PROGETTAZIONE MOLECOLARE PARTE B

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3 PROGETTAZIONE MOLECOLARE PARTE B Isttut d prvsta affrnza Isttut pr Matral Cmpst Bmdc Isttut d Mtdlg Chmch Isttut d Scnz Tcnlg Mlclar Isttut pr la Snts Organca la Ftrattvtà Isttut pr l Stud d Matral Nanstrutturat Isttut pr l Stud dll Macrmlcl Isttut pr la Tcnlga dll Mmbran

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5 Isttut pr matral cmpst bmdc Drttr: Sd prncpal: Artclazn trrtral: St wb dll'isttut: Dr. Ing. LUIGI AMBROSIO Pazzal Vncnz Tcch, Napl (NA) Szn d Psa Dpartmnt d prvsta affrnza Prgttazn Mlclar Mssn L'Isttut svlg attvtà d rcrca, valrzzazn trasfrmnt tcnlgc d frmazn n sgunt sttr scntfc rlatvamnt all sgunt tmatch: "Matral plmrc, cmpst nanstruttur cn carattrstch struttural funznal prgrammat"; "Tcnlg d prcss d plmr, cmpst nanstruttur"; "Matral plmrc cmpst pr l'nggnra d tssut mdcna rgnratva"; "Trasfrmnt tcnlgc". La mssn prncpal dll'isttut è l'accrscmnt dll cmptnz tcnc-scntfch pr l mantnmnt la prgrssn dl lvll d ccllnza nl sttr d matral cmpst plmrc nl sttr d bmatral, anch pr favrr l'mplmntazn dll cnscnz n nuv prdtt / prcss. In partclar, ssa è ntsa a svluppar sgunt punt: 1) Svluppar nuv cnscnz tcnc-scntfch nl sttr d matral cmpst a matrc plmrca fnalzzat all'nnvazn d matral dll rlatv tcnlg; 2) Favrr l'ntgrazn tra mprs d nt d rcrca al fn d svluppar una massa crtca pr l svlupp d cnscnz ch pssn dtrmnar un brakthrugh tcnlgc; 3) Favrr l trasfrmnt dll cnscnz svluppat a prcss prduttv attravrs cllabrazn cn mprs prvat dl sttr 4) Svlgr attvtà d frmazn d gvan rcrcatr all scp d favrr l trasfrmnt d cnscnz l'nsrmnt nl mnd dl lavr ad lvat valr aggunt; 5) Svlgr attvtà d dffusn d rsultat d rcrca attravrs pubblcazn, prsntazn a cnvgn ntrnaznal naznal, d rganzzazn d cngrss. 6) Svluppar rt naznal d ntrnaznal fnalzzat all svlupp d attvtà d rcrca su tmatch prrtar dll'ara cmun urpa. 7) Attrarr scnzat d fama mndal al fn d favrr l scamb d rcrcatr la frtlzzazn ncrcata dll cmptnz. Attvtà d rcrca (2010) Cmmss Plmr, cmpst nanstruttur cn prprtà funznal prgrammat Bmatral d nggnra d tssut Tcnlg d matral plmrc, cmpst nanstruttur Mdul mdul gstnal-cds051-pm Plmr, cmpst nanstruttur cn prprtà funznal prgrammat Bmatral d nggnra d tssut Tcnlg d matral plmrc, cmpst nanstruttur Stud d applcazn dll prprtà lttrnch d sld nanscpc

6 RSTL Rcrca lbra Rcrca lbra Stud dll'fftt mccanc chmc sull'ntrazn substrat plmrc cllul Rscaldamnt dlttrc nl prcssng d plmr Stud dlla dnamca dlla transzn vtrsa d flm ultrasttl plmrc. Crrlazn tra struttura prprtà d nancmpst plmrc funznal a bas d POSS Attvtà Cmmss Plmr, cmpst nanstruttur cn prprtà funznal prgrammat Prgtt: Dpartmnt: Rspnsabl: Sstm plmrc nanstrutturat, multcmpnnt mmbran pr applcazn funznal struttural Prgttazn Mlclar AMENDOLA EUGENIO Rsultat cnsgut ) Sstm trmndurnt. L'utlzz d nuv plammdstr prramfcat ha dtrmnat l mglramnt dll prprtà mccanch dlla tnactà dll rsn pssdch n cu sn stat nglbat. Nll'ambt dll applcazn arspazal sn stat ralzzat sstm pssdc ad lvata Tg lvata "ut-lf", cntrlland paramtr struttural qual grad d funznaltà md, ngmbr strc rgdtà d prcursr. ) Flm Mmbran. Pr quant cncrn matral pr l'mballagg almntar, sn stat ttnut flm attv ad azn antmcrbca mdant prcss d strusn. Tal matral pssn ssr mpgat cm flm flssbl cm vaschtt-cntntr pr l cnfznamnt d almnt frsch sggtt a dgradazn d tp mcrbc. Pr qul ch cncrn matral pr cll a cmbustbl, sn stat ralzzat mmbran brd a bas d Nafn ttnut mdant prcss sl-gl cn mglrat prprtà d cnducbltà prtnca ad lvata tmpratura. Sn nltr stat ralzzat mmbran nmrch altrnatv al Nafn attravrs la sulfnazn slttva dlla fas amrfa dl PS sndtattc. ) Plmr pr applcazn lttrnch. Sn stat ralzzat flm plmrc trasparnt cn rdtt cffcnt d spansn trmca lnar pr la prduzn d dsplay LCD. E' stat ralzzat un sstma cmpst brd mtall/rganc d nanfbr d planlna, gà nlla lr stat d ssdazn cnduttv, ch nglban nanpartcll d'r passvat cn ddcantl (Pan.CSA/ AuNPS) cn mglr prprtà lttrch rsptt a sstm smlar prsstnt basat su cnduttr rganc. Sn stat ralzzat fltr pr cll ftvltach csttut da matrc plmrch cntnnt napartcll d mtall nbl (r). A tal fn s è rscntrat cnvnnt l'mpg d pnt slfur (- S-) tra l'anll armatc la suprfc dl clustr. Ottm rsultat sn stat ttnut cn mdazl su drvat ssttut. v) Cmpst cn rnfrz natural. Sn stat ttnut matral cmpst ad lvat prstazn mccanch rnfrzand cn fbr d cllulsa / canapa matrc trmplastch qual PS cplmr EVA. Sn stat anch prparat cmpst a bas d mscl pllfn/plstr (PP/ MatrB, HDPE/MatrB, PS/MatrB) cn fbr natural (canapa, knaf), ttnut n prsnza d cmpatblzzant rattv d dvrs tp. v) Ibrd rganc-nrganc. Prparazn d nan cmpst a matrc pssdca mdant frmazn n stu d nan partcll d slc rgan-mdfcat cn mglrat prprtà trm mccanch. Tal matral manfstan un sddsfacnt cmprtamnt trm-mccanc cn Tg,

