Dottoressa Monica Antinori

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1 Dottoressa Monica Antinori Ginecologa Direttrice sanitaria Clinica Raprui La dottoressa Monica Antinori ha studiato Medicina e Chirurgia all Università La Sapienza di Roma dove, nel 2011,si è laureata con lode presentando la tesi sperimentale L uso del Sildenafil come ausilio per migliorare le condizioni d impianto embrionale e successivamente, nel 2006, ha conseguito la specializzazione in Ostetricia e Ginecologia con tesi sulla Vetrificazione di ovociti umani con metodica C r y o t o p : e l e v a t a s o p r a v v i v e n z a a l l o scongelamento e buone condizioni alla nascita. Iscritta all Albo dei Medici-Chirurghi della Provincia di Roma, dal 2001 al 2006 ha partecipato all attività clinica e didattica dell Unità di Chirurgia Mininvasiva diretta dal Prof Carlo De Angelis presso l istituto di Ginecologia ed Ostetricia dell Università La Sapienza di Roma.Dal 2004 al 2005ha svoltoun tirocinio in Ostetricia e Ginecologia presso la Clinica Santa Famiglia Roma, partecipando all attività didattica e formativa della struttura. La Dottoressa Antinori, dopo aver ricoperto il ruolo di coordinatore dell attività scientifica e membro dello staff medico, è dal 2012, oltre che direttrice della Clinica,Responsabile della PMA del Centro Raprui. È autrice di oltre 20 pubblicazioni all interno di riviste scientifiche specializzate in medicina della riproduzione umana e ha partecipato in qualità di relatore a numerosi congressi nazionali e internazionali di prestigio in ambito medico-scientifico. Inoltre, è membro dell Editorial Board dell autorevole rivista scientifica ReproductiveBioMedicine Online (RBM Online). Attività scientifica e di perfezionamento Tra le varie specializzazioni pre e post laurea si annoverano: 2001 Corso Medicina d Urgenza BSLD PROVIDER 2003 Perfezionamento I Concepimenti Assistiti presso il Centro SISMER Bologna 2004 Corso residenziale La diagnosi genetica preimpianto (PGD) Tirocinio presso Unità Funzionale di Ostetricia e Ginecologia della Casa Di Cura Santa Famiglia Servizio di Chirurgia Mininvasiva diretto dal Prof. Carlo De Angelispresso il Policlinico Umberto I di Roma, Dipartimento di Scienze OstetricheGinecologiche e Puericultura

2 La dottoressa Antinori ha effettuato anche diversi tirocini e corsi di perfezionamento all estero, in particolare: Stati Uniti, 2004 Training Stage in Medically Assisted Reproductive Techniques and in Management of Endometriosis con la presentazione di un seminario sulle metodiche ecografiche, presso OakBrookFertility Center, a Chicago. Russia,2004Corso di aggiornamento in The Latest Advances In Assisted Reproductive Technologies presso AltraVita IVF - Center for Human Reproduction, a Mosca. Germania, 2006 Corso In vitromaturationofhuman oocytes pressoil Women Hospital of the Schleswig-Holstein University Campus Lubeck, Klinikf Fur Frauenheilkunde und Geburtshilfe, a Lubecca. Inghilterra, 2008Advanced ultrasound in gynecology and reproductive medicine diploma course nell ambito del The second World Congress on mild approaches in Assisted Reproduction, a Londra. Pubblicazioni e relazioni a cura di Monica Antinori L expertise di Monica è raccolto in più di 40 contributi scientifici, tra studi internazionali, pubblicazioni, e relazioni presentate in Italia e all estero, frutto di lunghi anni di studio e di ricerca clinica. PUBBLICAZIONI Fertilization with human testicular spermatids: four successful pregnancies Human Reproduction vol. 12 n 2 pag Successful fertilization and pregnancy after injection of frozen-thawed round spermatids into human oocytes Human Reproduction vol.12 n 3 pag A predictive method to achieve pregnancy in recipients undergoing an egg donation program Embryo transfer 24 h after assisted hatching improves implantation and pregnancy rate Human Reproduction, Vol. 13, June 1998,14th ESHRE Congress Goteborg Successful delivery after injection of frozen thawed roundf spermatids into human oocytes Human Reproduction, Vol. 13, June 1998,14th ESHRE Congress Goteborg Pregnancies after sperm injection into cryopreserved human oocytes Testicular sperm cell recovery: efficiency of fine needle testicular sperm aspiration (TESA) Psychological needs and stress evaluation of 20 couples undergoing IVF treatment Oocyte cryopreservation is a viable alternative option for patients who refuse embryo freezing

