CURRICULUM VITAE GRESPI SILVIA M.D. Born in Pisa on 27 March 1978 Nationality: Italian Address: Cascina-Pisa, via Piccina 7, 56021, Tuscany e-mail: silviagrespi@hotmail.it Telephone number +39 348 4078796 EDUCATION: Master s degree in Radiotherapy, thesis title: Role of high dose rate brachytherapy in tumors of the tracheobronchial tree. University of Pisa, 2005-2009; Master s degree in Medicine and Surgery, thesis title: Neoadjuvant radiochemiotherapy treatment in locally advanced rectal cancer: down-staging and prognosis. University of Pisa, December 2005; Second level university master s degree in Clinical Trials of Drugs, University of Pisa, December 2009; Second level university master s degree in Current events and innovations in breast cancer radiotherapy, University of Chieti, in collaboration with Washington University St.Louis (USA) and IEO of Milan, 2010-2011; Second level university master s degree in Oxygen-Ozone Therapy, University of Pavia, March 2019. WORK EXSPERIENCES: - Radiotherapist M.D. Manager to Radiotherapy of Casa di Cura San Rossore, Pisa, since July 2018 currently active. - Radiotherapist M.D. to Radiotherapy of Istituto di Ricerche Cliniche Ecomedica Empoli (Florence), from December 2013 to Novembar 2016. - Radiotherapist M.D. to Radiotherapy of Malzoni Radiosurgery Center Agropoli (SA), from May 2011 to December 2011.
SKILLS: During my work I used: 3D-RT IMRT VMAT IGRT SRS CBCT TBI Brachiterapy IORT (in mammary tumors) 4D CT Respiratory Gating Elekta Active Breathing Coordinator (ABC) Respiratory Gating Varian Real-time Position Management (RPM) Software: Eclipse, Monaco, MIM. LANGUAGES: English: Level B1 PUBBLICATIONS: Clinical outcome of tailored adjuvant postoperative chemoradiotherapy in IB FIGO stage cervical cancer. Fabrini MG, Gadducci A, Perrone F, Coscio S, La Liscia C, Pasqualetti F, Grespi S, Cionini L Anticancer Res. 2009 Oct. 29(10): 4205-4210 Perioperative High-dose-rate brachytherapy in the treatment of recurrent malignant gliomas. Fabrini MG, Perrone F, De Franco L, Pasqualetti F, Grespi S, Vannozzi R, Cionini L Strahlenther Onkol. 2009 Aug. 185(8): 524-529 Repeat stereotactic radiosurgery in the management of brain metastases from NSCLC: A case report and review of the literature. Marvaso G, Barone A, Vaccaro C, Bruzzaniti V, Grespi S, Scotti V, Bianco C Oncology letters. 2013 June 6: 897-900
POSTER/ ABSTRACT: Stereotactic body radiation therapy and target therapy for treatment of oligometastatic renal cell cancer. S.Grespi, C.Menichelli, A.Fanelli, P.Ferraza, G.Pastore, P.Frallicciardi, F.Casamassima. XXVI National Congress AIRO, XXX National Congress AIRB. Rimini, 30 Septembar,1-2 October 2016 (oral communication C058). Role of SABR in patients with centrally located NSCLC. C.Menichelli, A.Fanelli, P.Ferrazza, S.Grespi, G.Pastore, P.M.Frallicciardi, F.Casamassima. XXVI National Congress AIRO, XXX National Congress AIRB. Rimini, 30 Septembar,1-2 October 2016 (Poster P062). Stereotactic body radiotherapy for unresectable cholangiocarcinoma: a single institutional experience. P.Ferrazza, C.Menichelli, A.Fanelli, S.Grespi, G.Pastore, P.M.Frallicciardi, F.Casamassima. XXVI National Congress AIRO, XXX National Congress AIRB. Rimini, 30 Septembar,1-2 October 2016 (Poster P130). Modality of progression after stereotactic radiation therapy for oligometastatic prostate cancer nodal recurrence. S.Grespi, P.Ferrazza, A.Fanelli, C.Menichelli, G.Pastore, P.M.Frallicciardi, F.Casamassima. XXVI National Congress AIRO, XXX National Congress AIRB. Rimini, 30 Septembar,1-2 October 2016 (Poster P156). Analisi retrospettiva multicentrica di 678 lesioni metastatiche epatiche trattate con radioterapia stereotassica. C.Menichelli, V.Scotti, S.Grespi, A.Fanelli,G. De