7 mdul lastc nlla rgn gmmsa stabltà trm-ssdatva suprr rsptt a matral nn nan strutturat. La carattrzzazn dffrattmtrca ha prmss d vdnzar ch la nanstruttura slssanca prdtta mdant apprcc sl-gl mdfca ntvlmnt la struttura mlclar dll rsn pssdch nl rang dll lunghzz carattrstch cmprs tra 80-20nm. Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Attvtà dtra l Prncpal cllabrazn Sn n crs cllabrazn d rcrca cn: Dpartmnt d Chmca, Unvrstà "Fdrc II" d Napl Dpartmnt d Inggnra d Matral dlla Prduzn, Unvrstà "Fdrc II" d Napl Dpartmnt d Chmca, d Farmaca, d Inggnra Chmca d Almntar dll'unvrstà dgl Stud d Salrn. Cntr d Cultura pr l Matr Plastch dl Pltcnc d Alssandra Dpartmnt d Chmca Chmca Ind.l, Unv. d Psa, Psa Dpartmnt d Inggnra Chmca Scnza d Matral, Unv. d Psa, Psa Unvrstà dgl Stud d Fgga, Dpartmnt d Scnza dgl Almnt. Unvrstà d Mssna; Unvrstà d Blgna; Unvrstà dlla Baslcata; Dstrtt d Rcrca d Matral Cmpst dll Struttur (IMAST), Prtc (NA) Isttut d Chmca Tcnlga d Plmr, ICTP-CNR, Pzzul Isttut Naznal d Santà, Prf. Ganan Calv, Unvrstà d Svgla Insttut d Scnc t d'ingénr Supramléculars (I.S.I.S.), Unvrsté d Strasburg (Franca); Swarthmr Cllg (Swarthmr PA, Stat Unt); Havrfrd Cllg (Havrfrd - PA, Stat Unt); Grupp d rcrca dl prf Masca dlla Lughbrugh Unvrsty, Lughbrugh (UK). Stat Ky Labratry f Plymr Matrals Engnrng, Schuan Unvrsty n Chngdu (Chna). Isttut Naznal d Santà, Dr. Rcard Jrg, Lsbna (Prtgall) Plsh Acadmy f Scncs, Ldz (Plna); Bulgaran Acadmy f Scnc Dpartmnt f Matrals Scnc Unvrsty f Alxandra (Egtt); Insttut f Plymrs, Bulgaran Acadmy f Scncs, Sfa (Bulgara); Rsarch Insttut n Nancmpst, Kyt Japan. Engnrng f Plymrc Matrals, INSA-CNRS, Lyn (Franca). Stat Ky Labratry f Plymrc Matrals Engnrng, Chngdu (Cna) Harbn Tchnlgy Insttut, Szhnzn (Chna) Cntr f Mlcular and Macrmlcular Studs, Plsh Acadmy f Scncs, Ldz (Plna) Insttut f Plymrs, Bulgaran Acadmy f Scncs, Sfa (Bulgara) Insttut d Invstgacns n Cnca y Tcnlga d Matrals (INTEMA), CONICET, Unvrsdad d Mar dl Plata, Argntna Rsarch Insttut f Cramc Phscs Lab, Dpt. f Chmstry and Matral Engnrng, Kyt Insttut f Tchnlgy (Japan) ENEA Cntr Rcrch Fat Elass; Alna Av Grups

8 Trm-PAIF S.p.A., Battpagla (SA) ST Mcrlctrncs. Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal 8 13 Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr 8 8 Ttal Prncpal rsrs strumntal utlzzat all'ntrn dll'sttut la maggr part dl lavr d carattrzzazn ncssar all attvtà d rcrca. La gamma è mlt ampa, cmprnd l stud dll prprtà mccanch lastch, ultm dnamc mccanch, mdant l'utlzz d dnammtr statc, msuratr d nrga d frattura, analzzatr dnamc-mccanc. Inltr la dspnbltà d una mdrna d accssrata pattafrma d nan ndntazn prmtt l stud dll prprtà vsclastch d flm sttl, l lr prprtà trblgch l stud dll'adsn su substrat. La carattrzzazn spttrscpca prmtt d nvstgar la cmpszn d sstm l prprtà ttch mdant spttrftmtr nfrarss, UV-vsbl d accppatr prsmatc pr l'dntfcazn dll'ndc d rfrazn. Un mcrscp IR d un mcrscp ttc sn utlzzat pr l stud mrflgc d matral. Un dffrattmtr a ragg X n bass d alt angl cmpltan ultrrmnt la gamma dll carattrzzazn. Sn dspnbl strumnt pr l stud dll prprtà trm analtch (calrmtra, trm gravmtra, dlatmtra) pr l stud d transzn d fas, d cntch d rtclazn dlla stabltà trm ssdatva. E' dspnbl un dffrattmtr a bass d amp angl (2tta nl rang tra 0 40 ) dtat d camra CCD pr l mntragg n "ral tm" d trasfrmazn tmp-tmpratura d matral. L strumnt è qupaggat cn hldrs pr flm, plvr past n grad d cntrllar la tmpratura fn a 120 C. Bmatral d nggnra d tssut Prgtt: Dpartmnt: Rspnsabl: Sstm plmrc nanstrutturat, multcmpnnt mmbran pr applcazn funznal struttural Prgttazn Mlclar DE SANTIS ROBERTO

9 Rsultat cnsgut Pr l prgtt cmuntar "DISC REGENERATION ": 1) Indvduazn dll frmulazn pù prmttnt pr la rgnrazn dl nucl dl dsc ntrvrtbral rlatv a gl sm-ipn a bas d cllagn, acd alurnc chtsan, gl d cllagn rnfrzat cn mcrsfr d glatna; 2) prprtà d nttabltà d tutt l frmulazn; 3) prprtà rlgch dll frmulazn prma dp nzn; 4) prgttazn d un mdll CAD d scaffld ttalmnt ntrcnnss pr la rgnrazn dll'anulus dsc ntrvrtbral; 5) ralzzazn d prttp d plug snttc pr la chusura dl fr pr l'accss attravrs l'anulus d sstm d nzn Pr l prgtt cmuntar "MAGISTER": 1 ralzzazn struttur 3D plmrch cn gmtra cubca csttut da un ntwrk d pr cn un grad d ntrcnnssn dl 100%; 2) dtrmnazn dll prprtà mrflgch, mccanch, d attrazn magntca blgch 3) l prv d small punch tst ndcan ch la prsnza d FHA al 10% n ps cmprta un aumnt dl mdul lastc dlla rsstnza, tal prprtà dmnuscn aumntand ultrrmnt la prcntual d FHA; 4) l'anals al mcrscp a scansn lasr mstra un mglramnt n trmn d adsn spradng cllular, rsptt a rsultat ttnut pr matral d sl PCL. Nll'ambt dl prgtt naznal "TssuNt" sn svluppat l sgunt attvtà: 1) ralzzazn carattrzzazn d scaffld cmpst n PEG/PCL PEG/HA mdant la tcnca d salt lachng n cmbnazn cn tcnch d ftplmrzzazn. 2) Carattrzzazn mrflgca d ttmzzazn dll mmbran lttrflat n PCL PCL/Glatna d ntrss applcatv nlla rgnrazn d tssut grarchcamnt rdnat qual ss nrv. In partclar, sstm nanstrutturat n PCL/glatna sn stat blgcamnt tstat mdant cltura n vtr d a) hmsc pr la rgnrazn ssa b) PC12 pr la rgnrazn dl nrv. 3) Ralzzazn d prttp d scafflds cmpst csttut da matrc n PCL funznalzzat mdant sgnal battv a bas d fsfat d calc (HA, MgHA) pr un mglramnt dll prprtà stgnch. Pr l prgtt naznal "MINUTA": 1) prttp d struttur 3D plmrch cmpst a mrflga cntrllata; 2) l'magng mdant SEM mcr CT ha mstrat ch l struttur hann un grad d ntrcnnssn dl 100% mrflga n accrd cn valr mpstat n fas d prcss; 3) prgttazn CAD d scaffld clndrc pr dftt stcndral pr gncch d pcra; 4) prgttazn CAD dl rcprmnt (mncpartmntal) dll'artclazn dl gncch d pcra. I rsultat nll'ambt dl prgtt naznal "matral pr la rgnrazn d tssut cranfaccal" (PRIN2007) hann prmss la mssa a punt d un prtcll unc n vtr pr prv blgch, mccanch, mrflgch chmc-fsch; ralzzazn d prttp d scafflds mdant salt lachng bplttr a bas d PCL plvr brd a d ttana d zrcna al 12%. I rsultat nll'ambt dl prgtt naznal PRIN2008 rguardan matral n frma d mmbrana ch sn stat carattrzzat stt l'asptt chmc, trmc mccanc. In partclar, sn stat analzzat ps mlclar d matral ttnut mdant crmatgrafa a prmazn su gl, l tmpratur d fusn transzn vtrsa l carattrstch mccanch mdant anals trmca-dnamc-mccanca. Nll'ambt d prgtt d rcrca blatral fra Itala d Egtt annualtà dl mnstr dgl str "Vsclastc and njctn prprts f njctabl chtsan/calcum phsphats cmpsts wth antbactral and antmcrbal functns" rsultat rguardan l'ttmzzazn d gl n manra ch la glfcazn avvnss alla tmpratura crpra n md ttnr matral nttabl. Nll'ambt dl prgtt MERIT "Mdll nnvatv d rparazn rgnrazn d tssut n traum rtpdc" s è avvata la prgttazn la carattrzzazn chmc fsca d pattafrm nanstrutturat mdant tcnch d lttrflatura ad lvata anstrpa struttural, n grad d frnr una guda mrflgca alla frmazn d nuv tssut pr la rgnrazn d tssut rntat qual muscl nrv. Nll'ambt dl cntratt d rcrca "Hyalurnc acd basd hydrgls and and hyalurnc acd drvatvs at mcr and macr-scal f rgnrratv mdcn and drug dlvry applcatns" rsultat rguardan la dtrmnazn dll prprtà chmc-fsch drgl lr ttmzzazn pr applcazn nll'accrscmnt d tssut sffc, qual l drma crd vcal. I rsultat nll'ambt dl cntratt d rcrca "SLER" vdnzan ch l nuv prcss d ftplmrzzazn prmtt d smrzar gl strss ch s gnran durant la ftplmrzzazn.

