMATION Born, 21 February, 1955, S. Giuseppe Vesuviano, Naples, Italy. Status: Married, 2 children. Citinzeship: Italian. Addresses Home: Via G. Leopardi 38, Ottaviano, Naples, Italy. Telephone: Office: Institute of Composite and Biomedical Materials, (IMCB-CNR), Piazzale Tecchio 80, Naples, Italy. Telephone: , , Fax: ; Mobile: , ambrosio@unina.it. EDUCATION 1982 Doctoral Degree in Chemical Engineering, University of Naples, Italy. EXPERIENCE Research Associate at Department of Materials and Production Engineering, University of Naples Visiting Scientist at Kontron Medical Inc., 9 Plymouth Street, Everett, MA, USA Research Associate at Department of Chemical Engineering and Institute of Materials Science, Polymer Program, University of Connecticut, Storrs, CT, USA Research Associate at Department of Materials and Production Engineering, University of Naples, Italy Principal Research Scientist at Kontron Medical Inc., 9 Plymouth Street, Everett, MA, USA , Research Scientist at Institute of Composite Materials Technology, CNR, Piazzale Tecchio 80, Naples, Italy , Senior Research Scientist at Institute of Composite Materials Technology, CNR, Piazzale Tecchio 80, Naples, Italy Today, Appointed Professor of Biomaterials, University of Naples Federico II.

2 , Adjunct Professor at Institute of Materials Science, University of Connecticut, Storrs, CT, USA Today Research Director at Institute of Composite and Biomedical Materials, (IMCB- CNR), Piazzale Tecchio 80, Naples, Italy Director of the Institute of Composite and Biomedical Materials, (IMCB-CNR), Piazzale Tecchio 80, Naples, Italy Today Director of the Institute of Composite and Biomedical Materials, (IMCB-CNR), Piazzale Tecchio 80, Naples, Italy. PROFESSIONAL SOCIETIES Societa' Italiana di Biomeccanica in Ortopedia e Traumatologia (SIBOT) (Council member ) Societa' Italiana Biomateriali (SIB) (Council member since 2001, Vice-President since 2005) Associazione Italiana Macromolecole (AIM) European Society of Biomaterials (ESB) (Council member since 1997, Treasurer , President since Sept. 15, 2007) European Society of Biomechanics (ESB) Bio/Enviromentally Degradable Polymer Society (BEDPS) Gruppo Interdivisionale Biomateriali della Società Chimica Italiana (GIB-SCI) (Council member since 2000, President since 2003) American Chemical Society (ACS) EDITORIAL ACTIVITIES Editorial Board Biomateriali Guest Editor of Biomaterials Journal, Vol.15,N.15, December Editorial Board of Polymer International Journal, from 1995 Editorial Board of Journal of Biomedical Materials Research, from Guest Editor di Polymer International Journal, Polymers for Biomedical Applications Vol.46, N.3, July Guest Editor of Journal of Materials Science: Materials in Medicine, Oct/Nov Associate Editor of Journal of Applied Biomaterials & Biomechanics, from 2003 Editorial Board of Biomacromolecules Journal, from Editorial Board di Biomaterials Journal, from Guest Editor of Journal of Materials Science: Materials in Medicine, Dec Honor Committee, Journal of Intercultural and Interdisciplinary Archaeology, April Contributing Author of Vision Paper and Basis for a Strategic Research Agenda for NanoMedicine. European Technology Platform on NanoMedicine Nanotechnology for Health. VII EU Framework Program. September Reviewer of Tissue Engineering Journal, Mechanical Engineers Journal, Journal of Materials Science and Engineering C, Acta Biomaterialia, Journal of Biomaterials Applications, Journal of Biomaterials Science Polymer Editio n, Journal of Bioactive and

3 Compatible Polymers. 3 PROFESSIONAL ACTIVITIES Grants/Funding The development of improved biocompatible materials for urological and other Medical Devices. Brite-Euram, BRE2-CT Role: Partner. Sostituzioni Funzionali, Organi Artificiali e Trapianti di Organo, Nuovi poliuretani per ventricoli artificiali e relative tecnologie di preparazione. Istituto Superiore di Sanità, Role: Partner. Bioactive phospholipid-based osteointegrative orthopaedic biomaterials. Brite-Euram, BRPR-CT Role: Partner. Design, preparation and characterization of composite tendon and ligaments. Progetto Finalizzato MSTA II, sottoprogetto Biomateriali, Ortopedia , Role: Partner. Improvement of dental implant osteointegration by surface modification and design of composites structures. Progetto Finalizzato MSTA II, sottoprogetto Biomateriali, Odontoiatria Role: Coordinator. Hybrid bio-artificial ligament and tendon reconstruction devices prepared by combining synthetic and natural materials with tissue engineering techniques. Brite-Euram,BRP-CT Role: Partner. Synthesis and Characterization of vitreus substitute. Bilatelar research project CNR(Italy)- CSIC (Spain) Role: Partner. Composites hydrogels for orthopaedic applications. P.O.P., Azione5.4.2, Annualità 1998, Regione Campania "Hyaluronic acid Collagen composite scaffolds for tissue regeneration" Legge Regionale , n.41, Biomaterials and related applications, Ministero della Ricerca Scientifica Composite scaffolds fo bone tissue engineering. MIUR, FIRB RBAU01N79B Structural materials for biomedical applications, MIUR-Fondo special per lo sviluppo della ricerca di interesse strategico Role: Partner. Novel intervertebral disc prostheses FP5, G5RD-CT , Role: Coordinator,. Innovative materials and technologies for a bio-enginnered meniscus substitute, FP5, GRD1-CT , Role: Partner. Bioactive candyes and chew-gums. Indaco S.p.A., Caivano, Napoli Development of composites calcium-phosphates based biomaterials. FinCeramica s.r.l., Faenza A System Approach to Tissue Engineering Processes and Products (STEPS). FP6- IP, NMP3-CT Role: Partner & WP leader. Injectable Macropourus Biomaterials based on Calcium Phosphates Cements for Bone Regeneration. FP6- STREPS, SMARTCaP. NMP3-CT Role: Partner. Mechano-active tissue engineering of tendon and heart valves. Bilatelar research project IMCB-CNR (Italy) - GIST (Soouth Korea), Ministry of Foreign Affair TissueNet, MUR-FIRB RBPR05RSM Role: Coordinator. Materiali Innovativi per lo sviluppo di bioprotesi articolari MUR-FIRB RBIP068JL9, Role: Partner. Bioactive chew-gums loaded with vegetal biomolecules. Indaco S.p.A., Caivano, Napoli.