3 The use of round or elongated spermatids for ICSI, which is more effective? Laser assisted hatching: improvement of implantation and higher pregnancy rates Personal and marital adjustment Before and after an In Vitro Fertilization/Embryo transfer Treatment Obstetric and prenatal outcome in menopausal women a 12-year clinical study Reproductive BioMedicine Online Vol.6, n 2, Cryotop vitrification method on human oocytes results in high survival rate and healthy deliveries Reproductive BioMedicine Online Vol 14, n 1,January 2007 Vitrification of human oocytes: high survival rate and healthy deliveries Human Reproduction Volume 22, Supplement 1, July th ESHRE Congress Lyon Intracytoplasmic morphologically selected sperm injection (IMSI):a prospective randomized trial Reproductive BioMedicine OnlineVol 16, n 6,June 2008 Three Years of clinical application in human oocytes vitrification: high survival rates and healthy deliveries Human Reproduction Volume 23, Supplement 1, July 2008, 24th ESHRE Congress Barcellona A prospective randomized trial to verify potential advantages offered by IMSI procedure in daily IVF routine Human Reproduction Volume 23, Supplement 1, July 2008, 24th ESHRE Congress Barcellona Oocytes vitrification applied on women with impairment of their ovarian function Human Reproduction Volume 25,Supplement 1, July 2010, 24th ESHRE Congress Barcellona Antioxidants in IMSI In Parekattil, Sijo J., Agarwal, Ashok A Male Infertility: Contemporary Clinical Approaches, Andrology, ART & Antioxidants Springer 2012 "IMSI as a Valuable Tool for Sperm Selection During ART In: Carrell DT, RacowskyC, Schlege P Nl, Fauser B.C.J.M. Biennial Review of Infertility, Volume 2 New York Inc. Springer-Verlag; June 2011 "Intracytoplasmic Morphologically-selected Sperm Injection In: Gardner, Weissman,Howles,Shoham Textbook of assisted reproduction techniques, Volume 1 Informa Healthcare;June 2012 RELAZIONIPRESENTATE Embryo transfer in IVF: technical procedure II W.A.R.M. World Congress Gametes and alternatives:new challenges in reproductive technologies Rome, May Vitrification of human oocytes:preliminary results First World Congress on human oocytes cryopreservation Bologna,June Vitrification of human oocytes, Invited speaker and teacher

4 III W.A.R.M. World Congress. Course and workshop on: vitrification methods of cryopreservation of human oocytes and embryos Rome, September An alternative strategy for improving pregnancy in poor responders: cumulative seminatural cycles and oocytes vitrification Fifth World Congress on Ovulation Induction Rome, September Vitrification of human ovocyte, Invited speaker Corso teorico pratico sulla vetrificazione Sevilla (Spain), 15th September 2007 Human oocytes vitrification: high survival rate and healthydeliveries 14th World Congress on In Vitro Fertilization & 3rd World Congress on In Vitro Maturation Montreal, September years of clinical application in Human Oocyte Vitrification: high survival rate and healthy deliveries,invited speaker Second World Congress on human oocytes cryopreservation Bologna,November 30 - December years of clinical application in human oocyte vitrification: high survival rate and healthy deliveries 24th edition of the Annual Meeting of the European Society for Human Reproduction and Embryology- ESHRE- Barcellona, July IMSI experience in RAPRUI, Invited speaker IV W.A.R.M. World CongressBEYOND INFERTILITY: BREAKTHROUGHS IN REPRODUCTIVE MEDICINE AND TECHNOLOGY Guadalajara (Mexico),September Vitrification of human oocytes by Cryotop method, Invited speaker and teacher IV W.A.R.M. World CongressBEYOND INFERTILITY: BREAKTHROUGHS IN REPRODUCTIVE MEDICINE ANDTECHNOLOGY Guadalajara (Mexico), September Successful oocyte vitrification program, Invited speaker Work shop on: Oocyte cryopreservation:current knowledge and future perspectives Roma, September Gravidanze da ovociti congelati o vetrificati,implantation rate, Invited speaker Dall ovulazione alla gravidanza Università di Pavia, October Intracytoplasmic Morphologically Selected Sperm Injection (IMSI), Invited speaker 22nd Annual Course In Vitro Fertilization AndEmbryoTransfer A Conprehensive Update David Geffen School of Medicine at UCLA Santa Barbara (California), July Vitrification of the human oocyte,invited speaker 2nd International Congress on Fallopian Tubes: from the Ovary to the Endometrium London,September Nuclear vacuoles and DNA fragmentation Warm Symposium Rome, June 2010 Oocytes vitrification applied on women with impairment of their ovarian function

5 26th edition of the Annual Meeting of the European Society for Human Reproduction and Embryology- ESHRE- Rome, June 2010 Oocytes vitrification for milders IVF in Europe, Invited speaker 3rd World Congress on Mild Approaches in Assisted Reproduction Yokohama (Japan), July Clinical application of oocytes vitrification in Italy, Invited speaker First International Symposium of Vitrification Nuevo Vallarta (Mexico),March Understanding vitrification, Invited speaker and teacher GAMETES Symposium and Workshop Mumbai (India), September Understanding Fine Sperm Morphology- A Link to Improve Fertility, Invited speaker and teacher GAMETES Symposium and Workshop Mumbai (India), September rd Congress of Society of Reproductive Medicine October 5-9, 2011, Antalya / Turkey ACE Congress Leeds (UK), January Fifth International Congress of the Jordanian Society for Fertility and Genetics Amman - Jordan 25th-26th April 2013 La conservazione della fertilità oggi, Direzione Scientifica e relatrice: Conservazione della fertilità femminile Opzioni terapeutiche della Crioconservazione Seminario e Workshop pratico Primo corso italiano di vetrificazione di ovuli ed embrioni con metodo Cryotec Roma 1 Giugno 2013