10 Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Attvtà dtra l Prncpal cllabrazn Nll'ambt dl prgtt cmuntar "DISC REGENERATION" l cllabrazn sn cn sgunt sttut: Fda Advancd Bplymrs s.r.l. FAB Italy; Unvrstätssptal Basl USB Swtzrland; Unvrsty f Brghtn UB UK; Jhanns Gutnbrg Unvrstät Manz JGU Grmany; Insttut Nacnal d Engnhara Bmédca INEB Prtugal; Insttut d Bngnyra d Catalunya IBEC Span; Swra IVF AB IVF Swdn; Natnal Unvrsty f Irland, Galway NUIG Irland; Unvrsty f Ulm UULM Grmany; Unvrsty f Alcant UA Span; Unvrstà d Padva UNIPD Italy; Unvrsty Plthnca Bucharst UPB Rmana; Kng's Cllg L ndn KCL UK; Unvrsdad d Mnh 3B's-UM Prtugal; SAMO s.p.a. SAMO Italy; Kathlk Unvrstt Luvn K.U.Luvn Blgum. Nll'ambt dl prgtt cmuntar "MAGISTER" l cllabrazn sn fra: CNR-ISTEC Isttut d Scnza Tcnlga d Matral Cramc, Blgna; IOR Isttut Ortpdc Rzzl, Blgna; Unvrsty f Hdlbrg, Grmany; Unvrsdad Pltécnca d Valnca, Span; Unvrsdad d Santag d Cmpstla, Span; BIO-VAC España, SA; Frschungszntrum Drsdn - Rssndrf FZD D, Grmany; Matrals Scnc & Tchnlgy, Swtzrland; Unvrsty f Ednburgh UK; Unvrsty f Zagrb; Unvrsty Hsptal Basl Swtzrland; INVENT INV, Italy; I+ I+ I, Italy; Bdvc Systms; Blarussan Stat Mdcal Unvrsty; Explra S.r.l. Italy, AvantCll Scnc Ltd ACS UK; Cntral Insttut f Orthpdcs and Traumatlgy f Russa; Unvrsty f Brghtn UB, UK. Nll'ambt dl prgtt naznal FIRB "TISSUENET" l cllabrazn sn fra sgunt sttut: Intrdscplnary Rsarch Cntr n Bmatrals CRIB, Advancd Btchnlgy Cntr CBA, Dpartmnt f Innvatn Engnrng Unvrsty f Salnt, San Raffal Hsptal Scntfc Insttut ISSR, Insttut fr Bmdcal Tchnlgs ITB-CNR, Insttut f Scnc and Tchnlgy fr Cramcs ISTEC-CNR, Dpartmnt f Exprmntal Mdcn and Pathlgy Unvrsty f Rm, Srvc f Exprmntal Surgry Rzzl Orthpadc Insttut. Nll'ambt dl prgtt naznal FIRB "MINUTA" l cllabrazn sn fra: CNR-ISTEC Isttut d Scnza Tcnlga d Matral Cramc, Blgna; IOR Isttut Ortpdc Rzzl, Blgna; Isttut d Gntca Mdca - CNR, Szn d Blgna; Unvrstà d Blgna: Dp d Scnz Anatmch; NNL - Labratr Naznal d Nantcnlg; Unvrstà d Gnva: Dp. d Mdcna Sprmntal; Unvrstà d Gnva: Dp. d Chmca Tcnlg Farmacutch d Almntar; Unvrstà d Gnva: Dp. d Fsca; Unvrstà d Mlan-Bccca: Dp. d Btcnlg Bscnz; Fncramca Fanza Nll'ambt dl Prgtt Naznal PRIN2007 l cllabrazn sn fra sgunt sttut dpartmnt: Unvrstà Fdrc II d Napl Dpartmnt d Scnz Odntstmatlgch maxll faccal, DIAM-SUN d Avrsa, Unvrstà d Frrara facltà d'nggnra. Nll'ambt dl Prgtt Naznal PRIN2008 l cllabrazn sn cn l Dpartmnt d Inggnra Chmca dll'unvrstà d Psa. Nll'ambt d prgtt d rcrca blatral fra Itala d Egtt annualtà dl mnstr dgl str "Vsclastc and njctn prprts f njctabl chtsan/calcum phsphats cmpsts wth antbactral and antmcrbal functns" l cllabrazn sn cn l Cntr d rcrca ntrdscplnar su bmatral "Unvrstà dgl stud d Napl FdrcII" lìunvrstà gzana dl Car. Nll'ambt dl prgtt MERIT l cllabrazn sn cn l'isttut d Gntca Bfsca dl CNR d Napl. Nll'ambt dl cntratt d rcrca "Hyalurnc acd basd hydrgls and and hyalurnc acd drvatvs at mcr and macr-scal f rgnrratv mdcn and drug dlvry applcatns" l cllabrazn sn cn Nvzyms Bplymr A/S, Danmarca d l Cntr d rcrca

11 ntrdscplnar su bmatral "Unvrstà dgl stud d Napl Fdrc II". Nll'ambt dl prgtt SLER l cllabrazn sn cn la Mctrn spa d l Dpartmnt d scnz dntstmatlgch maxll-faccal dll'unvrstà dgl stud d Napl Fdrc II Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal 7 13 Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr Ttal Prncpal rsrs strumntal utlzzat RISORSE DI CARATTERIZZAZIONE CHIMICA, FCA, MECCANICA, TERMICA, BIOLOGICA L rsrs d carattrzzazn rlgca cmprndn dvrs apparcchatur qual rmtr vscsmtr (Rmtr Bhln, Vscsmtr a capllar, rmtr rtaznal, apparat pr msur mcrrlgch) pr msur rlgch su scala macr mcr d plmr cmpst (macr, mcr nanrnfrzat). L rsrs strumntal d carattrzzazn mccanca cmprndn dvrs apparcchatur dnammtrch (Instrn, MTS, Bs) d natura mccanca, draulca d lttrmagntca pr sgur prv statch dnamch su plmr cmpst pr applcazn bmdcal pr l'nggnra d tssut. L'Instrn draulca è qupaggata cn camra trmca (raffrddata ad azt rscaldata lttrcamnt), mntr dnammtr MTS bs sn qupaggat cn camra ambntal pr smular ambnt umd trmcntrllat. L rsrs strumntal d magng 3D ntrssan scannr LASER (Cybrwar Plhmus) utlzzat pr rlvar suprfc trdmnsnal cmplss d dspstv bmdcal. L rsrs strumntal rlatv all msur dmnsnal d dfrmazn rguardan apparcchatur pr la msura dll dmnsn d partcll, apparcchatur ttch pr la msura d dfrmazn apparcchatur pr msur lcal d dfrmazn mdant stnsmtr a francbll. L rsrs strumntal rlatv a sstm d acquszn dat (Natnal Instrumnts StranSmart) sn mpgat pr l'acquszn smultana d sgnal lttrc prvnnt da snsr (trmcpp, sgnal DC d AC, stnsmtr, tc.). L rsrs strumntal rlatv alla bstmlazn rguardan du brattr Bs assal (un pr tssut dur l'altr pr tssut dns) d un brattr a 10 camr trsnal. Qust apparcchatur sn utlzzat pr analzzar gl fftt dlla stmlazn mccanca sull'vluzn n vtr d scaffld smnat cn cllul. RISORSE STRUMENTALI DI PROCESSO L rsrs strumntal d prcss rguardan apparcchatur pr la prttpazn rapda qual la