4 Conference Chairman/Organizer "USA-Italy Joint Workshop on Polymers for Biomedical Applications", June 11-16, 1989, Capri, Italy. Giornate di Studio sui Biomateriali Progetto Finalizzato MSTA, 7-10 Ottobre 1990, Capri, Italy. "International Conference on Advances in Fiber Reinforced Composites Technology, June , Capri, Italy. "International Conference on Materials for Biomedical Applications", Giugno 6-11, 1993, Capri, Italy. International Conference on Advances in Biomaterials and Tissue Engineering, Giugno , Capri, Italy. International Conference on Advances in Biomaterials and Regenerative Medicine, Giugno , Capri, Italy. European Conference on Biomaterils-ESB2005, Settembre 2005, Sorrento, Italy. Consensus Meeting on Biomaterials, Settembre 2005, Sorrento, Italy International Conference on Advances in Biomaterials for Drug Delivery and Regenerative Medicine, Giugno 11-16, 2006, Capri, Italy. Italian Conference on Biomaterials and Regenerative Medicine, GIB-SIB September 2006, Vico Equense, Naples, Italy. Teaching & supervising activities Appointed Professor of Biomaterials, Università degli Studi di Napoli Federico II. Adjunct Professor of Biomechanics, Scuola di Specializzazione in Medicina Fisica e Riabilitazione della Facoltà di Medicina and Chirurgia dell Università di Napoli.( ). Short teaching courses: - "Biomateriali", Centro Interuniversitario di Ricerca in Materiali per l'ingegneria Biomedica, Fiè allo Sciliar (BZ) Italy, 15-18/3/ "Biomateriali, Tecnologie, Trasferimento Industriale Centro Interuniversitario di Ricerca in Materiali per l'ingegneria Biomedica, Isola d'elba, 22-26/6/ Biocompatibilità: Aspetti Biologici e Clinici, Centro Interuniversitario di Ricerca in Materiali per l'ingegneria Biomedica, Isola d Ischia, 1-4/7/ "Impianti Protesici: Biomeccanica e Biomateriali Centro Interuniversitario di Ricerca in Materiali per l'ingegneria Biomedica and SIBOT, Ischia, 14-19/7/ Biomateriali: Biocompatibilità e Bioattività Gruppo Nazionale Cibernetica e Biofisica, Marcelli di Numana, Ancona, September, Nuovi Materiali per Cementi Ossei al V Corso Nazionale Biocompatibilità dei Dispositivi Medici Impiantabili: Interazione dei Sistemi Biologici con i Biomateriali, Istituto Superiore di Sanità, Roma, Novembre, Materiali Compositi come Biomateriali e nel Settore Dentale, PASTIS-CNRSM, Brindisi, 18 Maggio Materiali per applicazioni biomedicali», Corso di Perfezionamento in Tecnologie Innovative per la Preparazione di Materiali Inorganici, Bologna, 1 Giugno 1998.

5 - Composites as Implant al Full-day Workshop sponsored by PMSE Division of American Chemical Society, 23 Agosto 1998, Boston, MA, USA. - "Biomateriali: Scienza, Tecnologie, Biocompatibilità» Centro Interuniversitario di Ricerca in Materiali per l'ingegneria Biomedica, Bonassola (SP), Settembre Tissue Engineering, Biomaterials PhD Program Universitat Politecnica de Catalunya, Giugno 2004, Barcelona, Spain. - Biodegradable Polymers, Summer School on Biomaterials in Orthopaedics and Dentistry, 2-6, May 2005, Bologna, Italy - Meccanismi di migrazione cellulare in strutture complesse XXIV Scuola Annuale: Biomateriali: Dagli Impianti Protesici alla Medicina Rigenerativa, Settembre 2005, Bressanone, Italy. - Composite Biomaterials, Biomaterials in Medicine Course, September 17, 2006,Vico Equense, Naples, Italy. - Biocomposites, Biomaterials in Medicine Course, May 29, 2007, Bologna, Italy. Supervisor of students thesis degree at the Department of Materials and Production Engineering, University of Naples FedericoII. Supervisor of PhD students at the Department of Materials and Production Engineering, University of Naples FedericoII. Supervisor of students thesis degree at Medicine and Surgery Faculty, Università Cattolica del Sacro Cuore, Facoltà di Medicina e Chirurgia A. Gemelli, Roma, Italy. 5 Invited Lectures "Recent Advances in Biomedical Polymers", Institute of Materials Science, University of Connecticut, Storrs, USA, 2/11/1994. "The Use of Composite Materials in Medical Applications", Mount Holyoke College, South Hadley, MA, USA, 3/11/1994. "Synthetic Polymers for Biomedical Applications as Ligaments", University of Gent, Belgium, 29/3/1995. "Composite Hydrogels for Implants", Institute of Materials Science, University of Connecticut, Storrs, CT, USA, April Rheological Properties of Hyaluronic Acid Based Solution Division of Polymeric Materials Science and Engineering, American Chemical Society, Agosto 1998, Boston, MA, USA. Composite Materials for Biomaterials and Prostheses Design, 5th International Symposium on Applied Bioinorganic Chemistry, April 1999, Corfù, Greece. Design and Properties of Composite Scaffolds for Tissue Engineering, 3rd International Symposium on Frontiers in Biomedical Polymers Including Polymer Therapeutics, May 1999, Shiga, Japan. Design of biomaterials following nature s guidelines, The Italian Science Seminar at the Italian Embassy in the United Kingdom, 7 July 1999, London, U.K.. Advances in Hydrogels for Soft Tissue Implants, Euromat 99, September 1999, Munchen, Germany. Idrogeli Compositi per Applicazioni Biomediche, II Convegno Nazionale sulla Scienza e Tecnologia dei Materiali, Acireale (CT), Ottobre 14-16, Rheological properties of Biological fluids and Related Substitutes, Istituto de Ciencia y Tecnologia de Polymeros, CSIC Madrid, Spain, 15 Dicembre "Bio-analogue Materials for soft tissue replacement", I Congreso Iberico de Biomateriales y

6 Biosensores. Avila, 15 September 2000, Spain. "Advances on Hydrogels and Composites for Soft Tissue Implants", Poly Millennial Big Island, Haway December 2000, USA. "Bio-analogue Materials for tissue replacement", Fourth International Symposium on Frontiers in Biomedical Polymers, Williamsburg, Virginia, USA, May 16-19, Polymer Biomaterials in Reconstructive Surgery: From gels to composite structures. 3 rd Advanced Course in Biomaterials: Cell-Material Interactions. July 1-5, 2002, Porto, Portugal. Biofunctional Materials for Tissue Reconstruction, Gels, genes, Grafts & Giants Symposium, Maui, USA, December 17-20, Scaffold biodegradabili, Bionova 2003, Padova 4-6 Giugno 2003 Biofunctional Materials for Tissue ReconstructionEuropean Polymer Federation Conference, Stocholm, Sweden June 23-27, Bioactive Composites And Gels As Scaffolds For Tissue Regeneration Frontiers in Biomedical Polymers, Ischia September, Biomaterials Structures and Tissue Engineering Arab Conference of Biophysics, Cairo Egypt August Biomimetic hydrogels for tissue reconstruction, E.MRS-Fall Meeting, Warsaw, Poland, September 15-19, Biomimetic hydrogels for implants and tissue engineering scaffolds design, XVI Confegno Italiano di Scienza e Tecnologia delle Macromolecole, Pisa September Composite materials for Biomedical Applications, 2 nd Brazil-MRS Meeting, Rio de Janeiro, Brasil October, Materiali bioattivi per l ingegneria tissutale dello scheletro, VI Congresso Nazionale della Italian Orthopaedic Research (IORS), Bologna Aprile, 2004 Polymer Composites As Scaffolds For Tissue Engineering, 7th World Biomaterials Congress, Maggio, Sydney, Australia, 2004 Biomimetic structure for implants and tissue engineering. Internationa Conference on Biomaterials and Tissue Engineering, Kuala Lampur, May Composite scaffolds for skeletal tissue engineering, 10 th International Conference on Polymers in Medicine and Surgery, PIMS04, 6-8 September, Cambridge, UK. Ingegnirizzazione di scaffolds per l ingegneria dei tessuti, Past, present and future, traguardi e prospettive nella ricerca sui biomateriali, Napoli 21 Settembre, Composite technology to design tissue engineering scaffolds, Ceramic, Cells and Tissues: Materilas for Tissue Engineering, Sept. 28- October 1, 2004, Faenza, Italy Bioactive scaffolds for tissue engineering, Fifth International Congress on Progress in Bioengineering and the Vascular Endothelium basic: Basic and Clinical Aspects October, 2004 Pisa, Italy. Proprietà meccaniche e morfologiche di un sostituto osseo iniettabile in materiale composito. Congresso Italiano di Ortopedia e Traumatologia SIOT Ottobre, Bio-inspired structures for implants and tissue engineering, International Conference on Biomaterials and Medical Devices. 4-7, November, 2004, Bucharest, Romania. Polymers and composites scaffold for connective tissue regeneration, Symposium on Maniscus: state of art, allograft, repair, tissue engineering. Medical University of Vienna, Vienna November 26, Polimeri e compositi in medicina rigenerativa, Centro di Cultura per l Ingegneria delle Materie Plastiche Politecnico di Torino, Sede di Alessandria, 13 May, 2005, Italy. Biomimetic approach in developing the intervertebral disc prostheses, 2nd World Congress on Regenerative Medicine,May 18-20, 2005, Leipzig, Germany. A quando l osso di sintesi? I biomateriali e l osso: panoramica. Consensus Conference,