Pascalis, T.Petrone, G.Pastore, C.Arricchiello, L.Bottalico, P.Grosso, F.Bruno, F.Casamassima. XXV National Congress AIRO. Rimini, 7-10 November 2015 (Oral communication C031). La VMAT ipofrazionata come trattamento neoadiuvante nel NSCLC centrale. C.Menichelli, F.Casamassima, G.Coraggio, A.Grandinetti, I.Petrini, A.Fanelli, S.Grespi, M.Panichi, G.Pastore, C.Arricchiello,A.Tagliagambe, MG Fabrini. XXV National Congress AIRO. Rimini, 7-10 Novembar 2015 (Poster P108). Ripresa di malattia linfonodale limitata da cancro prostatico: ruolo della radioteraia stereotassica. S.Grespi, C.Menichelli, A.Fanelli, G.Pastore, C.Arricchiello, F.Casamassima. XXV National Congress AIRO. Rimini, 7-10 Novembar 2015 (Poster P208). Ruolo della radioterapia stereotassica nel trattamento delle metastasi ossee da cancro prostatico nel paziente ormonorefrattario. S.Grespi, C.Menichelli, A.Fanelli, G.Pastore, C.Arricchiello, F.Casamassima. XXV National Congress AIRO. Rimini, 7-10 Novembar 2015 (Poster P219). SBRT-VMAT monoisocentrica nel trattamento di metastasi epatiche multiple. G.Pastore, C.Menichelli, A.Fanelli, C.Arricchiello, S.Grespi, S.Tubin, F.Casamassima. XXV national Congress AIRO. Rimini, 7-10 Novembar 2015 (Poster P233).
La tecnica VMAT per il trattamento di metastasi polmonari multiple: pianificazione a singoloisocentro vs piani multi-isocentrici. C.Arricchiello, G.Pastore, C.Menichelli, A.Fanelli, S.Grespi, S.Tubin, F.Casamassima. XXV national Congress AIRO. Rimini, 7-10 Novembar 2015 (Poster P234). SBRT per lesioni secondarie epatiche e polmonari in 35 pazienti oligometastatici con eteroplasia mammaria. A.Fanelli, C.Menichelli, S.Tubin, S.Grespi, G.Pastore, C.Arricchiello, F.Casamassima. XXV National Congress AIRO. Rimini, 7-10 Novembar 2015 (Poster P235). Stereotactic radiotherapy for limited nodal relapse in prostate cancer. S.Grespi, F.Casamassima, C.Menichelli, A.Fanelli, S.Tubin,, G.Pastore, C.Arricchiello, A.Ferullo. 3 ESTRO Forum. Barcellona-Spain, April 2015 (Poster PO-0742). SBRT for CRC liver metastases: prognostic factors affecting LC and OS. C.Menichelli, F.Casamassima, I.Petrini, A.Fanelli, S.Grespi, S.Tubin,, G.Pastore, C.Arricchiello. 3 ESTRO Forum. Barcellona-Spain, April 2015 (Poster PO-0768). Trattamenti locali nel NSCLC oligometastatico: esperienza in 121 pazienti trattati con SBRT per le metastasi polmonari e surrenali che ed il primitivo polmonare localmente avanzato non operabile. S.Tubin, G.Salerno, A.Fanelli, S.Grespi,G.Pastore, C.Menichelli, F.Casamassima. XXIV National Congress AIRO. Padova, 8-11 Novembar 2014 (Poster P088). Radioterapia stereotassica (SBRT) nelle metastasi epatiche: risultati di 269 lesioni trattate. C.Menichelli, A.Fanelli, S.Tubin, S.Grespi, G.Pastore, F.Casamassima. XXIV National Congress AIRO. Padova, 8-11 Novembar 2014 (Poster P092). La re-irradiazione nei tumori del SNC. A.Fanelli, C.Menichelli, S.Tubin, S.Grespi, G.Pastore, A.Ferullo, F.Casamassima. XXIV National Congress AIRO. Padova, 8-11 Novembar 2014 (Poster P182). Tecnica VMAT monoisocentrica su principi radobiologici nel trattamento radio chirurgico di metastasi cerebrali multiple. - G.Pastore, C.Menichelli, A.Fanelli, S.Grespi, S.Tubin, F.Casamassima. XXIV National Congress AIRO. Padova, 8-11 Novembar 2014 (Poster P201). Trattamento SBRT per metastasi polmonari in pazienti oligometastatici: esperienza in 101 pazienti. S.Tubin, S.Grespi, A.Fanelli, C.Menichelli, F.Casamassima. XXIX National Congress AIRB, Florence 13-14 June 2014 (Oral Communication). Fingolimod (FTY720) sensitized breast cancer cells to Radiation Therapy. G.Marvaso, A.Barone, N.Amodio, V.Scotti, S.Grespi, M.T.Di Martino, P.Tagliaferri,P.Tassone, R.Bianco, C.Bianco. XXII National Congress AIRO. Roma, 17-20 Novembar 2012 (Poster).