12 stampant pr ftplmrzzazn 3D (nvsntc) d l bplttr (Envsntc). Qust apparcchatur sn utlzzat pr la ralzzazn d scafflds trdmnsnal standardzzazt custm mad a prstà cntrllata d ntrcnnssa d matral plmrc, cmpst nancmpst pr l'nggnra d tssut. Capp chmch sn rsrs n cu snttzzar plmr cmpst pr la ralzzazn d bmatral scaffld avvalnds d tcnch d salt lachng, sparazn d fas, slvnt castng, spss snttzzat n stamp 3D rcavat mdant prttpazn rapda. L'lttrspnnng è un'apparcchatura d prcss pr ralzzar sstm prvalntmnt bdmnsnal cn carattrstch nanmtrch tal da rprdurr l'rganzzazn struttural d matrc xtracllular. RISORSE DI PROGETTAZIONE L rsrs strumntal d prgttazn assstta al calclatr rguardan sftwar qual Rhncrs, Mmcs d Ansys. Sn utlzzat pr prgttar l CAD d bmatral scafflds pr l'nggnra d tssut pr sgur smulazn mccanch. Tcnlg d matral plmrc, cmpst nanstruttur Prgtt: Dpartmnt: Rspnsabl: Sstm plmrc nanstrutturat, multcmpnnt mmbran pr applcazn funznal struttural Prgttazn Mlclar GIORDANO MICHELE Rsultat cnsgut Rsptt agl bttv d cmmssa: 1)Lamnat bdgradabl ttnut a partr da prtn trmplastch. 2)Ralzzazn d matrc pssdch, carcat cn nantub d carbn, cn prprtà mccanch d lttrch mglrat. Mdllazn mrflgca multscala d mccansm d cnduzn lttrca n nancmpst a bas d nan tub d carbn. Mdllazn dll prprtà mccanch d nancmpst a bas d nantub d carbn. Indvduazn dll crrlazn tra mrflga d nancmpst carattrstch d nantub (quanttatv d "aspct rat"). Carattrzzazn trm mccanca d mcr nan cmpst. Svlupp carattrzzazn d sstm cmpst basat su matrc trmplastch ad lvat prstazn pr mpgh ad alta tmpratura (PEN PES) d n cndzn. 3) Mdll pr l'mprgnazn d tw n fbra scca passant stt rull. Mssa a punt dl prcss d manfattura d lmnt cmplss (gmtra nn pana, dppa curvatura) n matral cmpst. Mssa a punt dl prcss d nfusn d matral cmpst brd multstrat 4) Svlupp d sstm nan / mcr cmpst spans basat su matrc ad alt prstazn (PEN, PES) carch nanmtrch (nanplvr d slc, graft spansa). Svlupp d matral brd rganc-nrganc, a matrc plurtanca carch cramch mtallch. Carattrzzazn d ttmzzazn d sstm nan/mcrcmpst spans basat su matrc ad alt prstazn (PEN, PES) carch nanmtrch (nanplvr d slc, graft spansa). Stud d sstm sandwch mnmatrc cn strat strn rnfrzat n fbra d vtr d spansn dll strat ntrn tramt tcnlga n-stu. Carattrzzazn d ttmzzazn d matral brd rganc-nrganc, a matrc plurtanca carch cramch mtallch 5) Mssa a punt d catng pr la bsnsrstca basat su badsv cplmr snttc. Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Attvtà dtra l

13 Prncpal cllabrazn CERN: Structural Halth Mntrng Camattn/Av/Elass/TPPA/MTA: nuv trmplastc ORv: spans nancarcata matrc trmplastca IMAST/Alna/Unvrstà d Napl "Fdrc II": Cmpst brd pr l smrzamnt acustc ARGOM/ Unvrstà d Napl "Fdrc II": Nuv lastmr trmplastc nancarcat Prgtt IP urp NvlQ (Isttut Svds pr la Tcnlga Almntar, Unvrstà d Mntpllr, CSIR-Suth Afrca, INTI-Argntna) IMAST/Bng/Elass: Svlupp d matral cmpst struttural a matrc trmplastca IMAST/Bng: Svlupp d schum trmplastch ad lvat prstazn TECNOPOL: Svlupp d plurtan spans lttrcnduttv Unvrstà d Napl "Fdrc II": Nuv tcnlg d nfusn Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal 6 10 Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr 5 5 Prncpal rsrs strumntal utlzzat Carattrzzazn struttural (WAX SAX) Carattrzzazn trmca (DSC, DMA, TGA) Carattrzzazn mccanca statca dnamca Carattrzzazn rlgca n rgm staznar d scllatr Carattrzzazn al fuc (Cn calrmtr, Mcrcalrmtr) Stampagg a cmprssn Msclatr d strusr pr fus plmrc Sstm d spansn n batch Sncatr Spttrftmtr UV Mcrscpa ttca d lttrnca Ansys, Cmsl Multphyscs, MdFrntr, Matlab Vd sstma pr l'anals dll crcch Ttal Attvtà Mdul

14 mdul gstnal-cds051-pm Cmmssa: Prgtt: Dpartmnt: Rspnsabl: Cmmssa gstnal pr sttut PM Prgtt pr CDS 506 Dpartmnt Prgttazn Mlclar Prgttazn Mlclar AMBROSIO LUIGI Rsultat cnsgut Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Prncpal cllabrazn Attvtà dtra l Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr Ttal Plmr, cmpst nanstruttur cn prprtà funznal prgrammat Cmmssa: Prgtt: Dpartmnt: Rspnsabl: Plmr, cmpst nanstruttur cn prprtà funznal prgrammat Sstm plmrc nanstrutturat, multcmpnnt mmbran pr applcazn funznal struttural Prgttazn Mlclar AMENDOLA EUGENIO Rsultat cnsgut

15 ) Sstm trmndurnt. L'utlzz d nuv plammdstr prramfcat ha dtrmnat l mglramnt dll prprtà mccanch dlla tnactà dll rsn pssdch n cu sn stat nglbat. Nll'ambt dll applcazn arspazal sn stat ralzzat sstm pssdc ad lvata Tg lvata "ut-lf", cntrlland paramtr struttural qual grad d funznaltà md, ngmbr strc rgdtà d prcursr. ) Flm Mmbran. Pr quant cncrn matral pr l'mballagg almntar, sn stat ttnut flm attv ad azn antmcrbca mdant prcss d strusn. Tal matral pssn ssr mpgat cm flm flssbl cm vaschtt-cntntr pr l cnfznamnt d almnt frsch sggtt a dgradazn d tp mcrbc. Pr qul ch cncrn matral pr cll a cmbustbl, sn stat ralzzat mmbran brd a bas d Nafn ttnut mdant prcss sl-gl cn mglrat prprtà d cnducbltà prtnca ad lvata tmpratura. Sn nltr stat ralzzat mmbran nmrch altrnatv al Nafn attravrs la sulfnazn slttva dlla fas amrfa dl PS sndtattc. ) Plmr pr applcazn lttrnch. Sn stat ralzzat flm plmrc trasparnt cn rdtt cffcnt d spansn trmca lnar pr la prduzn d dsplay LCD. E' stat ralzzat un sstma cmpst brd mtall/rganc d nanfbr d planlna, gà nlla lr stat d ssdazn cnduttv, ch nglban nanpartcll d'r passvat cn ddcantl (Pan.CSA/ AuNPS) cn mglr prprtà lttrch rsptt a sstm smlar prsstnt basat su cnduttr rganc. Sn stat ralzzat fltr pr cll ftvltach csttut da matrc plmrch cntnnt napartcll d mtall nbl (r). A tal fn s è rscntrat cnvnnt l'mpg d pnt slfur (- S-) tra l'anll armatc la suprfc dl clustr. Ottm rsultat sn stat ttnut cn mdazl su drvat ssttut. v) Cmpst cn rnfrz natural. Sn stat ttnut matral cmpst ad lvat prstazn mccanch rnfrzand cn fbr d cllulsa / canapa matrc trmplastch qual PS cplmr EVA. Sn stat anch prparat cmpst a bas d mscl pllfn/plstr (PP/ MatrB, HDPE/MatrB, PS/MatrB) cn fbr natural (canapa, knaf), ttnut n prsnza d cmpatblzzant rattv d dvrs tp. v) Ibrd rganc-nrganc. Prparazn d nan cmpst a matrc pssdca mdant frmazn n stu d nan partcll d slc rgan-mdfcat cn mglrat prprtà trm mccanch. Tal matral manfstan un sddsfacnt cmprtamnt trm-mccanc cn Tg, mdul lastc nlla rgn gmmsa stabltà trm-ssdatva suprr rsptt a matral nn nan strutturat. La carattrzzazn dffrattmtrca ha prmss d vdnzar ch la nanstruttura slssanca prdtta mdant apprcc sl-gl mdfca ntvlmnt la struttura mlclar dll rsn pssdch nl rang dll lunghzz carattrstch cmprs tra 80-20nm. Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Attvtà dtra l Prncpal cllabrazn Sn n crs cllabrazn d rcrca cn: Dpartmnt d Chmca, Unvrstà "Fdrc II" d Napl Dpartmnt d Inggnra d Matral dlla Prduzn, Unvrstà "Fdrc II" d Napl Dpartmnt d Chmca, d Farmaca, d Inggnra Chmca d Almntar dll'unvrstà dgl Stud d Salrn. Cntr d Cultura pr l Matr Plastch dl Pltcnc d Alssandra Dpartmnt d Chmca Chmca Ind.l, Unv. d Psa, Psa Dpartmnt d Inggnra Chmca Scnza d Matral, Unv. d Psa, Psa Unvrstà dgl Stud d Fgga, Dpartmnt d Scnza dgl Almnt. Unvrstà d Mssna; Unvrstà d Blgna;