7 settembre Holiday Inn Resort Castelvolturno, Naples, Italy Composite and gels for skeletal tissue regeneration, National University of Galway, Ireland, April 20, Biomateriali compositi per la rigenerazione dei tessuti connettivi, Research to Business, 2nd Exhibition-Conference on Industrial Research, Bologna 11/12 Maggio Dal Laboratorio all impresa: il passo lento degli spin off accademici, Research to Business, 2nd Exhibition-Conference on Industrial Research, Bologna 11/12 Maggio Acellular and Cellular Scaffolds for Connective Tissue Regeneration University of Gent, Belgium, 31 May Biomimetic Hydrogel for Tissue Reconstruction. 11th International Ceramic Congress, 4th Forum on New Materials, CIMTEC June 4-9, 2006, Acireale, Catania, Italy. Polymer based biomaterials: from tissue repair to tissue regeneration. Symposia Biomaterials for a better life. Eurobio2006, October 25-27, Paris, France. Bioactive scaffolds for connective tissue regeneration, International Conference on Biomaterials and Medical Device-BiomMed2006. November 9-11, 2006, Iasi, Romania. Biomateriali compositi per la riparazione e rigenerazione dei tessuti connettivi. Giornata franco-italo-monegasco. Montecarlo, 5 December Bioactive polymer based scaffolds for tissue engineering, 7th International Symposium on Frontiers in Biomedical Polymers, June Ghent- Belgium. Polymer scaffolds for connective tissue regeneration, Biological sufaces and Interfacies, European Science Foundation Research Conferences, 1-4 July, 2007, Sant Feliu de Guixos, Spain. Polymer based biomaterials: from tissue repair to tissue regeneration. Italian Embassy in Seoul, GIIST-Gwangju, 29 August Boactive polymer based materials for tissue reconstruction. Bioingeneering and Nanomedicine Symposium 07, Institut de Bioenginyeria de Catalunya (IBEC), Barcelona, 7 Novemeber Composite hydrogels and gels for tissue regeneration, International Congress on Biohydrogels, November, Viareggio, Italy. Matrici sintetiche per la rigenerazione dei tessuti, 92 Congresso Nazionale della Società Italiana di Ortopedia e Traumatologia, SIOT 2007, November 2007, Bologna, Italy. 7 Advisory Scientific Board/Committee Technology District on Engineering of Polymer Composites and Structures - IMAST Scarl., Portici, Naples. Since 2002 Centro di Competenza Nuove Tecnologie per attività Produttive, Regione Campania, Napoli. Since Dipartimento Progettazione Molecolare del CNR. 14/09/ /08/05. Progettazione mirata di macromolecole con proprietà strutturali, di barriera e di biocompatibilità e di materiali micro e meso porosi con proprietà di trasporto del Dipartimento Progettazione Molecolare del CNR Biomateriali ed Ingegneria dei Tessuti, IMCB-CNR Academica Life Science srl, Naples, Italy. Since European Commission Advisory Group of the FP7 theme Nanoscience, Nanotechnologies, Materials and New Production Technologies. Since 2006.

8 8 Awards and honors Archi.Med Award for the most innovative research in biomaterials and medical devices. University of Bari e Fiera del Levante, 24 Febbraio, Fellow of the American Institute for Medical and Biological Engineering (FAIMBE), 1/03/2001 Fellow of Biomaterials Science and Engineering. (FBSE) of the IUS-BSE (International Union of Societies for Biomaterials Science & Engineering). 1/03/2004. Honorary Member, The Romanian Society for Biomaterials, Nov Reviewer, Evaluation committee and Ph.D Thesis Dissertation Panels European Commission, Directorate General XII, Science, Research and Development, Brussels National Agencies MIUR, MAP, FAR, PIA, INFM, PNR, Regione Emilia Romagna, Fondazione Cassa di Risparmio di Trento e Rovereto. Fundacao para a Ciencia e a Tecnologica, Ministerio da Ciencia e a Tecnologia, Ministerio da Ciencia e do Ensino Superior, Portugal. University of Gent and ITB2B French Program. Engineering and Physical Science Research Council, U.K.. Queen Mary & Westfield College, University of London, Settembre 1998, U.K. University of Cairo, Faculty of Science, Agosto 1999, Egypt. University of Tampere, 1 December Universitat Politecnica de Catalunya, Barcelona. Spain, University di Twente, The Netherland, 10 December Università di Lund, Sweden, 10 December 2003 University of Gent, lecturer nomination/appointment in Polymer chemistry & Biomaterials, 30 May Universitat Politecnica de Catalunya, Barcelona, Spain, 17 September 2007.