Can dose intensification improve the outcome in SBRT? L'intensificazione della dose può migliorare i risultati in SBRT? V. Scotti, S. Grespi, V. d Alesio, L. Bottalico, P. Grosso, T. Petrone, A. D. Kirk,E. Colonna, C. Laudando C. Bianco XXII National Congress AIRO. Roma, 17-20 November 2012 (Poster). Interferon-based adjiuvant chemoradiation in patient whit resected pancreatic adenocarcinoma: a phase II/III study. M.Coppola,A.Sainato,A.Grandinetti,S.Grespi,U.Boggi,S.Mazzeo,E.Vasile,N.Cernusco,C.Greco,L.Cionini Tumori, Volume 10, Number 2, November 2010. Comparison of different radiotherapy techniques for the treatment of carcinomas of the anal canal. F.Matteucci, F.Pasqualetti, V.Scotti, S.Grespi, M.De Liguoro, V.Cerboneschi, A.Grandinetti, L.Forte, M.Coppola, L.Cionini Tumori, Volume 8, Number 1, November 2009. Risultati a lungo termine nei pazienti con recidiva di glioma maligno: una serie di casi. M.G.Fabrini, L.De Franco, F.Perrone, A.Grandinetti, V.Scotti, F.Pasqualetti, S.Grespi, R.Vannozzi, L.Cionini. Rivista medica, Volume 15, Suppl 2, September 2009. Cure the body and take care of the mind: Humanized hospital of radiotherapy of the Azienda Ospedaliera Pisana. M.Mancino, V.Scotti, S. Grespi, F.Matteucci, C.Berrocal, O.Bernini et al. XVIII National Congress AIRO. Milano, November 2008 (Poster). Feasibility study of an innovative Ir-192 HDR peri-operative brachytherapy treatment in focal recurrent malignant glioma. M.G. Fabrini, F.Perrone, R.Vannozzi, F.Pasqualetti, E.Peci, V.Scotti, S.Grespi, M.De Liguoro, A.Grandinetti, L.Cionini. Radiotherapy et Oncology, Journal of the European Society for Therapeutic radiology and Oncology Volume 88, Supplement 2, September 2008. Fotemustine as second line chemotherapy for recurrent glioblastoma (GBM): a multi-istitutional study. M.G. Fabrini, G.Silvano, A.R. Marsella, I.Logli, F.Perrone, A.Romanini, V.Scotti, S.Grespi, F.Pasqualetti, L.Cionini. XIII National Congress AINO. Roma, 2008 (Oral Communication). Adjuvant External Beam Radiotherapy for anaplastic Thyroid Carcinoma. A.Sainato, R.Elisei, P.Berti, P.Indrieri, S.Grespi, V. Cerboneschi, E. d Imporzano, Barison G. Tumori, Volume 5, Number 1, November 2007. External Beam Radiotherapy for loco-regional recurrences of differentiated thyroid carcinoma. A.Sainato, R.Elisei, P.Berti, B.Manfredi, P.Indrieri, S.Grespi, A.Grandinetti, F.Matteucci. Tumori, Volume 5, Number 1, November 2007.
Concurrent chemo-radiotherapy using highdose rate intracavitary brachytherapy in uterine cervical cancer. Fabrini MG, Pasqualetti F, Scotti V, Grespi S, Grandinetti A, De Liquoro M, Laliscia C, Gadducci A, Cionini L. Tumori Volume 5, Number 1, November 2007. Treatment of recurrent glioblastoma multiforme with fotemustine and bachitherapy. Pasqualetti F, Scotti V, Grandinetti A, Grespi S, Giraldi D, Fabrini MG, Romanini A, Vannozi R, Salvadori B, Ricci S, Cionini L. Annals of Oncology Volume 17, Supplement 11, 2006. Pisa, 26 June 2019 Silvia Grespi M.D.