16 Unvrstà dlla Baslcata; Dstrtt d Rcrca d Matral Cmpst dll Struttur (IMAST), Prtc (NA) Isttut d Chmca Tcnlga d Plmr, ICTP-CNR, Pzzul Isttut Naznal d Santà, Prf. Ganan Calv, Unvrstà d Svgla Insttut d Scnc t d'ingénr Supramléculars (I.S.I.S.), Unvrsté d Strasburg (Franca); Swarthmr Cllg (Swarthmr PA, Stat Unt); Havrfrd Cllg (Havrfrd - PA, Stat Unt); Grupp d rcrca dl prf Masca dlla Lughbrugh Unvrsty, Lughbrugh (UK). Stat Ky Labratry f Plymr Matrals Engnrng, Schuan Unvrsty n Chngdu (Chna). Isttut Naznal d Santà, Dr. Rcard Jrg, Lsbna (Prtgall) Plsh Acadmy f Scncs, Ldz (Plna); Bulgaran Acadmy f Scnc Dpartmnt f Matrals Scnc Unvrsty f Alxandra (Egtt); Insttut f Plymrs, Bulgaran Acadmy f Scncs, Sfa (Bulgara); Rsarch Insttut n Nancmpst, Kyt Japan. Engnrng f Plymrc Matrals, INSA-CNRS, Lyn (Franca). Stat Ky Labratry f Plymrc Matrals Engnrng, Chngdu (Cna) Harbn Tchnlgy Insttut, Szhnzn (Chna) Cntr f Mlcular and Macrmlcular Studs, Plsh Acadmy f Scncs, Ldz (Plna) Insttut f Plymrs, Bulgaran Acadmy f Scncs, Sfa (Bulgara) Insttut d Invstgacns n Cnca y Tcnlga d Matrals (INTEMA), CONICET, Unvrsdad d Mar dl Plata, Argntna Rsarch Insttut f Cramc Phscs Lab, Dpt. f Chmstry and Matral Engnrng, Kyt Insttut f Tchnlgy (Japan) ENEA Cntr Rcrch Fat Elass; Alna Av Grups Trm-PAIF S.p.A., Battpagla (SA) ST Mcrlctrncs. Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal 8 13 Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr 8 8 Ttal

17 Bmatral d nggnra d tssut Cmmssa: Prgtt: Dpartmnt: Rspnsabl: Bmatral d nggnra d tssut Sstm plmrc nanstrutturat, multcmpnnt mmbran pr applcazn funznal struttural Prgttazn Mlclar DE SANTIS ROBERTO Rsultat cnsgut Pr l prgtt cmuntar "DISC REGENERATION ": 1) Indvduazn dll frmulazn pù prmttnt pr la rgnrazn dl nucl dl dsc ntrvrtbral rlatv a gl sm-ipn a bas d cllagn, acd alurnc chtsan, gl d cllagn rnfrzat cn mcrsfr d glatna; 2) prprtà d nttabltà d tutt l frmulazn; 3) prprtà rlgch dll frmulazn prma dp nzn; 4) prgttazn d un mdll CAD d scaffld ttalmnt ntrcnnss pr la rgnrazn dll'anulus dsc ntrvrtbral; 5) ralzzazn d prttp d plug snttc pr la chusura dl fr pr l'accss attravrs l'anulus d sstm d nzn Pr l prgtt cmuntar "MAGISTER": 1 ralzzazn struttur 3D plmrch cn gmtra cubca csttut da un ntwrk d pr cn un grad d ntrcnnssn dl 100%; 2) dtrmnazn dll prprtà mrflgch, mccanch, d attrazn magntca blgch 3) l prv d small punch tst ndcan ch la prsnza d FHA al 10% n ps cmprta un aumnt dl mdul lastc dlla rsstnza, tal prprtà dmnuscn aumntand ultrrmnt la prcntual d FHA; 4) l'anals al mcrscp a scansn lasr mstra un mglramnt n trmn d adsn spradng cllular, rsptt a rsultat ttnut pr matral d sl PCL. Nll'ambt dl prgtt naznal "TssuNt" sn svluppat l sgunt attvtà: 1) ralzzazn carattrzzazn d scaffld cmpst n PEG/PCL PEG/HA mdant la tcnca d salt lachng n cmbnazn cn tcnch d ftplmrzzazn. 2) Carattrzzazn mrflgca d ttmzzazn dll mmbran lttrflat n PCL PCL/Glatna d ntrss applcatv nlla rgnrazn d tssut grarchcamnt rdnat qual ss nrv. In partclar, sstm nanstrutturat n PCL/glatna sn stat blgcamnt tstat mdant cltura n vtr d a) hmsc pr la rgnrazn ssa b) PC12 pr la rgnrazn dl nrv. 3) Ralzzazn d prttp d scafflds cmpst csttut da matrc n PCL funznalzzat mdant sgnal battv a bas d fsfat d calc (HA, MgHA) pr un mglramnt dll prprtà stgnch. Pr l prgtt naznal "MINUTA": 1) prttp d struttur 3D plmrch cmpst a mrflga cntrllata; 2) l'magng mdant SEM mcr CT ha mstrat ch l struttur hann un grad d ntrcnnssn dl 100% mrflga n accrd cn valr mpstat n fas d prcss; 3) prgttazn CAD d scaffld clndrc pr dftt stcndral pr gncch d pcra; 4) prgttazn CAD dl rcprmnt (mncpartmntal) dll'artclazn dl gncch d pcra. I rsultat nll'ambt dl prgtt naznal "matral pr la rgnrazn d tssut cranfaccal" (PRIN2007) hann prmss la mssa a punt d un prtcll unc n vtr pr prv blgch, mccanch, mrflgch chmc-fsch; ralzzazn d prttp d scafflds mdant salt lachng bplttr a bas d PCL plvr brd a d ttana d zrcna al 12%. I rsultat nll'ambt dl prgtt naznal PRIN2008 rguardan matral n frma d mmbrana ch sn stat carattrzzat stt l'asptt chmc, trmc mccanc. In partclar, sn stat analzzat ps mlclar d matral ttnut mdant crmatgrafa a prmazn su gl, l tmpratur d fusn transzn vtrsa l carattrstch mccanch mdant anals trmca-dnamc-mccanca. Nll'ambt d prgtt d rcrca blatral fra Itala d Egtt annualtà dl mnstr dgl str "Vsclastc and njctn prprts f njctabl chtsan/calcum phsphats cmpsts wth antbactral and antmcrbal functns" rsultat rguardan l'ttmzzazn d gl n manra ch la glfcazn avvnss alla tmpratura crpra n md ttnr matral nttabl. Nll'ambt dl prgtt MERIT "Mdll nnvatv d rparazn rgnrazn d tssut n traum