9 PUBLICATIONS IN PEER-REVIEWED JOURNALS 9 International Journals 1. P.A. Davis, L. Nicolais, L. Ambrosio, S. J. Huang, "Synthesis and Characterization of Semiinterpenetrating Polymer Network of Poly-(2-hydroxyethylmethacrylate) and Poly- (caprolactone). ACS - Polymeric Materials Science and Eng., 56, , ISSN: ; ISBN P.A. Davis, L. Nicolais, L. Ambrosio, S.J. Huang, "Poly(2-hydroxyethylmetacrylate)/Poly(ecaprolactone) Semi -interpenetrating Network ". Journal of Bioactive and Compatible Polymers, Vol. 3, pp , ISSN: G. Peluso, L. Ambrosio, M. Cinquegrani, L. Nicolais, S. Saiello, G. Tajana, "Rat Peritoneal Immune-response to Carbo n Fiber Reinforced Epoxy Composite Implants". Biomaterials,Vol. 12, pp , ISSN: G. Peluso, L. Ambrosio, M. Cinquegrani, L. Nicolais, G. Tajana, "Macrophage Activation Induced by Different Carbon/Epoxy Resin Composites". Journal of Biomedical Materials Research, Vol.25, pp , ISSN: X. Bian, L. Ambrosio, J. Kenny, L. Nicolais, E. Occhiello, M. Morra, F. Garbassi, A.T. Di Benedetto, "The Effects of Surface Treatment of Fibers on Composite Interfacial Properties. I: Single Carbon Fiber/Epoxy Resin Composite System". Journal of Adhesion Science and Technology, Vol.5, No.5, pp , M.C. Tanzi, L. Ambrosio, S. Iannace, L. Nicolais, B. Mambrito, "Comparative Physical Tests on Segmented Polyurethanes for Cardiovascular Applications". Clinical Materials, Vol.8, No.1, 57-64, ISSN: G. Peluso, M. Ranieri, L. Ambrosio, M. Cinquegrani, L. Nicolais, G. Tajana, "Biocompatibility of Two Different Cured Polyepoxy Composites". Clinical Materials, Vol.8, , ISSN: X. Bian, L. Ambrosio, J. Kenny, L. Nicolais, A.T. Di Benedetto, "Effect of Water Absorption on the Interfacial Properties of Nylon/Glass Fiber Composites". Polymer Composites, Vol. 12, N. 5, 1991, X. Bian, J. Kenny, L. Ambrosio, L. Nicolais, "Development and Application of the Single Fiber Technique (SFT) for the Evaluation and Analysis of Fiber/Matrix Adhesion in Polymeric Composites". Chimica Oggi/Chemistry Today, June 1991, S. Iannace, L. Ambrosio, L. Nicolais, A. Rastrelli, A. Pastorello, "Thermomechanical Properties of Hyaluronic Acid Derived Products". Journal of Materials Science: Materials in Medicine, 3, 1, 1992, ISSN: P.A. Davis, S.J. Huang, L. Ambrosio, L. Nicolais, D. Ronca, "A Biodegradable Composite Artificial Tendon". Journal of Materials Science: Materials in Medicine, 3, 5, September 1992, ISSN: M.C. Tanzi, M. Resnati, M.G. Lampugnani, R. Anouchinsky, L. Ambrosio, B. Mambrito, E. Dejana, "Comparative Biological Tests on Segmented Polyurethanes for Cardiovascular Applications", Clinical Materials, 12, 1993, ISSN:

10 13. P.A. Netti, J.C. Shelton, P.A. Revell, C. Pirie, S. Smith, L. Ambrosio, L. Nicolais and W. Bonfield, " Hydrogels as an Interface Between Bone and an Implant". Biomaterials, Vol. 14, No. 14, ISSN: L. Ambrosio, A. Apicella, M. Mensitieri, L. Nicolais, S.J. Huang, M. Marcacci, G. Peluso, "Physical and Chemical Decay of Prosthetic ACL after "in vivo" Implantation", Clinical Materials, 15, (1994), ISSN: O. Petillo, G. Peluso, L. Ambrosio, L. Nicolais, W.J.Kao, J.M. Anderson, "In Vivo Induction of Macrophage Ia Antigen (MHC class II) Expression by Medical Polymers in the Cage Implant System", Journal of Biomedical Materials Research, Vol.28, , ISSN: M. Mensitieri, L. Ambrosio, L. Nicolais, L. Balzano, D. Lepore, "The Rheological Behaviour of Animal Vitreus and its Comparison with Vitreal Substitutes", Journal of Materials Science: Materials in Medicine, vol.5, 1994, ISSN: G. Peluso, O. Petillo, L. Ambrosio, L. Nicolais, "Polyetherimide as Biomaterial: Preliminary in vitro and in vivo Biocompatibility Testing", Journal of Materials Science: Materials in Medicine, vol.5, 1994, ISSN: S. Iannace, L. Ambrosio, S.J. Huang, L. Nicolais, "Poly(3-Hydroxybutyrate)-co-(-3- Hydroxyvalerate)/Poly-l-Lactide Blends: Thermal and Mechanical Properties", Journal of Applied Polymer Science, Vol.54, 1994, pp ISSN: G. Peluso, O. Petillo, M. Ranieri, M. Santin, L. Ambrosio, D. Calabrò, B. Avallone, G. Balsamo, "Chitosan-mediated stimulation of macrophage function", Biomaterials, 1994, Vol.15, N.15. ISSN: M. Mensitieri, L. Ambrosio, S. Iannace, A. Perbellini, L. Nicolais, "Viscoelastic Evaluation of Different Knee Osteoarthritis Therapies", Journal of Materials Science: Materials in Medicine, Vol.6, N.3, , ISSN: S. Iannace, L. Ambrosio, S.J. Huang, L. Nicolais, "Effect of Degradation on the Mechanical Properties of Multiphase Polymer Blends: PHBV/PLLA", Journal of Macromolecular Science-Pure and Applied Chemistry, A32(4), pp (1995). ISSN: S. Iannace, G. Sabatini, L. Ambrosio, L. Nicolais, "Mechanical behaviour of composite artificial tendons and ligaments", Biomaterials, 1995, Vol.16, N.9. ISSN: L. Ambrosio, P.A. Netti, S. Iannace, S.J. Huang, L. Nicolais, Composite hydrogels for intervertebral disc prostheses. Journal of Materials Science: Materials in Medicine, 7, , ISSN: S. Iannace, L. Ambrosio, A. D Amore, L. Nicolais, Non-linear viscoelasticity of Hydrothane. Journal of Materials Science: Materials in Medicine, 7, , ISSN: M. Santin, S. J. Huang, S. Iannace, L. Ambrosio, L. Nicolais, G. Peluso, "Synthesis and Characterization of a new interpenetrated poly-(2-hydroxyethylmethacrylate) - gelatin composite polymer. Biomaterials, 17, , ISSN: P.A. Netti, A. D'Amore, D. Ronca, L. Ambrosio, L. Nicolais, "Structure-Mechanical Properties Relationship of Natural Tendons and Ligaments", Journal of Materials Science: Materials in Medicine, 7, , ISSN:

11 27. P. A. Netti, M.A. Del Nobile, G. Mensitieri, L. Ambrosio, L. Nicolais, Water transport in hyaluronic acid esters. Journal of Bioactive and Biocompatible Polymers, vol.11, October 1996, ISSN: M. Mensitieri, L. Ambrosio, L. Nicolais, D. Bellini, M. O Regan, Viscoelastic properties modulation of a novel autocrosslinked hyaluronic acid polymer. Journal of Materials Science: Materials in Medicine, 7, , ISSN: L. Ambrosio, G. Carotenuto, G. Marletta, L. Nicolais, A. Scandurra Wear effects in retrieved acetabular UHMW-PE cups. Journal of Materials Science: Materials in Medicine, 7, , ISSN: G. Peluso, O. Petillo, J.M. Anderson, L. Ambrosio, L. Nicolais, M.A.B. Melone, F.O. Eschenbach, S.J. Huang, The Differential effects of poly-(2-hydroxyethylmethacrylate) and poly-(2-hydroxyethylmethacrylate)/ poly(e-caprolactone) polymers on cell proliferation and collagen synthesis by human lung fibroblasts. Journal of Biomedical Materials Research, Vol. 34, , ISSN: R. De Santis, S. Iannace, P.A. Netti, L. Ambrosio, Composite structures for tendon and ligament prostheses, Anales de Quimica Int. Ed., 93:S64-S69, ISSN G. Carotenuto, M. Di Palo, G. Marino, L. Ambrosio, L. Nicolais, Comparison between in vitro and in vivo UHMW-PE degradation, Journal of Biomaterials Science: Polymer Edition VoL. 8, No. 6, pp , ISSN: A. Borzacchiello, L. Ambrosio, L. Nicolais, E.J. Harper, K.E. Tanner, W. Bonfield, Isothermal and non-isothermal polymerization of a new bone cement, Journal of Materials Science: Materials in Medicine, 9, , ISSN: L. Ambrosio, R. De Santis, L. Nicolais, Composite hydrogels for implants, ProcInstn Mech Engrs, Vol. 212, Part H, 93-99, ISSN: A. Borzacchiello, L. Ambrosio, L. Nicolais, E.J. Harper, K.E. Tanner, W. Bonfield, Comparison between the polymerization behavior of a new bone cement and a commercial one: modeling and in vitro analysis, Journal of Materials Science: Materials in Medicine, 9, 1998, ISSN: L. Ambrosio, S. Iannace, P. A. Netti, R. De Santis, L. Nicolais, Viscoelastic behavior of composite ligament prostheses, Journal of Biomedical Materials Research, Vol. 42, 6-12, ISSN: F. Branda, A. Costantini, G. Laudisio, A. Buri, L. Ambrosio, Hydroxyapatite coating of poly(2-hydroxyethylmetacrylate) hydrogel by biomimetic method, Journal of Material Science, 34, , ISSN: A. Merolli, V. Perrone, P. Tranquilli Leali, L. Ambrosio, R. De Santis, L. Nicolais, G. Gabbi, Response to polyetherimide based composite materials implanted in muscle and in bone, Journal of Material Science: Materials in Medicine, 10, , ISSN: L. Ambrosio, A. Borzacchiello, P.A. Netti, L. Nicolais, Rheological study on hyaluronic acid and its derivative solutions, Journal of Macromolecular Science-Pure and Applied Chemistry, A36,(7&8), , ISSN:

12 40. C. Carotenuto, G. Spagnuolo, L. Ambrosio, L. Nicolais, Macroporous hydroxyapatite as alloplastic material for dental applications, Journal of Material Science: Materials in Medicine, 10, , ISSN: O. Petillo, S. Margarucci, G. Peluso, A. Barbarisi, M.A.B. Melone, L. Ambrosio, L. Nicolais, Modulation of in vitro myogenesis induced by different polymer sustrates, Journal of Material Science: Materials in Medicine, 10, , ISSN: M. Bosetti, S. Mazzarelli, L. Nicolais, L. Ambrosio, M. Cannas, In vitro comparative comparative biocompatibility testing of carbofilm coated and uncoated polyetherimide for cardiovascular applications, Cells and Materials Vol.9, No.2, 1999, pp ISSN: A. Borzacchiello, L. Ambrosio, L. Nicolais, S.J. Huang, Synthesis and characterisation of satured and unsatured poly(alkene tartatre) and further cross-linking, Journal of Bioactive and Compatible Polymers, Vol. 15, 60-71, January ISSN: R. De Santis, D. Prisco, A.Apicella, L. Ambrosio, S. Rengo, L. Nicolais, Carbon fiber post adhesion to resin luting cement in the restoration of endodontically treated teeth, Journal of Material Science: Materials in Medicine, 11, 2000, ISSN: A. Borzacchiello, L. Ambrosio, C.V. Nicholas, M.D. Purbrick, Thermal and mechanical properties of oxymethylene linked polymers, Polymer International, 49: ISSN: R. De Santis, L. Ambrosio, L. Nicolais, Polymer based composite hip prostheses, Journal of Inorganic Chemistry, Vol. 79/1-4, , ISSN R. Barbucci, R. Ruoppoli, A. Borzacchiello, L. Ambrosio Synthesis, chemical and rheological characterisation of new hyaluronic based hydrogels, Journal of Biomaterials Science Polymer Edition, Vol.11, No.4, pp (2000). ISSN: R. De Santis, P. Anderson, K.E. Tanner, L. Ambrosio, L. Nicolais, W. Bonfield, G.R. Davis, "Bone fracture analysis on the short rod chevron-notch specimens using the X-ray computer micro-tomography", Journal of Material Science: Materials in Medicine, , 2000, ISSN: T. Avitabile, F. Marano, F. Castiglione, C. Bucolo, M. Cro, L. Ambrosio, C. Ferruto, A. Reibaldi, "Biocompatibility and biodegradation of intravitreal hyaluronan implants in rabbits", Biomaterials 22, 2001, A. Borzacchiello, L. Ambrosio, "Temporary network formation of low molecular weight hyaluronic acid derivatives", Journal of Biomaterials Science Polymer Edition, Vol. 12, N. 3, pp , R. De Santis, D. Prisco, S.N. Nazhat, F. Riccitiello, L. Ambrosio, S. Rengo, L. Nicolais, "Mechanical strength of tooth fragment reattachment", Journal of Biomedical Materials Research, 55, , G. Catapano, L. De Bartolo, V. Vico, L. Ambrosio, "Morphology and metabolism of hepatocytes cultured in Petri dishes, on films and in non-woven fabrics of hyaluronic acid esters", Biomaterials, 22, F. Branda, A. Costantini, G. Luciani, L. Ambrosio, "Improvement of swelling properties of PHEMA hydrogel by means of the biomimetic method", Journal of Biomedical Materials 12

13 Research, 57, A. Borzacchiello, L. Ambrosio, P.A. Netti, L. Nicolais, C. Peniche, A. Gallardo, J. San Roman, Chitosan-based hydrogels: Synthesis and characterisation, Journal of Material Science: Materials in Medicine, , ISSN: R. Barbucci, S. Lamponi, A. Borzacchiello, L. Ambrosio, M. Fini, P. Torricelli, R. Giardino, Hyaluronic Acid hydrogel in the treatment of osteoathritis. Biomaterials 23, 2002, A. Costantini, G. Luciani, F. Branda, L. Ambrosio, G. Mattogno, L. Pandolfi, Hydroxyapatite coating of titanium by biomimetic method. Journal of Material Science: Materials in Medicine, , ISSN: F. Causa, L. Manto, A. Borzacchiello, R. De Santis, P.A. Netti, L. Ambrosio, L. Nicolais, Spatial and structural dependence of mechanical properties of porcine intervertebral disc. Journal of Material Science: Materials in Medicine, , ISSN: M.P. Cataletto, S. Kaciulis, G. Mattogno, A. Mezzi, L. Ambrosio, F. Branda, XPS characterization of biocompatible hydroxyapatite-polymer coatings, Surface and Interface Analysis, 2002, 34, Hertegard S, Dahlqvist A, Laurent C, Borzacchiello A, Ambrosio L., Viscoelastic properties of rabbit vocal folds after augmentation Otolaryngol Head Neck Surg, 2003 Mar;128(3): Santin M., Wassall M.A., Ambrosio L., Nicolais L., Petillo O., Peluso G., Denyer S.P., Hydrothane interactions with biological components: a comparision with Chronoflex Journal of Applied Biomaterials & Biomechanics, 2003;1: ISSN: D. Prisco, R. De Santis, F. Mollica, L. Ambrosio, S. Rengo, L. Nicolais, Fiber Post Adhesion to Resin Luting Cements in the Restoration of Endodontically-Treated Teeth, Operative Dentistry, 2003, 28-5, R. De Santis, F. Mollica, L. Ambrosio, L. Nicolais, D. Ronca, Dynamic mechanical behavior of PMMA based bone cements in wet environment. Journal of Material Science: Materials in Medicine, , ISSN: G. Ciapetti, L. Ambrosio, L. Savarino, D. Granchi, E. Cenni, N. Baldini, S. Pagani, S. Guizzardi, F. Causa, A. Giunti, Osteoblast growth and function in porous poly(ecaprolactone) matrices for bone repair: a preliminary study, Biomaterials, 24 (2003), ISSN: Giavaresi G., Giardino R., Ambrosio L., Battiston G.A., Gerbasi R., Fini M., Rimondini L., Torricelli P., In vitro biocompatibility of titanium oxide for prosthetic devices nanostructured by metal-organic chemical vapour deposition. International Journal of Artificial Organs. Vol.28. N.8, pp ISSN A. Sannino, A. Esposito, A. De Rosa, A. Cozzolino, L. Ambrosio, L. Nicolais, Biomedical applications of a superabsorbent hydrogels for body water elimination in the treatment of edemas, Journal of Biomedical Materials Research, 67A: , ISSN V. Sanguinario, L. Ambrosio, M.P. Ginebra, J.A. Planell, Injectable composite hydrogels for orthopaedic application. Mechanical and Morphological Analysis, Key Engimeering 13