18 rtpdc" s è avvata la prgttazn la carattrzzazn chmc fsca d pattafrm nanstrutturat mdant tcnch d lttrflatura ad lvata anstrpa struttural, n grad d frnr una guda mrflgca alla frmazn d nuv tssut pr la rgnrazn d tssut rntat qual muscl nrv. Nll'ambt dl cntratt d rcrca "Hyalurnc acd basd hydrgls and and hyalurnc acd drvatvs at mcr and macr-scal f rgnrratv mdcn and drug dlvry applcatns" rsultat rguardan la dtrmnazn dll prprtà chmc-fsch drgl lr ttmzzazn pr applcazn nll'accrscmnt d tssut sffc, qual l drma crd vcal. I rsultat nll'ambt dl cntratt d rcrca "SLER" vdnzan ch l nuv prcss d ftplmrzzazn prmtt d smrzar gl strss ch s gnran durant la ftplmrzzazn. Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Attvtà dtra l Prncpal cllabrazn Nll'ambt dl prgtt cmuntar "DISC REGENERATION" l cllabrazn sn cn sgunt sttut: Fda Advancd Bplymrs s.r.l. FAB Italy; Unvrstätssptal Basl USB Swtzrland; Unvrsty f Brghtn UB UK; Jhanns Gutnbrg Unvrstät Manz JGU Grmany; Insttut Nacnal d Engnhara Bmédca INEB Prtugal; Insttut d Bngnyra d Catalunya IBEC Span; Swra IVF AB IVF Swdn; Natnal Unvrsty f Irland, Galway NUIG Irland; Unvrsty f Ulm UULM Grmany; Unvrsty f Alcant UA Span; Unvrstà d Padva UNIPD Italy; Unvrsty Plthnca Bucharst UPB Rmana; Kng's Cllg L ndn KCL UK; Unvrsdad d Mnh 3B's-UM Prtugal; SAMO s.p.a. SAMO Italy; Kathlk Unvrstt Luvn K.U.Luvn Blgum. Nll'ambt dl prgtt cmuntar "MAGISTER" l cllabrazn sn fra: CNR-ISTEC Isttut d Scnza Tcnlga d Matral Cramc, Blgna; IOR Isttut Ortpdc Rzzl, Blgna; Unvrsty f Hdlbrg, Grmany; Unvrsdad Pltécnca d Valnca, Span; Unvrsdad d Santag d Cmpstla, Span; BIO-VAC España, SA; Frschungszntrum Drsdn - Rssndrf FZD D, Grmany; Matrals Scnc & Tchnlgy, Swtzrland; Unvrsty f Ednburgh UK; Unvrsty f Zagrb; Unvrsty Hsptal Basl Swtzrland; INVENT INV, Italy; I+ I+ I, Italy; Bdvc Systms; Blarussan Stat Mdcal Unvrsty; Explra S.r.l. Italy, AvantCll Scnc Ltd ACS UK; Cntral Insttut f Orthpdcs and Traumatlgy f Russa; Unvrsty f Brghtn UB, UK. Nll'ambt dl prgtt naznal FIRB "TISSUENET" l cllabrazn sn fra sgunt sttut: Intrdscplnary Rsarch Cntr n Bmatrals CRIB, Advancd Btchnlgy Cntr CBA, Dpartmnt f Innvatn Engnrng Unvrsty f Salnt, San Raffal Hsptal Scntfc Insttut ISSR, Insttut fr Bmdcal Tchnlgs ITB-CNR, Insttut f Scnc and Tchnlgy fr Cramcs ISTEC-CNR, Dpartmnt f Exprmntal Mdcn and Pathlgy Unvrsty f Rm, Srvc f Exprmntal Surgry Rzzl Orthpadc Insttut. Nll'ambt dl prgtt naznal FIRB "MINUTA" l cllabrazn sn fra: CNR-ISTEC Isttut d Scnza Tcnlga d Matral Cramc, Blgna; IOR Isttut Ortpdc Rzzl, Blgna; Isttut d Gntca Mdca - CNR, Szn d Blgna; Unvrstà d Blgna: Dp d Scnz Anatmch; NNL - Labratr Naznal d Nantcnlg; Unvrstà d Gnva: Dp. d Mdcna Sprmntal; Unvrstà d Gnva: Dp. d Chmca Tcnlg Farmacutch d Almntar; Unvrstà d Gnva: Dp. d Fsca; Unvrstà d Mlan-Bccca: Dp. d Btcnlg Bscnz; Fncramca Fanza Nll'ambt dl Prgtt Naznal PRIN2007 l cllabrazn sn fra sgunt sttut dpartmnt: Unvrstà Fdrc II d Napl Dpartmnt d Scnz Odntstmatlgch maxll faccal, DIAM-SUN d Avrsa, Unvrstà d Frrara facltà d'nggnra. Nll'ambt dl Prgtt Naznal PRIN2008 l cllabrazn sn cn l Dpartmnt d Inggnra

19 Chmca dll'unvrstà d Psa. Nll'ambt d prgtt d rcrca blatral fra Itala d Egtt annualtà dl mnstr dgl str "Vsclastc and njctn prprts f njctabl chtsan/calcum phsphats cmpsts wth antbactral and antmcrbal functns" l cllabrazn sn cn l Cntr d rcrca ntrdscplnar su bmatral "Unvrstà dgl stud d Napl FdrcII" lìunvrstà gzana dl Car. Nll'ambt dl prgtt MERIT l cllabrazn sn cn l'isttut d Gntca Bfsca dl CNR d Napl. Nll'ambt dl cntratt d rcrca "Hyalurnc acd basd hydrgls and and hyalurnc acd drvatvs at mcr and macr-scal f rgnrratv mdcn and drug dlvry applcatns" l cllabrazn sn cn Nvzyms Bplymr A/S, Danmarca d l Cntr d rcrca ntrdscplnar su bmatral "Unvrstà dgl stud d Napl Fdrc II". Nll'ambt dl prgtt SLER l cllabrazn sn cn la Mctrn spa d l Dpartmnt d scnz dntstmatlgch maxll-faccal dll'unvrstà dgl stud d Napl Fdrc II Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal 7 13 Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr Ttal Tcnlg d matral plmrc, cmpst nanstruttur Cmmssa: Prgtt: Dpartmnt: Rspnsabl: Tcnlg d matral plmrc, cmpst nanstruttur Sstm plmrc nanstrutturat, multcmpnnt mmbran pr applcazn funznal struttural Prgttazn Mlclar GIORDANO MICHELE Rsultat cnsgut Rsptt agl bttv d cmmssa: 1)Lamnat bdgradabl ttnut a partr da prtn trmplastch 2)Ralzzazn d matrc pssdch, carcat cn nantub d carbn, cn prprtà mccanch d lttrch mglrat. Mdllazn mrflgca multscala d mccansm d cnduzn lttrca n nancmpst a bas d nan tub d carbn. Mdllazn dll prprtà

20 mccanch d nancmpst a bas d nantub d carbn. Indvduazn dll crrlazn tra mrflga d nancmpst carattrstch d nantub (quanttatv d "aspct rat"). Carattrzzazn trm mccanca d mcr nan cmpst. Svlupp carattrzzazn d sstm cmpst basat su matrc trmplastch ad lvat prstazn pr mpgh ad alta tmpratura (PEN PES) d n cndzn. 3) Mdll pr l'mprgnazn d tw n fbra scca passant stt rull. Mssa a punt dl prcss d manfattura d lmnt cmplss (gmtra nn pana, dppa curvatura) n matral cmpst. Mssa a punt dl prcss d nfusn d matral cmpst brd multstrat 4) Svlupp d sstm nan / mcr cmpst spans basat su matrc ad alt prstazn (PEN, PES) carch nanmtrch (nanplvr d slc, graft spansa). Svlupp d matral brd rganc-nrganc, a matrc plurtanca carch cramch mtallch. Carattrzzazn d ttmzzazn d sstm nan/mcrcmpst spans basat su matrc ad alt prstazn (PEN, PES) carch nanmtrch (nanplvr d slc, graft spansa). Stud d sstm sandwch mnmatrc cn strat strn rnfrzat n fbra d vtr d spansn dll strat ntrn tramt tcnlga n-stu. Carattrzzazn d ttmzzazn d matral brd rganc-nrganc, a matrc plurtanca carch cramch mtallch 5) Mssa a punt d catng pr la bsnsrstca basat su badsv cplmr snttc. Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Prncpal cllabrazn CERN: Structural Halth Mntrng Camattn/Av/Elass/TPPA/MTA: nuv trmplastc ORv: spans nancarcata matrc trmplastca IMAST/Alna/Unvrstà d Napl "Fdrc II": Cmpst brd pr l smrzamnt acustc ARGOM/ Unvrstà d Napl "Fdrc II": Nuv lastmr trmplastc nancarcat Prgtt IP urp NvlQ (Isttut Svds pr la Tcnlga Almntar, Unvrstà d Mntpllr, CSIR-Suth Afrca, INTI-Argntna) IMAST/Bng/Elass: Svlupp d matral cmpst struttural a matrc trmplastca IMAST/Bng: Svlupp d schum trmplastch ad lvat prstazn TECNOPOL: Svlupp d plurtan spans lttrcnduttv Unvrstà d Napl "Fdrc II": Nuv tcnlg d nfusn Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal 6 10 Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Attvtà dtra l