14 Materials, Vols (2004), pp Xuejun X., Netti P.A., Ambrosio L., Nicolais L., Sannino A, Preparation and characterisation of a Hydrogel from low-molecular weight hyaluronic acid. J. of Bioactive and Compatible Polymers, 2004, January, ISSN: Sannino A., Madaghiele M., Conversano F., Mele G., Maffezzoli A., Netti P.A., Ambrosio L., Nicolais L., Cellulose derivative-hyaluronic acid-based microporous hydrogels crosslinked through Divinyl Sulfone (DVS) to modulate equilibrium sorption capacity and network stability. Biomacromolecules, 2004, 5, ISSN: /bm De Santis R., Sarracino F., Mollica F., Netti P.A., Ambrosio L., Nicolais L., Continuous fibre reinfoced polymers as connective tissue replacement. Composite Science and Technology, 2004, 64, ISSN: M. Navarro, M.P. Ginepra, J.A. Planell, S. Zeppetelli, L. Ambrosio, Development and cell response of a new biodegradadble composite scaffold for guided bone regeneration. Journal of Material Science: Materials in Medicine, , ISSN: Leone G., Barbucci R., Borzacchiello A., Ambrosio L., Netti P.A., Migliaresi C., Preparation and physico-chemical characterisation of microporous polysaccharide hydrogels. Journal of Material Science: Materials in Medicine, , ISSN: Mollica F., De Santis R., Ambrosio L., Nicolais L., Prisco D., Rengo S., Mechanical and leakage behaviour of dentine-adhesive interface. Journal of Material Science: Materials in Medicine, , ISSN: Ambrosio L., Battista S., C. Borselli, Borzacchiello A., Causa F., De Santis R., Netti P.A., Zeppetelli, Biomimetic structure for implants and tissue engineering. The Medical Journal of Malaysia, 2004, 59, Suppl. B, ISSN Navarro M., del Valle S., Martinez S., Zeppetelli S., Ambrosio L., Planell J.A., Ginebra, M.P., New macroporous calcium phosphate glass ceramic for guided bone regeneration. Biomaterials, 25 (2004), ISSN: Giavaresi G., Ambrosio L., Battiston G.A., Casellato U., Gerbasi R., Fini M., Aldini N.N., Martini L., Rimondini L., Giardino R., Histomorphometric, ultrastructural and microhardness of a nanostructured titanium oxide coating by metal-organic chemical vapour deposition: an in vivo study. Biomaterials, 25 (2004), ISSN: Borzacchiello A., Mayol A., Garskog O., Dahlqvist A., L. Ambrosio, Rheological characterizarion of vocal folds after injection augmentation in a preliminary animal study. Journal of Bioactive and Compatible Polymers, Vol.19, , ISSN: De Santis R., Causa F., Sarracino F., Natti P.A., L. Ambrosio, Biomimetic composite hydrogels for tissue reconstruction, Annals of Transplantation, Vol9, N. 1A (Suppl.), 2004, pp.6-9. ISSN Xuejun X., Borzacchiello A., Netti P.A., Ambrosio L., Nicolais L., Hyaluronic-acid-based semi-interpenetrating materials, Journal of Biomaterials Science. Polymers Edition. Vol.15, No.9, pp , Giavaresi G., Branda F., Causa F., G. Luciani, Aldini N.N., Rimondini L., Ambrosio L., Giardino R, Poly(2hydroxyethyl methacrylate) biomimetic coating to improve 14

15 osseointegration of a PMMA/HA/Glass composite implant: In vivo mechanical and histomorphometric assessments International Journal of Artificial Organs. Vol.27. N.8, pp ISSN F. Rosso, M. Barbarisi, A. Barbarisi, A. Giordano, L. Ambrosio. Synthesis and characterisation of poly(2-hydroxyethyl methacrylate) polyelectrolyte complexes. Journal of Materials Science: Materials in Medicine June 15(6): M. Catauro, M.G. Raucci, F. De Gaetano, A. Buri, A. Marotta, L. Ambrosio, Sol-gel synthesis, structure and bioactivity of poly(caprolactone)/cao.sio2 hybrid material. Journal of Material Science: Materials in Medicine, , ISSN: Santin M., Motta A., Borzacchiello A., Nicolais L., Ambrosio L., Effect of PMMA cement radical polymerisation on the inflammatory response. Journal of Material Science: Materials in Medicine, , ISSN: De Santis R., Mollica F., Prisco D., Rengo S, Ambrosio L., Nicolais L., A 3D analysis of mechanically stressed dentin-adhesive-composite interfaces using X-ray micro-ct, Biomaterials, 26 (2005), ISSN: M.O.H. Cioffi, H.J.C. Voorwald, L.R.O. Hein, L. Ambrosio Effect of cold plasma treatment on mechanical properties of PET/PMMA composites, Composites Part A, applied science and manufacturing, 36 (2005) /j. 85. F. De Gaetano, L. Ambrosio, M.G. Raucci, A. Marotta, M. Catauro, Sol-gel processing of drug delivery materials and release kinetics, Journal of Material Science: Materials in Medicine, , ISSN: Borzacchiello A., Mayol L., Garskog O., Dahlqvist A., L. Ambrosio, Evaluation of characterizarion of injection augmentation treatment of hyaluronic acid based materials on rabbit vocal folds viscoelasticity. Journal of Material Science: Materials in Medicine, , ISSN: Esposito A., Sannino A., Cozzolino A., Nappo Quintiliano S., Lamberti M., Ambrosio L., Nicolais L., Response of intestinal cells and macrophages to an o rally administered cellulose-peg based polymer as a potential treatment for intractable edemas. Biomaterials, 26, (2005) Battista S., D. Guarnieri, C. Borselli, S. Zeppetelli, A. Borzacchiello, L. Mayol, D. Gerbasio, D.R. Keene, L. Ambrosio, P.A. Netti, The effect of matrix composition of 3D constructs on embryonic stem cell differentiatio n. Biomaterials, 26, (2005) Sannino A., Pappadà S. Madaghiele M., Maffezzoli A., Ambrosio L., Nicolais L., Crosslinking of cellulose derivatives and hyaluronic acid with water-soluble carbodiimide. Polymer, 46, 2005, Ambrosio L., Materials Concern, Medical Device Development, 2005, Vol.2, R. De Santis, F. Mollica, R. Esposito, L. Ambrosio, L. Nicolais, An experimental and theoretical composite model of the human mandible Journal of Material Science: Materials in Medicine, , ISSN: L. Ambrosio, P.A. Netti, Editorial of Journal of Material Science: Materials in Medicine, , ISSN:

16 93. C. Giordano, V. Sanginario, L. Ambrosio, L. Di Silvio, M. Santin, Chemical-Physical Characterization and in vitro Preliminary Biological Assessment of Hyaluronic Acid Benzyl Ester-Hydroxyapatite. Composite. J Biomater Appl : F. Mollica, M. Ventre, F. Sarracino, L. Ambrosio, L. Nicolais, Mechanical properties and modelling of a hydrophilic composite used as a biomaterial. Composites Science and Technology 66 (2006) F. Causa, P. A. Netti, L. Ambrosio, G. Ciapetti, N. Baldini, S. Pagani, D. Martini, A. Giunti, Poly-e-caprolactone/hydroxyapatite composites for bone regeneration: in vitro characterization and human osteoblast response. Journal of Biomedical Materials Research, 76A, Issue 1, January 2006, ISSN V. Sanginario, M.P. Ginebra, K.E. Tanner, J.A. Planell, L. Ambrosio, "Biodegradable and semi-biodegradable composite hydrogels as bone substitutes: morphology and mechanical characterization". Journal of Materials Science: Materials in Medicine, 2006, 17: F. Causa, F. Sarracino, R. De Santis, P. A. Netti, L. Ambrosio, L. Nicolais, Basic structural parameters for the design of composite structures as ligament augmentation devices. Journal of Applied Biomaterials & Biomechanics, 2006; Vol.4, no.1, A. Maltese, A. Borzacchiello, L. Mayol, C. Bucolo, L. Nicolais, L. Ambrosio, Novel polysaccharides-based viscoelastic formulations for ophthalmic surgery: Rheological characterization, Biomaterials 27 (2006), G. Ciapetti, L. Ambrosio, G. Marletta, N. Baldini, A. Giunti, Human bone marrow stromal cells: In vitro expansion and differentiation for bone engineering. Biomaterials 27 (2006) A. Esposito, A. Mezzogiorno, A. Sannino, A. De Rosa, D. Menditti, V. Esposito, L. Ambrosio, Hyaluronic acid based materials for intestine tissue engineering: A morphological and biochemical study of cell-material interaction. Journal of Materials Science: Materials in Medicine, (2006) 17: Morris C., Thorpe J., Ambrosio L., Santin M. The soybean isoflavone genistein induces differentiation of MG63 human osteosarcoma osteoblasts J. Nutr. 136, 1-5 (2006) 102. Roberto De Santis, Veronica Ambrogi, Cosimo Carfagna, Luigi Ambrosio, Luigi Nicolais. Effect of microencapsulated phase change materials on the thermo-mechanical properties of poly(methyl-methacrylate) based biomaterials. Journal of Materials Science: Materials in Medicine, (2006) 17: C. Chiari, U. Koller, R. Dorotka, C. Eder, R. Plasenzotti, S. Lang, L. Ambrosio, E. Tognana, E. Kon, D. Salter, S. Nehrer. A tissue engineering approach to meniscus regeneration in a ship model. Osteoarthrisis and Cartilage, 2006, 14, C. Luponio, F. Causa, E. Angelini, M.R. Pinasco, L. Ambrosio, Effect of micrometerscale metallic fillers on the mechanical and corrosion resistamce properties of alternative materials for conservative dentistry. Journal of Applied Biomaterials & Biomechanics, 2006; Vol.4, no.3,

17 105. R De Santis, F. Mollica, F. Zarone, L. Ambrosio, L. Nicolais, Biomechanical effects of titanium implants with full arch bridge rehabilitation on a synthetic model of the human jaw. Acta Biomaterialia, 3, 2007, Borselli, C., Oliviero, O., Battista, S., Ambrosio, L., and Netti, P.A. (2007) Induction of directional sprouting angiogenesis by matrix gradients. J Biomed Mater Res Part A. 80A(2): P.A. Revell, E. Damien, L. Di Silvio, N. Gurav, C. Longinotti, L. Ambrosio, (2007), Tissue engineered intervertebral disc repair in pig using injectable polymers. Journal of Materials Science: Materials in Medicine, (2007) 18: R De Santis, M. Catauro, L. Di Silvio, L. Manto, M.G. Raucci, L. Ambrosio, L. Nicolais, (2007) Effect of polymer amount and processing conditions on the in vitro behaviour of hybrid titanioum dioxide/polycaprolactone composites. Biomaterials, 28 (2007), V. Guarino, F. Causa, L. Ambrosio, (2007) Bioactive scaffolds for bone and ligament tissue. Expert review of Medical Devices, May 2007, vol. 4, N0.3, C. Giordano, F. Causa, L. Di Silvio, L. Ambrosio (2007), Chemical-physical and preliminary biological properties of poly(2-hydroxyethyl methacrylate)/ poly(ecaprolactone)/hydroxyapatite composite. Journal of Materials Science: Materials in Medicine, (2007) 18: G. Carotenuto, A. Longo, L. De Petrocellis, S. De Nicola, P. Repetto, P. Perlo, L. Ambrosio (2007) Synthesis of molecular gold clusters with luinecsence properties by mercaptide thermolysis in polymer matrices. International Journal of Nanoscience, Vol.6, No. 1, 2007, G. Carotenuto, A. Longo, P. Repetto, P. Perlo, L. Ambrosio (2007), New polymer additives for photoelectric sensing : Sensors and Actuators B, 125, (2007), M. Catauro, M.G. Raucci, G. Ausanio, L. Ambrosio (2007), Solg-gel synthesis, charcterization and bioactivity of poly(ether-imide)/tio2 hybrid materials. Journal of Applied Biomaterials & Biomechanics, 2007; Vol.5, no.1, A. Borzacchiello, L. Mayol, P. A. Ramires, A. Pastorello,C. Di Bartolo, L. Ambrosio, E. Milella, Structural and rheological characterization of hyaluronic acid -based scaffolds for adipose tissue engineering. Biomaterials 28 (2007) G. Cardone, G. Carotenuto, A. Longo, P. Perlo, L. Ambrosio. Synthesis of gold nanoplates by mercaptide thermolysis in poly(vinyl acetate). express Polymer Letters, Vol.1, No.9 (2007) L. Savarino, N. Baldini, M. Greco, O. Capitani, S. Pinna, S. Valentini, B. Lombardo, M.T. Esposito, L. Pastore, L. Ambrosio, S. Battista, F. Causa, S. Zeppetelli,V. Guarino, P.A. Netti, The performance of poly-e-caprolactone scaffolds in a rabbit femur model with and without autologous stromal cells and BMP4. Biomaterials 28 (2007)