21 Asscat Dttrand spcalzzan ncarcat d d rcrca Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr 5 5 Ttal Stud d applcazn dll prprtà lttrnch d sld nanscpc Cmmssa: Prgtt: Dpartmnt: Rspnsabl: Svlupp d mtdlg cmputaznal pr la prgttazn carattrzzazn n slc d prcss d ntrss pr la sft mattr Mdllng prdttv dll funznaltà n sstm nanstrutturat d ntrss blgc tcnlgc Prgttazn Mlclar CAROTENUTO GIANFRANCO Rsultat cnsgut Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Prncpal cllabrazn Attvtà dtra l Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr Ttal

22 Attvtà RSTL Rcrca lbra Rspnsabl: AMBROSIO LUIGI Rsultat cnsgut Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Prncpal cllabrazn Attvtà dtra l Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr Prncpal rsrs strumntal utlzzat Ttal Rcrca lbra Rspnsabl: AMBROSIO LUIGI Rsultat cnsgut Prdtt dlla rcrca (2010)

23 ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Prncpal cllabrazn Attvtà dtra l Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr Prncpal rsrs strumntal utlzzat Ttal Stud dll'fftt mccanc chmc sull'ntrazn substrat plmrc cllul Rspnsabl: DE SANTIS ROBERTO Rsultat cnsgut Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Prncpal cllabrazn Attvtà dtra l Rsrs uman fnanzar

24 Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr Prncpal rsrs strumntal utlzzat Ttal Rscaldamnt dlttrc nl prcssng d plmr Rspnsabl: AMENDOLA Eugn Rsultat cnsgut Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Prncpal cllabrazn Attvtà dtra l Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal

25 Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr Prncpal rsrs strumntal utlzzat Ttal Stud dlla dnamca dlla transzn vtrsa d flm ultrasttl plmrc. Rspnsabl: GIORDANO MICHELE Rsultat cnsgut Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Prncpal cllabrazn Attvtà dtra l Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr Ttal

26 Prncpal rsrs strumntal utlzzat Crrlazn tra struttura prprtà d nancmpst plmrc funznal a bas d POSS Rspnsabl: PRACELLA MARIANO Rsultat cnsgut Prdtt dlla rcrca (2010) ann Brvtt Artc l Artc l nn Artcl n att d Cnvgn Lbr Rapprt Rsultat prgttua l Rsultat d valrzzaz n applcatva Abstrac t Prncpal cllabrazn Attvtà dtra l Rsrs uman fnanzar Ann rsrs fnanzar ttal allcat d cu rsrs da trz cst fguratv valr ffttv A B C D = A + C Valr n mglaa d ur Dat stratt dal PDGP prsnal quvalnt tmp pn rcrcatr ttal Rplg prsnal CNR Cnsuntv 2010 prsnal quvalnt tmp pn rcrcatr ttal Asscat Dttrand spcalzzan ncarcat d d rcrca Ultrr rsrs uman ch cllabran alla ralzzazn dll attvtà Brssta Assgnsta Prfssr vstatr Cllabratr prfssnal Altr Prncpal rsrs strumntal utlzzat Ttal Elnc pubblcazn dllʼisttut Brvtt

27 1 G.Barra, M.Lavrgna, G.Mnstr, F.Psctll - Fbr-rnfrcd plymrs, pxy-basd plymrc cmpstns and uss thrf 2 Dl Nbl M.A., Cnt A., Buncr G.G., Incrnat A.L., Massar A., Panza O. - Mthd fr prducng a flm f thrmplastc matral cntanng a substanc wth antmcrbal actvty and us f ths flm n th prductn f packagng fr fd Artcl 1 A Rcc*, M Grdan M Zarrll - A Lnar Numrcal Apprach t Smulat th Dlamnatn Grwth Intatn n Stffnd Cmpst Panls - JOURNAL OF COMPOSITE MATERIALS, Vl., Pagg. - 2 A. Glra, F. Causa, R. D Sants, K. E. Tannr, L. Ambrs - A Mult-cmpnnt Fbrrnfrcd PHEMA-basd Hydrgl/HAPEX Dvc fr Custmzd Intrvrtbral Dsc Prsthss - JOURNAL OF BIOMATERIALS APPLICATIONS, Vl., Pagg. - 3 Mrll A, Nclas L, Ambrs L, Santn M - A dgradabl syban-basd bmatral usd ffctvly as a bn fllr n vv n a rabbt - BIOMEDICAL MATERIALS, Vl. 5, Pagg. - 4 Mrn G, Valltta R, D Sants R, Ambrs L, Martna R - A nvl brackt bas dsgn: bmchancal stablty - EUROPEAN JOURNAL OF ORTHODONTICS, Vl. 32, Pagg F. Capzzut, F. Campa, G. Cartnut, M. M, Eva Mllla, F. Nclas - A smart multfunctnal plymr nancmpsts layr fr th stmatn f lw-vlcty mpact damag n cmpst structurs - COMPOSITE STRUCTURES, Vl. 92, Pagg Incrnat A.L., Buncr G.G., Cnt A., Lavrgna M., Dl Nbl M.A. - Actv systms basd n slvr-mntmrllnt nanpartcls mbddd nt b-basd plymr matrcs fr fd packagng applcatns - JOURNAL OF FOOD PROTECTION, Vl. 73, Pagg M.G. Raucc, V. DʼAntò, V. Guarn, S. Zpptll and L. Ambrs - Bcmpatblty and stcnductvty studs n hydrxyapatt-plymr cmpst scafflds prpard by chmcal synthss - JOURNAL OF APPLIED BIOMATERIALS & BIOMECHANICS, Vl. 92B, Pagg M.G.Raucc, V.DʼAntò, V.Guarn, E.Sardlla, P.Fava, L.Ambrs - Bmnralzd prus cmpst scafflds prpard by chmcal synthss fr bn tssu rgnratn - ACTA BIOMATERIALIA, Vl. 6(10), Pagg Gavars G, Fn M, Salvag J, Ncl Aldn N, Gardn R, Ambrs L, Nclas L, Santn M - Bn rgnratn ptntal f a syban-basd fllr: xprmntal study n a rabbt cancllus bn dfcts - JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, Vl. 21, Pagg Gulana Lan, Rbrt D Sants, Antn Glra, Trsa Russ, Davd Suárz Quntanlla, Albrt Lan, Rbrt Martna, Lug Nclas, Lug Ambrs - Calrmtrc and thrmmchancal prprts f ttanum-basd rthdntc wrs: DSC-DMA rlatnshp t prdct th lastc mdulus - JOURNAL OF BIOMATERIALS APPLICATIONS, Vl., Pagg Gaglard M., Slvstr D., Crstalln C., Guadagn M., Crfac G., Gust P - Cmbnd drug rlas frm bdgrabl blayrs catng fr ndvascular stnts - JOURNAL OF BIOMEDICAL MATERIALS RESEARCH-APPLIED BIOMATERIALS, Vl. 93B, Pagg Gaglard M., Slvstr D., Crstalln C., Guadagn M., Crfac G., Gust P. - Cmbnd drug rlas frm bdgrabl blayrs catng fr ndvascular stnts - JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, Vl. 93B, Pagg