18 117. Filippo Causa, Paolo A. Netti, Luigi Ambrosio, A multi-functional scaffold for tissue regeneration: The need to engineer a tissue analogue. Biomaterials 28 (2007) R. Valletta, D. Prisco, R. De Santis, L. Ambrosio, R. Martina, Evaluation of the debonding strength of orthodontic brackets using three different bonding systems. European Journal of Orthodontics 29 (2007)

19 Book Chapters A.T. Di Benedetto, L. Nicolais, L. Ambrosio, J. Groeger, "Stress Transfer and Fracture in Single Fiber/Epoxy Composites". Composite Interface, H. Hishida and J. Koenig Editors, Elselvier Science Publiscing Co. Inc, pp , ISBN: L. Ambrosio, G. Caprino, L. Nicolais, L. Nicodemo, S.J. Huang, G. Guida, D. Ronca, "Composite Materials for Bone Fractures Fixation". Composite Structure 4, I.H. Marshall Editor, Vol. 2, pp , ISBN: L. Nicolais, S. Iannace, L. Ambrosio, "Materiali Compositi per Protesi Articolari,in Chirurgia Maxillo-Facciale, (C. Giardino, Ed.), Monduzzi Editore, pp , L. Ambrosio, G. Peluso, "Progettazione, Caratterizzazione Chimico-Fisica e Biologica dei Biomateriali, in Chirurgia Maxillo-Facciale, (C. Giardino, Ed.), Monduzzi Editore, pp , P.A. Davis, S.J. Huang, L. Ambrosio, L. Nicolais, "Modified PHEMA Hydrogels", in High Performance Biomaterials: A Comprensive Guide to Medical/Pharmaceutical Applications, (M. Szycher Ed.) Technomic Publishing Co. Inc., Lancaster, PA, USA, pp , ISBN: L. Ambrosio, P. A.Netti, L. Nicolais, I nuovi materiali per applicazioni biomediche in Il Corpo Umano tra Natura e Progetto, (G.M. Pace Ed.) Futuro Remot, CUEN, Napoli, 1993, pp L. Ambrosio, S. Iannace, M. Mensitieri, P.A. Netti, L. Nicolais, "Structural Materials for Biomedical Applications", in Moving Forward with 50 Years of Leadership in Advanced Materials, (K. Drake, J. Bauer, T. Serafini, P. Cheng, Eds.) SAMPE, Vol. 39, Book 1, 1994: ISBN: L. Ambrosio, G. Guida, L. Nicolais, D. Ronca, "Polimeri e compositi", in Biomeccanica Ortopedica e Traumatologica, (F. Pipino, L. Quagliarella Eds.), UTET 1995, Ch. 20, pp L. Ambrosio, G. Peluso, P.A. Davis, Biomaterials and Their Biocompatibilities, in Human Biomaterials Applications, (D.L. Wise, D.J. Tarantolo, D.E. Altobelli, M.J. Yaszemski, J.D. Gresser, Eds.), Humana Press Inc., Totowa, NJ, USA, 1, 3-17, ISBN: L. Ambrosio, S. Iannace, L. Nicolais, Composite Materials for Biomedical Applications: Tendon and Ligament Prostheses, in The of Science for the Improvement of Human Life, (R. Barbucci Ed.), Ed. Cadmio, Arti Grafiche Ticci, 1996, pp L. Ambrosio, G. Carotenuto, L. Nicolais, Composite Materials, in Handbook of Biomaterials Properties, (J. Black, G. Hastings eds.), Chapman & Hall, London, 1998, ISBN S. Iannace, L. Ambrosio, L. Nicolais, Effect of crystallization temperature on the structure of amorphous domain of poly-l-lactide, in Frontiers in Biomedical Polymer Applications, (R.M. Ottenbrite, ed.), Technomic Pubbl.Co. Inc., Lancaster PA, 1998, ISBN: L. Ambrosio, R. De Santis, L. Nicolais, Composite hydrogels as intervertebral disc prostheses in Science and Technology of Polymers and Advanced Materials (P.N. Prasad et

20 al. eds.), Plenum Press, New York, 1998, pp P. Vena, R. Contro, R. Pietrabissa, L. Ambrosio, Design of materials subject to biomechanical compatib ility constraints in Solid Mechanics and its Applications, Synthesis in BioSolid Mechanics (P. Pedersen and M.P. Bendsoe, eds.), Kluwer Academic Publisher, Dordrecht, The Netherland, pp , A. Borzacchiello, P.A. Netti, L. Ambrosio, "Hyaluronic acid derivatives mimic the rheological properties of vitreous body", in New Frontiers in Medical Sciences: Redefining Hyaluronan (G. Abatangelo and P.H. Weigel, eds.), Elsevier Science B.V., 2000, pp ISBN: P.A. Netti, L. Ambrosio, L. Nicolais, Thermodynamics of water sorption in hyaluronic acid snd its derivative in Polymers for medical Applications in the Twenty First Century, (R.M. Ottenbrite and S.W. Kim, Eds), Chapter 12, , Tehnomics Publishing Co., Lancaster, PA, USA, L. Ambrosio, R. De Santis, L. Nicolais, Composite materials in medicine in Composite Materials (D. Baptiste and F. Rustichelli eds.), Editura Sudura, Timisora, Romania 2000, pp ISBN L. Ambrosio, P. Netti, B. Santaniello, L. Nicolais, "Composite materials as scaffolds for tissue engineering", in Biomedical Polymers and Polymer Therapeutics, (E. Chiellini, J. Sunamoto, C. Migliaresi, R.M. Ottenbrite, D. Cohn eds.), Kluwer Academic/Publisher, 2001, ISBN L. Ambrosio, Le innovazioni dei materiali nei processi produttivi, in La Gestione dell Innovazione di Prodotto: Il Caso delle Calzature e degli Imballaggi Flessibili. (P.Stampacchia & L. Nicolais, eds.), Edizioni Scientifiche Italiane, pp , ISBN A. Borzacchiello, L. Ambrosio, P. A. Netti, L. Nicolais, Biomimetic Materials, in Polymers in Europe, Quo Vadis?, European Polymer Federation, AIM Magazine, Special Issue July 2001, pp L. Ambrosio, P. A. Netti, P. A. Revell, "Tissues" in Integrated Biomaterials Science, (R. Barbucci, Ed.), Kluver Academic/Plenum Publishing Co, 2002 New York, ISBN L. Ambrosio, P. A. Netti, L. Nicolais "Soft Tissue", in Integrated Biomaterials Science, (R. Barbucci, Ed.), Kluver Academic/Plenum Publishing Co, 2002 New York, ISBN D. Lepore, L. Ambrosio, R. De Santis, L. Nicolais, L. Scullica, "The Eye", in Integrated Biomaterials Science, Kluver Academic/Plenum Publishing Co, 2002 New York, ISBN P. A. Netti, L. Ambrosio, "Articular cartilage", in Integrated Biomaterials Science, (R. Barbucci, Ed.), Kluver Academic/Plenum Publishing Co, 2002 New York, ISBN M. Santin, L. Ambrosio, A. W. Lloyd, S. P. Denyer "Soft Tissue Replacement", in Integrated Biomaterials Science, (R. Barbucci, Ed.), Kluver Academic/Plenum Publishing Co, 2002 New York, ISBN