28 13 Maran Praclla,M. Mnhaz-Ul Haqu, Vra Alvarz - Cmpatblzatn and Prprts f EVA Cplymrs Cntanng Surfac-Functnalzd Clluls Mcrfbrs - MACROMOLECULAR MATERIALS AND ENGINEERING, Vl. 295, Pagg D Guarnr, A D Capua, Vntr M, A Brzacchll, Pdn C, Marasc D, Ruv M, Ntt PA - Cvalnt mmblzd RGD gradnt n PEG hydrgl scaffld nfluncs cll mgratn paramtrs - ACTA BIOMATERIALIA, Vl. 6, Pagg R. Scaldafrr, C. Bnavlntà, G.P.Pp, G.Salzll, A.Brrll, I.Pdac - Currnt fluctuatns n plystyrn nan-cmpunds - EUROPEAN PHYSICAL JOURNAL B, Vl. 73, Pagg Salrn, A; Olvr, M; D Ma, E, Ntt PA, Rfan C, Clsm A, Guda V, Dallapccla B, Palma P, Prcaccn E, Brard AC, Vlard F, Tt A, Iannac S, - Dsgn f nvl thrphas PCL/TZ-HA bmatrals fr us n bn rgnratn applcatns - JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, Vl. 211, Pagg C Mla, G M Carlmagn, D annccharc, M Grdan, M Zarrll - Dtctn f dlamnatn n carbn-fbr-rnfrcd plymr wth lck-n thrmgraphy - PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART G- JOURNAL OF AEROSPACE ENGINEERING, Vl., Pagg Olvr, M; D Ma, E; Iannac, S - Effct f Mlcular Structur n Flm Blwng Ablty f Thrmplastc Zn - JOURNAL OF APPLIED POLYMER SCIENCE, Vl. 115, Pagg A. Brzacchll, Mayl L, Schavnat A, and Ambrs L - Effct f hyalurnc acd amd drvatv n qun synval flud vsclastcty - JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vl. 92, Pagg D'Antò V, D Capr MP, Amtran G, Smn M, Rng S, Spagnul G - Effct f mnral trxd aggrgat n msnchymal stm clls - JOURNAL OF ENDODONTICS, Vl. 36, Pagg D Sants, R.; Glra, A.; Prsc, D.; Amndla, E.; Puppuln, L.; Pzztt, G.; Rng, S.; Ambrs, L.; Nclas, L - Fast curng f rstratv matrals thrugh th sft lght nrgy rlas - DENTAL MATERIALS, Vl. 26, Pagg Barban N., Clucc M.L., Crstalln C., Gurra G.D., Rslln E - Gllan-adpc acd blnds crss-lnkd by mans f a dhydrthrmal tratmnt - JOURNAL OF APPLIED POLYMER SCIENCE, Vl. 118, Pagg Mara Graza Raucc, Vncnz Guarn, Lug Ambrs - Hybrd cmpst scafflds prpard by sl-gl mthd fr bn rgnratn - COMPOSITES SCIENCE AND TECHNOLOGY, Vl. 70, Pagg L.Vrdltt, E.D Ma, G.Frt, M.Lavrgna and S.Iannac - Hydratn-nducd rnfrcmnt f plyurthan cmnt fams: slvnt rsstanc and mchancal prprts - JOURNAL OF MATERIALS SCIENCE, Vl. 45, Pagg Guarn V., Guacc A., Ntt PA, Ambrs L. - Imag prcssng and fractal bx cuntng: usr assstd mthd fr mult-scal prus scafflds charactrzatn - JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, Vl. 21, Pagg Aurla M, Srrntn L, Iannac S - Imprvmnt f Mchancal Prprts f Structural Thrmplastc Cmpsts Usng a Ractv (Lw Mlcular Wght) Matrx Cmpnnt - POLYMER COMPOSITES, Vl., Pagg MA Alvarz-Prz, V.Guarn, V.Crll, L.Ambrs - Influnc f glatn cus n PCL lctrspun mmbrans n nrv utgrwth - BIOMACROMOLECULES, Vl. 11(9), Pagg D Ma, E; Mal, R; Iannac, S - Invstgatn f Thrmplastcty f Zn and Kafrn Prtns: Mxng Prcss and Mchancal Prprts, - JOURNAL OF POLYMERS AND THE ENVIRONMENT, Vl. 18, Pagg

29 29 Bnd, M; Brzacchll, A; Ntt, PA - Isthrmal and nn-sthrmal plymrzatn f mthyl mthacrylat n prsnc f multpl ntatrs - CHEMICAL ENGINEERING JOURNAL, Vl. 162, Pagg C.Manfrdn, V.Guarn, N.Zn, M.G.Raucc, A.Frrar, F.Grass, E.Gabus, S.Squarzn, A.Facchn, L.Ambrs, G.Lsgnl - Mnralzatn ccurs fastr n a nw bmmtc hyalurnc acd-basd scaffld - BIOMATERIALS, Vl. 31/14, Pagg V.Guarn, M.Lwandwska, M.Bl, B.Plak, L.Ambrs - Mrphlgy and dgradatn prprts f pcl/hyaff11-basd cmpst scafflds wth multscal dgradatn rat - COMPOSITES SCIENCE AND TECHNOLOGY, Vl. 70, Pagg L. Mnkva, Y. Pnva, M. Valchva, S. Flpp, M. Praclla, I. Angulls, P. Magagnn - Mrphlgy, Mcrhardnss and Flammablty f Cmpatblzd Plythyln/Clay Nancmpsts - POLYMER ENGINEERING AND SCIENCE, Vl., Pagg Ncca G, D'Antò V, Dsdr C, Rsstt DV, Valltta R, Baquala AM, Schwkl H, Lup A, Rng S, Spagnul G - N-actyl cystn drctd dtxfcatn f 2-hydrxythyl mthacrylat by adduct frmatn - BIOMATERIALS, Vl. 31(9), Pagg M. Aurla, L. Srrntn, L. Sangugn, S. Iannac - Nanflld Plythrsulfn as Matrx fr Cntnuus Glass Fbrs Cmpsts: Mchancal Prprts and Slvnt Rsstanc - ADVANCES IN POLYMER TECHNOLOGY, Vl., Pagg Salrn, A; Zpptll, S; D Ma, E, S. Iannac, PA Ntt, - Nvl 3D prus mult-phas cmpst scafflds basd n PCL, thrmplastc zn and ha prpard va suprcrtcal CO2 famng fr bn rgnratn - COMPOSITES SCIENCE AND TECHNOLOGY, Vl. 70, Pagg Trsa Russ, Antn Glra, Vncnz DʼAntò, Ug DʼAmra, Ganluca Amtran, Flava Blln, Rbrt D Sants, Gvann Ausan, Mchlna Cataur, Sandr Rng, Lug Ambrs - Ply(-caprlactn) rnfrcd wth sl-gl synthszd rganc-nrganc hybrd fllrs as cmpst substrats fr tssu ngnrng - JOURNAL OF APPLIED BIOMATERIALS & BIOMECHANICS, Vl. 8, Pagg L. Srrntn, E. D Ma, S. Iannac - Ply(thyln trphthalat) fams: Crrlatn btwn th plymr prprts and th famng prcss - JOURNAL OF APPLIED POLYMER SCIENCE, Vl. 116, Pagg A. Glra, R. D Sants, L. Ambrs - Plymr-basd cmpst scafflds fr tssu ngnrng - JOURNAL OF APPLIED BIOMATERIALS & BIOMECHANICS, Vl. 8, Pagg Y.H.Zhan, R.Patl, M.Lavrgna, F.Psctll, A.Khan, H.S.Xa, H.Bnkrra and P.Cats - Prcssng f plyurthan/carbn nantubs cmpsts usng nvl mnmxr - PLASTICS RUBBER AND COMPOSITES, Vl., Pagg Md. Mnhaz-Ul Haqu, Maran Praclla - Ractv Cmpatblzatn f Cmpsts f Ethyln-Vnyl Actat Cplymrs wth Clluls Fbrs - COMPOSITES PART A- APPLIED SCIENCE AND MANUFACTURING, Vl. 41, Pagg L J., Guarn V., Glra A., Ambrs L., Ta G., Km YH, Jung Y., Km SH, Km SH. - Rgnratn f Achllsʼ Tndn: Th Rl f Dynamc Stmulatn fr Enhancd Cll Prlfratn and Mchancal Prprts - JOURNAL OF BIOMATERIALS SCIENCE- POLYMER EDITION, Vl. 21, Pagg A. Martn, C. Frmcla, M. Grdan, M. Zarrll - Rnfrcmnt ffcncy f multwalld carbn nantub/pxy nan cmpsts - COMPOSITES SCIENCE AND TECHNOLOGY, Vl. 70, Pagg M. Dssì, M.G. Raucc, L. Ambrs - Rhlgcal and chmc-physcal studs n PCL/ HA synthszd by th sl-gl mthd - JOURNAL OF APPLIED BIOMATERIALS & BIOMECHANICS, Vl., Pagg A. Glra, A. Brzacchll, F. Causa, L. Ambrs - Rhlgcal charactrsatn f Hyalurnc acd drvatvs as njctabl matrals tward nuclus pulpsus rgnratn - JOURNAL OF BIOMATERIALS APPLICATIONS, Vl., Pagg. -